Gene Information

Name : NGK_2322 (NGK_2322)
Accession : YP_002002947.1
Strain : Neisseria gonorrhoeae NCCP11945
Genome accession: NC_011035
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 1924790 - 1927384 bp
Length : 2595 bp
Strand : +
Note : This protein performs the mismatch recognition step during the DNA repair process

DNA sequence :
ATGTCCAAATCCGCCGTTTCCCCAATGATGCAGCAATACCTCGGCATAAAAGCGCAACATACCGACAAACTAGTGTTTTA
CCGTATGGGTGATTTTTACGAGCTGTTTTTGGATGACGCGGTGGAAGCGGCGAAATTGTTGGACATCACCCTGACCACAC
GCGGGCAGATGGACGGCGTGCCGATTAAAATGGCGGGCGTTCCGTTTCACGCGGCGGAACAGTATCTGGCGCGCCTGGTC
AAGTTGGGCAAAAGCGTGGCGATTTGCGAACAGGTCGGCGAAGTCGGCGCGGGCAAAGGGCCGGTGGAGCGCAAAGTCGT
GCGCATCGTAACGCCCGGCACGCTAACCGATTCCGCATTACTGGAAGACAAGGAAACCAACCGCATCGTTGCCGTGTCTC
CCGACAAAAAATACATCGGTTTGGCGTGGGCATCGCTGCAAAGCGGCGAATTCAAAACCAAGCTGACAACTGCGGATAAA
TTGAACGACGAACTGGCGCGCCTGCAGGCGGCGGAAATTTTGCTGCCGGACAGTAAAAACGCACCGCAACTTCAGACGGC
ATCGGGTGTTACACGCCTGAACGCGTGGCAGTTTGCCGCCGACGCGGGGGAAAAACTGCTGACGGAATATTTCGGCTGCC
AAGATTTGCGCGGCTTCGGTTTGGACAGCAAAGAACACGCCGTTTCGATTGGCGCGGCAGGTGCGCTGTTGAACTATATC
CGCCTGACGCAAAACCTGATGCCGCAACATTTGGACGGCCTGTCGCTCGAAACCGACAGCCAATATATCGGCATGGATGC
CGCCACGCGCCGCAATCTCGAAATCACGCAAACCCTCTCCGGCAAAAAAACGCCGACCCTGTTTTCCATACTCGACGGCT
GCGCCACCCACATGGGCAGCCGCCTGTTGGCATTGTGGCTGCACCACCCTTTACGCAACCGCGCCCACATCCGAGCGCGC
CAAGAAGCCGTAACCGCGCTGGAAAGCCAATACGAACCCCTCCAATGCCATCTGAAGAGCATTGCCGACATCGAACGTAT
CGCCGCCCGCATCGCCGTCGGCAATGCCCGCCCGCGCGATTTGGCATCTTTACGCGACAGTCTGTTCGAGTTGGCACAAA
TCGACTTGTCCGCAACCGGCAGCAGCCTGTTGGAAACCCTTAAAGCCGTTTTCCCCGAAACCCTGCCAGTTGCCGAAACC
CTCAAAGCCGCCGTGATGCCCGAACCTTCCGTCTGGCTGAAAGACGGCAATGTCATCAACCACGGTTTTCATCCCGAACT
GGACGAATTGCGCCGCATTCAAAACCATGGCGACGAATTTTTGCTGGATTTGGAAGCCAAGGAACGCGAACGTACCGGTT
TGTCCACACTCAAAGTCGAGTTCAACCGCGTTCACGGCTTTTACATTGAATTGTCCAAAACCCAAGCCGAACAAGCACCT
GCCGACTACCAACGCCGGCAAACCCTCAAAAACGCCGAACGCTTCATCACGCCGGAACTGAAAGCCTTTGAAGACAAAGT
GCTGACTGCTCAAGACCAAGCCCTCGCCTTAGAAAAACAACTCTTTGACGGCGTATTGAAAAACCTTCGGACGGCATTGC
CGCAGCTTCAAAAAGCCGCCAAAGCCGCCGCCGCGCTGGACGTGTTGTCCACATTTTCAGCCTTGGCAAAAGAGCGGAAC
TTTGTCCGTCCCGAGTTTGCCGACTATCCGGTTGTCCACATCGAAAACGGCCGCCATCCCGTTGTCGAACAGCAGGTACG
CCACTTCACAGCCAACCACACCGACCTCGACCACAAACACCGCCTCATGCTGCTCACCGGCCCCAATATGGGCGGCAAAT
CCACCTATATGCGCCAAGTCGCGCTGATTGTTTTATTGGCACACACCGGCTGTTTCGTGCCTGCCGATGCCGCCACAATC
GGGCCTGTCGATCAAATCTTCACCCGCATCGGCGCATCGGACGACCTCGCCTCCAACCGCTCCACCTTCATGGTCGAAAT
GAGCGAAACCGCCTACATCCTGCATCACGCCACCGAACAAATCATTGTTTTAATGGACGAAGTCGGACGTGGTACTTCCA
CTTTCGACGGCCTCGCCCTCGCGCACGCAATCGCCGAACACCTGCTGCAAAAAAACAAATCCTTCAGCCTGTTTGCCACC
CACTATTTCGAGCTGACCTACCTGCCCGAAGCCCACGCCGCCGCCGTCAATATGCACCTTTCCGCGCTCGAACAGGGACG
GGACATCGTGTTCCTGCACCAAATCCAACCCGGTCCCGCCGGAAAAAGCTACGGCATCGCCGTCGCCAAACTCGCCGGCC
TGCCTGTGCGCGCATTGAAAGCCGCCCAAAAGCATTTGAACGGACTGGAAAACCAAGCCGCCGCAAACCGTCCCCAACTG
GATATTTTCAGTACCATGCCGTCTGAAAAAGGAGATGAACCGAATGTGGACTGCTTTGTGGATAAAGCAGAGGAAAAACA
TTTTGAAGGTATATTGGCAGCAGCCCTGGAAAACCTCGATCCCGACAGCCTGACCCCGCGCGAAGCATTGTCAGAACTGT
ACCGTCTGAAAGATTTGTGCAAATCCGTATCTTAA

Protein sequence :
MSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYELFLDDAVEAAKLLDITLTTRGQMDGVPIKMAGVPFHAAEQYLARLV
KLGKSVAICEQVGEVGAGKGPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTADK
LNDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDSKEHAVSIGAAGALLNYI
RLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKTPTLFSILDGCATHMGSRLLALWLHHPLRNRAHIRAR
QEAVTALESQYEPLQCHLKSIADIERIAARIAVGNARPRDLASLRDSLFELAQIDLSATGSSLLETLKAVFPETLPVAET
LKAAVMPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAP
ADYQRRQTLKNAERFITPELKAFEDKVLTAQDQALALEKQLFDGVLKNLRTALPQLQKAAKAAAALDVLSTFSALAKERN
FVRPEFADYPVVHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATI
GPVDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQIIVLMDEVGRGTSTFDGLALAHAIAEHLLQKNKSFSLFAT
HYFELTYLPEAHAAAVNMHLSALEQGRDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKAAQKHLNGLENQAAANRPQL
DIFSTMPSEKGDEPNVDCFVDKAEEKHFEGILAAALENLDPDSLTPREALSELYRLKDLCKSVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 4e-167 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NGK_2322 YP_002002947.1 DNA mismatch repair protein MutS VFG0562 Protein 2e-177 49