Gene Information

Name : thyA (ATP_00320)
Accession : YP_002004353.1
Strain : Candidatus Phytoplasma mali AT
Genome accession: NC_011047
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 402931 - 403797 bp
Length : 867 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCAAGCTTATTTAAATTTATGTCGAGATATTTTAAATTATGGGAAAAAAAAAATAGATCGTACAAAAACAGGAACTAG
AAGTATTTTTGGTTATCAAATGCGTTTTAATTTAGAAAAAGGATTTCCTTTATTGACTACTAAAAAAATGAATTTTAAAG
CTATTATACATGAATTATTATGGTTTATTAAAGGTGATACTAATATTCGTTATTTGGTACAAAATAATGTTAATATCTGG
AATGAATGGCCTTATCAAAAATATTGTAATTCTAACTTTTTTCAAAATTTAACATTACAAGAATTTATTGATAAGATTAT
AATAGATGAAAAGTTTGCTAAAATTCACGGAGATTTAGGTCCTATTTATGGTCATCAATGGAGAAATTTTCAAGGCATTG
ATCAATTAACTGATTTAATTTCAGAAATTAAAAAAAATCCTCATTCAAGACGTTTAATTTTAACTGCTTGGGATCCTACT
GTAATTAAAGATATGTTATTACCACCTTGTCATGTTATGATACAGTGTTATGTTGAAAAAAATAAAATCTCTATGCAACT
TTATCAAAGAAGTGGAGATGTTTTTTTAGGTATACCATTTAATATTGCTTCTTATTCTTTGTTATTAATTATAATTGCTC
AATGTACAGGTTTAAAACCTTTTGAATTTATTCATACTATAGGTGACGCTCATATTTATAATAACCATATAGAACAAATT
CAAAAACAAATAAAAAGAATTCCTAAAAAGTTACCAATTATGACTTTAAATCCTCACATAATCGACATTAACCAATTTAC
ATTTAATGACTTTAATTTAGAAAAATATGAATCTTATGGTATTTTGAAAGGGGTTGTTGCTGTATGA

Protein sequence :
MQAYLNLCRDILNYGKKKIDRTKTGTRSIFGYQMRFNLEKGFPLLTTKKMNFKAIIHELLWFIKGDTNIRYLVQNNVNIW
NEWPYQKYCNSNFFQNLTLQEFIDKIIIDEKFAKIHGDLGPIYGHQWRNFQGIDQLTDLISEIKKNPHSRRLILTAWDPT
VIKDMLLPPCHVMIQCYVEKNKISMQLYQRSGDVFLGIPFNIASYSLLLIIIAQCTGLKPFEFIHTIGDAHIYNNHIEQI
QKQIKRIPKKLPIMTLNPHIIDINQFTFNDFNLEKYESYGILKGVVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 9e-61 47
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 5e-46 45