Gene Information

Name : tpx (Paes_0830)
Accession : YP_002015523.1
Strain : Prosthecochloris aestuarii DSM 271
Genome accession: NC_011059
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 912720 - 913220 bp
Length : 501 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCTGAGATTACATTGAAAGGAAATCCCGTCAATACTGTCGGGTCTCTTCCTCAAACAGGAGCTGCGGCTCCCGTTTT
TACGCTGGTGAAAGCTGATCTTTCTGAGGCTTCACTTGCTGACTTTGCAGGCAAGCGAGTTGTGCTGAATATTTTTCCGA
GTCTCGATACGCCTGTCTGTGCCGCATCGGTAAGGCGTTTTAACCTTGAAGTTGCCAATGTCCCCAATACTGTCGTTCTT
TGCATTTCTGCAGATCTTCCCTTTGCCCATAAACGGTTCTGCGAGGTTGAAGGGATTGACAATGTTGTCTCACTGTCAGT
TTTCCGTTCACCGGAATTCGGATTGGATTACGGCGTGACCATTGCTGATGGTCCGCTGAAAGGTATTCTGTCGCGGGCGG
TGATCATTGTTGACGAGAGCGGCAAAGTCACCTATAGCCAGCAGGTCCCCGAAATTACGATCGAACCGGATTACGAGGCA
GCGTTGCAGTCAATGGTGTAA

Protein sequence : 
MAEITLKGNPVNTVGSLPQTGAAAPVFTLVKADLSEASLADFAGKRVVLNIFPSLDTPVCAASVRRFNLEVANVPNTVVL
CISADLPFAHKRFCEVEGIDNVVSLSVFRSPEFGLDYGVTIADGPLKGILSRAVIIVDESGKVTYSQQVPEITIEPDYEA
ALQSMV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 6e-34 48
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 5e-34 48
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 6e-34 47
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 4e-34 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_002015523.1 thiol peroxidase VFG0087 Protein 2e-34 48