Gene Information

Name : NGK_0622 (NGK_0622)
Accession : YP_002001247.1
Strain : Neisseria gonorrhoeae NCCP11945
Genome accession: NC_011035
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 517391 - 518794 bp
Length : 1404 bp
Strand : +
Note : unwinds double stranded DNA

DNA sequence :
ATGAACGATTACGCAGCTATGCCGCCTGAAGGCCGTGAGGTCGGCGCATTGTCGCTGCCTCCGCATTCGATGGAGGCGGA
ACAATCCGTTTTGGGCGGTTTGATGCTGGAAAATCCGGCTTGGGACAGGATTGCCGATGTGGTTTCGGGAGAGGATTTCT
ACCGCCACGAACACCGCCTGATTTTCCGATCCATTGCCAAATTAATCAATGAGGGCCGTCCCGCAGATGTGATTACGGTT
CAGGAAGATTTGCAGCGGAACGAAGAATTGGAAGCGGCAGGCGGATTTGAATATCTGATTACACTGGCGCAAAACACCCC
GTCTGCCGCCAACATCCGCCGCTACGCCGAAATCGTACGCGAGCGTTCCATTATGCGCCAACTCGCCGAAGTGGGGACGG
AAATCGCCCGCAGCGCATACAATCCGCAAGGCAGGGACGCGGGGCGGCTTTTGGATGAGGCGGAAAACAAAGTGTTTCAA
ATCGCCGAAAGCACCGCCAAATCCAAGCAGGGCTTTTTGGAGATGCCCGATTTGCTGAAAGAAGTCGTACAGCGCATCGA
TATGCTTTATTCGCGCGACAATCCCGATGAAGTTACCGGCGTGCCGACAGGGTTTGCCGACCTCGATAAAAAAACATCCG
GCCTCCAGCCCGGCGACCTGATTATCGTCGCCGGCCGCCCGTCTATGGGTAAAACCGCGTTCTCCATCAATATTGCCGAG
TATGTCGCCATTGAAAAACATTTGCCCGTCGCCGTTTTCTCGATGGAAATGGGCGGTGCGCAGTTGGTCATGCGTATGCT
CGGCTCGGTCGGACGGCTGGATCAAAGCGTTTTGAAAACCGGCAGGCTCGAAGACGAACACTGGGGCCGTCTGAACGAGG
CAGTCGTCAAACTCTCAGACGCGCCCGTGTACATCGACGAGACCCCGGGCCTGACTGCGCTCGAACTGCGCGCCCGCGCC
CGTCGTCTCGCCCGTCAATTTAACAATAAGCTGGGATTAATCGTCATTGACTACCTGCAACTGATGGCGGGATCCGGCCG
TTCGGACAACCGCGCTTCCGAGCTTGGGGAAATTTCCCGTTCCCTCAAAGCTTTGGCAAAAGAGTTGCAAGTCCCCATCA
TCGCCCTGTCGCAATTGAGCCGCACTGTCGAACAGCGCACCGACAAACGCCCGATGATGTCCGACCTCCGCGAATCCGGT
GCTATCGAGCAGGATGCCGACCTGATTATGTTTATGTACCGCGACGAATACTACAACCAGGACTCACCCATGAAAGGCCT
TGCCGAATGTATCATCGGCAAACACCGCAACGGCCCGGTCGGAAAAGTCATCCTGACGTGGATGGGGCAGTTTACCAAAT
TCGGAAATGCCGCCTATATCCCGGAATCGGCAGCGGAAGACTGA

Protein sequence :
MNDYAAMPPEGREVGALSLPPHSMEAEQSVLGGLMLENPAWDRIADVVSGEDFYRHEHRLIFRSIAKLINEGRPADVITV
QEDLQRNEELEAAGGFEYLITLAQNTPSAANIRRYAEIVRERSIMRQLAEVGTEIARSAYNPQGRDAGRLLDEAENKVFQ
IAESTAKSKQGFLEMPDLLKEVVQRIDMLYSRDNPDEVTGVPTGFADLDKKTSGLQPGDLIIVAGRPSMGKTAFSINIAE
YVAIEKHLPVAVFSMEMGGAQLVMRMLGSVGRLDQSVLKTGRLEDEHWGRLNEAVVKLSDAPVYIDETPGLTALELRARA
RRLARQFNNKLGLIVIDYLQLMAGSGRSDNRASELGEISRSLKALAKELQVPIIALSQLSRTVEQRTDKRPMMSDLRESG
AIEQDADLIMFMYRDEYYNQDSPMKGLAECIIGKHRNGPVGKVILTWMGQFTKFGNAAYIPESAAED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 2e-90 49
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 6e-82 47
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 1e-80 46
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 5e-81 46
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 2e-81 46
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 1e-79 45
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 8e-80 45
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 8e-80 45
dnaB1 YP_005176258.1 replicative DNA helicase Not tested ICEPmu1 Protein 7e-70 42