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Name : leuS (NGK_0009) Accession : YP_002000634.1 Strain : Neisseria gonorrhoeae NCCP11945 Genome accession: NC_011035 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 6504 - 9134 bp Length : 2631 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAACATTACCAGCCCGCCGCCATCGAGCCTGCGGCGCAGAAAAAATGGGACGACGCCCGTATTTCCAACGTCTC CGAAGACGCTTCCAAACCCAAATATTATTGCCTTTCGATGTTCCCTTACCCTAGCGGCAAGCTGCATATGGGGCATGTAC GCAACTACACCATCGGCGACGTATTGAGCCGCTTCAAACTTTTAAACGGCTTCAACGTTATGCAGCCTATGGGTTGGGAC GCGTTCGGCATGCCGGCGGAAAATGCGGCGATGAAAAACAACGTCGCCCCCGCCGCTTGGACCTACGACAACATCGAATA CATGAAAACCCAGCTCAAAAGCCTGGGTTTTGCGGTTGACTGGGAACGCGAAGTCGCCACCTGCAAACCCGAATACTACC GCTGGGAACAATGGCTGTTTACCAAGCTGTTTGAAAAAGGCATCGTCTATCGCAAAAACGGCACGGTGAACTGGGACCCG GTCGACCAAACCGTCCTTGCCAACGAGCAAGTCATCGACGGACGCGGCTGGCGTTCGGGCGCGTTGATCGAAAAACGCGA AATCCCGATGTATTACTTCAAAATCACGGATTACGCCGAAGAGCTGCTCAACGATTTGGACAAGCTGGAACACTGGCCGG AACAAGTCAAAACCATGCAGCGCAACTGGATCGGCAAATCTCGCGGCATGACCGTGCGCTTCGCCGTTTCAGACGACAGC AAGCAAGGTTTGGAAGGCGATTACGCGAAATTCCTGCAAGTTTATACCACCCGCCCCGACACGCTGATGGGTGCGACTTA TGTCGCTGTTGCCGCCGAACATCCGCTGGCAACAGCCGCAGCCGCCGACAAACCCGAATTGCAGGCATTTATCGCCGAAT GCAAAGCCGGTTCGGTTGCCGAAGCCGATATGGCGACGATGGAGAAAAAAGGCGTGCCGACCGGCCGCTACGTCGTCAAC CCGCTCAACGGCGACAAGCTGGAAGTGTGGATTGCCAACTATGTCTTGTGGGGCTACGGCGACGGCGCGGTGATGGCTGT TCCGGCGCACGACGAACGCGATTTCGAGTTTGCCGCCAAATACAATCTGCCGAAAAAACAAGTCATTGCCGTCGGCGACA ACGCATTCGACGCAAACCGATGGCAAGAATGGTACGGCGACAAAGAAAACGGCGTATTGGTCAACAGCGGCGACTTGGAC GGCTTGGATTTTCAGACGGCATTTGATGCCGTTGCCGCCAAGCTGCAAAGCCAAGGTGCGGGCGAACCGAAAACCCAATA CCGCCTGCGCGACTGGGGCATTTCGCGCCAACGCTACTGGGGCTGCCCGATTCCCATCGTCCATTGCGAAAAATGCGGAG ACGTTCCCGTCCCTGCCGACCAACTGCCCGTCGTCCTGCCTGAAAACGTCGTACCCGACGGTATGGGTTCGCCGCTGGCA AAAATGCCCGAGTTTTACGAAACTTCCTGCCCGTGCTGCGGCGGCGCGGCGAAACGCGAAACCGACACCATGGACACCTT CATGGAGTCGAGCTGGTACTTCTTCCGCTATATGTCGCCCAAGTTTTCAGACGGCATGGTATCGGCAGAATCCGCGAAAT ACTGGGGCGCGGTCGACCAATACATCGGCGGCATCGAACACGCGATTTTGCACCTCCTGTACGCGCGCTTCTTCACCAAA CTGATGCGCGACGAAGGTTTGGTCAATGTTGACGAACCGTTTGAACGCCTGCTCACGCAAGGTATGGTCGTCTGCGAAAC CTACTACCGCGAAAACGACAAAGGCGGCAAAGACTGGATCAACCCCGCCGATGTCGAGCTGACTTTCGATGACAAAGGCC GCCCCGTTTCCGCCGTCCTCAAAGCCGACGGACTGCCCGTCGTCATCAGCGGCACGGAAAAAATGTCCAAATCCAAAAAC AACGGCGTCGATCCGCAAGAACTGATTAACGCCTACGGCGCGGACACCGCCCGCCTGTTCATGATGTTCGCCGCACCGCC CGAACAGTCCCTCGAATGGAGCGACAGCGGCGTCGAAGGTGCACACCGCTTCCTGCGCCGTCTGTGGCGTACCGTTTACG AATACCTGAAGCAAGGCGGCGCGGTCAAAGCATTTGCAGGCAACCAAGACGGTTTGTCTAAAGAACTCAAAGACCTGCGC CACAAACTGCATTCCACCACCGCCAAAGTCAGCGACGACTACGGCCGCCGCCAGCAGTTCAACACCGCCATCGCCGCCGT GATGGAACTGCTCAACCAATACGACAAAACCGACACCGGCAGCGAACAAGGCCGCGCCGTCGCCCAAGAAGTATTGGAAG CCGCCGTACGCCTGTTGTGGCCCATCGTGCCGCACATCTGCGAAACCCTGTGGAGCGAATTGAACGGCGCGAAACTGTGG GAAGCAGGCTGGCCGACAGTCGACGAAGCCGCCCTGGTCAAATCCGAAATCGAAGTGATGGTTCAAGTCAACGGCAAACT GCGCGGCAAAATCACCGTCGCCGCCGACGCCTCCAAAGCCGACCTCGAAGCCGCCGCACTCGCCAACGAAGGCGCAGTGA AATTCATGGAAGGCAAGCCTGCGAAGAAAATCATCGTCGTACCGGGCAGACTGGTGAACATCGTCGTCTAA Protein sequence : MQEHYQPAAIEPAAQKKWDDARISNVSEDASKPKYYCLSMFPYPSGKLHMGHVRNYTIGDVLSRFKLLNGFNVMQPMGWD AFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAVDWEREVATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDP VDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDS KQGLEGDYAKFLQVYTTRPDTLMGATYVAVAAEHPLATAAAADKPELQAFIAECKAGSVAEADMATMEKKGVPTGRYVVN PLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFAAKYNLPKKQVIAVGDNAFDANRWQEWYGDKENGVLVNSGDLD GLDFQTAFDAVAAKLQSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEKCGDVPVPADQLPVVLPENVVPDGMGSPLA KMPEFYETSCPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVSAESAKYWGAVDQYIGGIEHAILHLLYARFFTK LMRDEGLVNVDEPFERLLTQGMVVCETYYRENDKGGKDWINPADVELTFDDKGRPVSAVLKADGLPVVISGTEKMSKSKN NGVDPQELINAYGADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGGAVKAFAGNQDGLSKELKDLR HKLHSTTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGSEQGRAVAQEVLEAAVRLLWPIVPHICETLWSELNGAKLW EAGWPTVDEAALVKSEIEVMVQVNGKLRGKITVAADASKADLEAAALANEGAVKFMEGKPAKKIIVVPGRLVNIVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-137 | 41 |
