Gene Information

Name : guaA (Paes_0315)
Accession : YP_002015019.1
Strain : Prosthecochloris aestuarii DSM 271
Genome accession: NC_011059
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 339406 - 340962 bp
Length : 1557 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTTCACGTTTATGCAGTCTGTTCTTGTACTCGATTTCGGCTCTCAATATACCCAGCTCATTGCCAGGAGAATCCGCGA
AATCGGGATCTATTCTGAAATTATCCCATACAGCACACCGCTGGACACCATCAAAGAGCACAAGCCAGGAGCAATCATTC
TTTCCGGAGGGCCAAACAGCGTCTACGGCGAAGATGCGCTGCTCCCCGATAAAGGAATATTCTCTCTCGGAGTGCCGATT
CTGGGGATCTGTTATGGTCTGCAGGTTATCGCGACGCACTTTGGAGGAGAGGTCGCCGTATCGTCAAAACAGGAATTCGG
TCGCGCCAAAATACTGGTTGACCGGGAAAACGACGTAGCCGCAAGCAGGCTTTTCAGCGATATTCCCGATTCGGATGTCT
GGATGAGCCATGGCGACAAGGTCGTCAGAATGCCTGAAGGATTTTCCATTACCGCAAGCAGCGGCAACTCTGAAATGTGC
GCTATTGAAGCAACGGGCAGCAAAGCCGCTCTGAAGGTCTATGGACTGCAGTTCCATCCCGAAGTCCAGCACTCACTCTA
CGGAAAACAGCTGCTCTCAAACTTTCTTATCGATATCGCCGGGCTCAAGCCCGACTGGTCACCTAAAAGCTTTATCGAGC
ATCAGATCGAAGAGATTCGAAAAACAGCAGGCAACGCTACCGTCATTTGCGGTATCAGCGGCGGCGTCGATTCCACGGTA
GCCGCAGTGCTCGTCAGCAAAGCCATCGGGAAAAAACTCCACTGCGTCTTTGTCAACAACGGTCTGTTGCGTAAAAACGA
GGGTGAAAAAGTGATGAGTATCCTCAAGCCGCTCGGCCTCAACATCACGATGGTCGATGCCGAAGAGATCTTCCTCAAAC
GCCTCAAAAGCGTTGCCTCACCCGAGAAAAAGCGCAAAATCATCGGCCGGACCTTTATCCATATTTTTGAGGAACAGATT
CACGAAGAAAAATTTCTCGTTCAGGGGACCCTCTATCCTGACGTCATCGAAAGCGTCAGCGTCAAAGGACCGTCAGAAAC
CATCAAGTCGCACCACAATGTCGGCGGCCTGCCGAAACGCATGAAACTCAAACTGATCGAACCCCTGCGGGAGCTTTTCA
AAGATGAAGTCCGCGCCGTCGGGCGAGAACTCGGTATCGACGAGGATATCCTCATGCGCCACCCCTTCCCGGGCCCTGGT
CTGGCTGTACGCGTCCTTGGATCACTCACCAAAGAACGGCTCGATATCCTGCGGGATGCAGATGAAATCTTCCTCGAAGA
GCTCAAAAAGCAGAACCTCTATCAGCAGGTCTGGCAGGCGTTCTCCGTCCTGCTGCCGGTCCAGTCCGTCGGCGTCATGG
GTGATAAACGAACCTACGAAAACGTCCTTGCGCTGCGGGCTGTTGAATCTTCCGACGGCATGACAGCTGACTGGGCGCAT
CTGCCGCACGAATTCCTCTCTCATGTTTCAAACCGCATCATCAACGAAGTTCGCGGTATCAACAGGGTTGCCTACGACAT
CTCCTCCAAACCACCGGCAACCATCGAGTGGGAATGA

Protein sequence :
MFTFMQSVLVLDFGSQYTQLIARRIREIGIYSEIIPYSTPLDTIKEHKPGAIILSGGPNSVYGEDALLPDKGIFSLGVPI
LGICYGLQVIATHFGGEVAVSSKQEFGRAKILVDRENDVAASRLFSDIPDSDVWMSHGDKVVRMPEGFSITASSGNSEMC
AIEATGSKAALKVYGLQFHPEVQHSLYGKQLLSNFLIDIAGLKPDWSPKSFIEHQIEEIRKTAGNATVICGISGGVDSTV
AAVLVSKAIGKKLHCVFVNNGLLRKNEGEKVMSILKPLGLNITMVDAEEIFLKRLKSVASPEKKRKIIGRTFIHIFEEQI
HEEKFLVQGTLYPDVIESVSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIDEDILMRHPFPGPG
LAVRVLGSLTKERLDILRDADEIFLEELKKQNLYQQVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESSDGMTADWAH
LPHEFLSHVSNRIINEVRGINRVAYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-126 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-126 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-126 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-119 49