Gene Information

Name : lysS (Paes_1508)
Accession : YP_002016175.1
Strain : Prosthecochloris aestuarii DSM 271
Genome accession: NC_011059
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 1649131 - 1650675 bp
Length : 1545 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACAGACGCACAGGACACGAATCTCCATGACAGCCCGTATAGCCAGGAGAGCGAACACAAAGCCCTCAATGATCAGAT
GCACAGACGCCTTGAAGAACGAAAGCTGCTTGAAGAAGAAGGCGTCAGACCATACCCCTACGGGTTCGACGTAACGAGGC
ATTCCAGAGATATCAAAGAGAACTTCCTTGAAGAAACACCTGAAACGGTATCAGTTGCCGGTCGTATCATGGCCGTCAGA
AAAATGGGAAAAGCCTCGTTTTTCAACATTCAGGATGCAAAGGGACGCATACAGGTCTACATGAAACGCGACGATGTCGG
GCAGGATGCATACAGGATATTCAAACTGCTTGATATCGGTGATATTGTCGGCGTCAAAGGGTTCACGTTCAGAACCAAAA
CCGGTGAAATCTCGATCCACGCCGAAGAGTTCATGCTTCTGAGTAAATCGCTCAGGCCTATACCTGTCGCCAAAGAAAAA
GAAGTTGACGGCCAGAAAGTCACCTATGACGCATTCAGCGACAAGGAACTGCGCTACCGTCAGCGTTACGTCGACCTGAT
TGTCAATCCTGAAGTAAGAAATACGTTTGTCAAGCGCTCCGCGATCGTCACCTTCATGCGTACCTTCTTTTCTGAAAAAG
GATACCTTGAAGTCGAAACGCCTATTCTCCAGCCGGTCTACGGTGGTGCAGCAGCACGGCCGTTCACAACACACCATAAC
GCGCTGGACATGGAGCTCTACCTCAGGATCGCCAATGAGCTGTATCTCAAGCGGCTTATCGTAGGCGGTTTTGACGGTGT
CTTTGAATTTGCCAAAGACTTCCGCAACGAAGGCATTGACCGCTTTCACAATCCTGAATTCACTCAGGTAGAACTCTATG
TCGCCTACAAGGATTACTACTGGATGATGGAACTGGTCGAACAGCTCATCTACCGGGCCAACCTTGCTGTCAACAACAGC
GAGAACACAACGTTTCTCGACAATGAGATCTCGCTCAAGCCTCCATTCACGAGGCTCTCGATCGCTGATGCCATCATGCA
GTACTGTGACCGCGATATCAGCGGGAAGTCTGAATCCGAACTGAGAAACATCGCCAAGGATCTCGGACTGGAACTCGACC
CGAAAATCAGCAGCGGAAAAATCATTGATGAAATCTTCGGTGAGTTCGTTGAGCCAAAGCTCATCCAGCCGACATTCATT
ATGGATTATCCGACAGAAATGTCACCGCTGGCAAAAGAACACCGTTCAAAAGAGGGTGTCGTCGAGCGATTTGAGCTGAT
CGTCGGAGGCAAAGAGCTCTGTAATTCCTTCTCCGAACTCAATGATCCGGTCATTCAGCGCAACAGACTCGAAGAACAGG
CAAAACTCCGTCTTCGCGGGGACGATGAAGCCATGGTGGTCGATGAAGATTTTCTTCGCGCCCTCGAGTACGGCATGCCG
CCGTGCGCTGGCCTCGGCATCGGCATCGATCGACTGGTCATGCTTCTGTGCGGCGAAGAATCGATCAGGGATGTCATTTT
CTTTCCTCATCTGAAACCGGAATAA

Protein sequence :
MTDAQDTNLHDSPYSQESEHKALNDQMHRRLEERKLLEEEGVRPYPYGFDVTRHSRDIKENFLEETPETVSVAGRIMAVR
KMGKASFFNIQDAKGRIQVYMKRDDVGQDAYRIFKLLDIGDIVGVKGFTFRTKTGEISIHAEEFMLLSKSLRPIPVAKEK
EVDGQKVTYDAFSDKELRYRQRYVDLIVNPEVRNTFVKRSAIVTFMRTFFSEKGYLEVETPILQPVYGGAAARPFTTHHN
ALDMELYLRIANELYLKRLIVGGFDGVFEFAKDFRNEGIDRFHNPEFTQVELYVAYKDYYWMMELVEQLIYRANLAVNNS
ENTTFLDNEISLKPPFTRLSIADAIMQYCDRDISGKSESELRNIAKDLGLELDPKISSGKIIDEIFGEFVEPKLIQPTFI
MDYPTEMSPLAKEHRSKEGVVERFELIVGGKELCNSFSELNDPVIQRNRLEEQAKLRLRGDDEAMVVDEDFLRALEYGMP
PCAGLGIGIDRLVMLLCGEESIRDVIFFPHLKPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-94 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002016175.1 lysyl-tRNA synthetase VFG1668 Protein 2e-94 46