Gene Information

Name : guaA (NGK_2643)
Accession : YP_002003268.1
Strain : Neisseria gonorrhoeae NCCP11945
Genome accession: NC_011035
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2217911 - 2219476 bp
Length : 1566 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCAAGACAAAATCCTCATCCTCGACTTCGGTTCGCAAGTTACCCGGCTGATCGCCCGCCGCGTGCGCGAAGCACA
CGTTTACTGCGAGCTGCATTCCTTCGATATGCCTTTGGACGAAATCAAAGCCTTCAACCCCAAAGGCATCATCCTTTCCG
GCGGCCCTAATTCTGTTTACGAATCCGACTATCAAGCCGATACCGGTATTTTTGATTTGGGCATTCCGGTTTTGGGCATC
TGCTACGGCATGCAGTTTATGGCGCACCACTTGGGTGGCGAAGTGCAGCCCGGCAACCAGCGCGAATTCGGTTACGCGCA
AGTCAAAACCATCGACAGCGGACTGACACGCGGCATTCAAGACGACGCGCCCAACACACTCGACGTATGGATGAGCCACG
GCGACAAAGTGTCCAAACTGCCCGACGGTTTCGCCGTCATCGGCGACACTCCGTCCTGCCCGATTGCCATGATGGAAAAC
ACCGAAAAACAATTCTATGGCATCCAGTTCCACCCCGAAGTTACCCACACCAAACAAGGCCGCGCCCTGTTGAACCGCTT
TGTCTTGGATATTTGCGGCGCGCAACCGGGCTGGACGATGCCCAACTACATCGAAGAAGCCGTTGCCAAAATCCGCGAAC
AAGTCGGCAGCGACGAAGTGATTTTAGGTCTGTCCGGCGGCGTGGACTCTTCCGTAGCCGCCGCGCTGATTCACCGCGCC
ATCGGCGACCAACTGACCTGCGTGTTCGTCGATCACGGTTTGTTGCGCCTGAACGAAGGCAAAATGGTGATGGATATGTT
CGCCCGCAACTTGGGTGTGAAAGTGATACACGTCGATGCCGAAGGGCAGTTTATGGCGAAACTCGCCGGCGTGACCGACC
CTGAGAAAAAACGCAAAATCATCGGCGCGGAATTTATCGAAGTATTTGATGCCGAAGAGAAAAAACTCACCAACGCCAAA
TGGCTGGCGCAAGGCACGATTTACCCTGACGTAATCGAATCCGCCGGTGCGAAAACCAAAAAAGCCCACGCCATCAAATC
CCACCACAACGTCGGCGGCCTGCCTGAAAATATGAAGCTCAAACTGCTTGAGCCCTTGCGCGACTTGTTCAAAGACGAAG
TGCGCGAGTTGGGCGTGGCTTTGGGCCTGCCGCGCGAAATGGTGTACCGCCACCCCTTCCCGGGCCCCGGTTTGGGTGTG
CGCATCTTGGGCGAAGTGAAAAAAGAATACGCCGACTTGCTGCGTCAGGCGGACGATATTTTCATCCAAGAATTACGCAA
TACTACCGACGAAAACGGCACGTCTTGGTATGACCTGACCAGCCAGGCATTTGCCGTATTCCTGCCCGTCAAATCCGTCG
GCGTGATGGGCGACGGCCGCACTTACGACTACGTCGTCGCACTGCGCGCAGTCATCACCAGCGACTTTATGACTGCACAC
TGGGCAGAGCTGCCATACTCACTGCTCGGCCGCGTGTCCAACCGCATCATCAACGAAGTCAAAGGCATCAACCGCGTGGT
GTACGATGTCAGCGGCAAACCGCCCGCCACCATCGAGTGGGAATAA

Protein sequence :
MTQDKILILDFGSQVTRLIARRVREAHVYCELHSFDMPLDEIKAFNPKGIILSGGPNSVYESDYQADTGIFDLGIPVLGI
CYGMQFMAHHLGGEVQPGNQREFGYAQVKTIDSGLTRGIQDDAPNTLDVWMSHGDKVSKLPDGFAVIGDTPSCPIAMMEN
TEKQFYGIQFHPEVTHTKQGRALLNRFVLDICGAQPGWTMPNYIEEAVAKIREQVGSDEVILGLSGGVDSSVAAALIHRA
IGDQLTCVFVDHGLLRLNEGKMVMDMFARNLGVKVIHVDAEGQFMAKLAGVTDPEKKRKIIGAEFIEVFDAEEKKLTNAK
WLAQGTIYPDVIESAGAKTKKAHAIKSHHNVGGLPENMKLKLLEPLRDLFKDEVRELGVALGLPREMVYRHPFPGPGLGV
RILGEVKKEYADLLRQADDIFIQELRNTTDENGTSWYDLTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVITSDFMTAH
WAELPYSLLGRVSNRIINEVKGINRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-136 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-136 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-136 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-119 50