Gene Information

Name : Paes_1866 (Paes_1866)
Accession : YP_002016525.1
Strain : Prosthecochloris aestuarii DSM 271
Genome accession: NC_011059
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 2040143 - 2040892 bp
Length : 750 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGCCTCCAATCAATATCGTCATTCTGATTCCCGCAAGGCTCAATTCCAGCAGACTGCCCAATAAAATGCTTGCCGATAT
CGAGGGAGCTCCGCTGATTGTCAGAACGTGGCAGCAGGCGCAGCAGTCAAGCCTGACCCGGCAGGTGGTTATCGCTACAG
ACAGTGAGGAGATTGCCGGTGTGATGAAGGCGTGTGGCGCCGATGTCGTTATGACCTCCCCTGACGCGCGTTGCGGTACC
GAGCGGATTGCTGAAGCGGCCGAAAATATTGATGCAGACGTGTTTGTCAATCTGCAGGGCGACGAACCGCTGATCGATCC
GGGGAATATCGACCTGGTTATCAAACCGTTTCTCCAGGAGAACCCTCCGGACTGCTCGACGTTGGTCTATCGGCTTCTTG
CGGAGGATTATGCCGCATTGCATGATCCCAACATCGTCAAAGTGGTCATGGACAGTCAGTCCAATGCGCTTTATTTTTCC
AGGAGCCCTCTGCCGTATCAGCGAGAAACCTATGCGGCAACCCGTTGCTTTCGTCATATCGGTATTTATGCCTTTCGCGC
AGGTGTGCTGAGGATGTTTTCAGAACACGGGCCTTCAATGCTTGAGGAAGCGGAGTCTCTCGAACAGCTTCGTCTTGTCG
AAAATGGTTATAGCATTCGCTGTGTAGAGACCGATGTCGATATGCCGGGCGTCAATACTCATGAGGATCTTGAACTTGTT
CGTCGCCTTTATCGCTCCCGTCGGTCATGA

Protein sequence :
MPPINIVILIPARLNSSRLPNKMLADIEGAPLIVRTWQQAQQSSLTRQVVIATDSEEIAGVMKACGADVVMTSPDARCGT
ERIAEAAENIDADVFVNLQGDEPLIDPGNIDLVIKPFLQENPPDCSTLVYRLLAEDYAALHDPNIVKVVMDSQSNALYFS
RSPLPYQRETYAATRCFRHIGIYAFRAGVLRMFSEHGPSMLEEAESLEQLRLVENGYSIRCVETDVDMPGVNTHEDLELV
RRLYRSRRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-39 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-38 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-39 42