Gene Information

Name : NGK_2195 (NGK_2195)
Accession : YP_002002820.1
Strain : Neisseria gonorrhoeae NCCP11945
Genome accession: NC_011035
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1819815 - 1821830 bp
Length : 2016 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
GTGGGGAGTTTTCACGGATTCTGTCTTTCAGACGGCATTGGTTTTCAAATGCCGTCTGAAAACGCAAAACGCTCCTGTTT
CTTTATTCTAAACGAGAAAACAGGAGCATTTTTTATGACTACGCCAAAAAAAACCGCCAAAACTTCCGGCAACGAAGCGC
GCGAACTTTCCGACTTGAGCGAAGACATCGGCATCCGCTTCAAATATCAGAACTCCGAACGCGTGTATCTGCAAGGCAGC
CGCGACGACATCCGCGTGCCTTTGCGCGAAATCCGTCAGGACGACACCTACACGGCGCAAGGTACGGAAGCCAACCCGCC
TATTCCGGTGTACGACACCAGCGGCGCATACGGCGATCCGGCGGCGCACATCGACCTGAAACAAGGCCTGCCGCACATCC
GCACGGCGTGGCTGGACGAACGCGGCGATACCGAAATCCTGCCCAAGCTCTCCAGCGAATACGGCATCGAACGTGCGCAC
GATCCGAAAACCGCCCATCTGCGCTTCAACCAAATCACCCGCCCGCGCCGTGCCAAAGCCGGCCGCAATGTAACCCAGCT
CCATTACGCCCGCCAAGGCATTATCACGCCCGAAATGGAGTTCGCCGCCATACGCGAACGCATGAAGCTGGACGAGCTTT
TCAGACGGCCTGAATACGCCAAGCTCTTGAAACAGCACACAGGGCAAAGTTTCGGTGCGAACATCCCGACCCGTCCCGAC
CAAATCACGCCCGAATTCGTGCGCCAAGAAATCGCCGCCGGACGCGCGATTATCCCCGCCAACATCAACCACCCCGAACT
CGAACCGATGATTATCGGCCGCAACTTCCGCGTCAAAATCAACGGCAACTTGGGCAATTCCGCCGTAACCTCCAGCCTGA
CCGAAGAAGTCGAAAAAATGGTGTGGTCGCTGCGTTGGGGCGCGGACACGATTATGGACTTATCCACAGGCGCGCACATC
CACGAAACGCGCGAATGGATTATCCGCAACGCGCCCGTCCCCATCGGCACAGTGCCGATTTACCAAACTTTGGAAAAAAC
CGGCGGCATCGCCGAAGATTTGACTTGGGATTTGTTCCGCGACACCTTAATCGAGCAGGCGGAACAAGGCGTGGACTATT
TCACCATACACGCGGGCGTGTTGCTGCGTTATGTGCCGATGACCGCCAACCGCCTCACCGGCATCGTATCGCGCGGCGGT
TCGATTATGGCGAAATGGTGTTTGGCACATCATCGGGAAAACTTCCTCTACACGCATTTCGACGAAATCTGCGAAATCAT
GAAGGCGTATGACGTATCGTTCAGCTTGGGCGACGGCCTGCGCCCCGGCTGCATTGCCGATGCCAACGACGAATCCCAAT
TCGCCGAATTGCACACCTTGGGCGAATTGACCGATAAAGCGTGGAAACACGACGTACAAGTCATGATCGAAGGCCCCGGC
CATGTGCCGCTGCAACGCGTCAAAGAAAATATGACCGAAGAGTTGCAACACTGCTTTGAAGCACCGTTTTACACACTCGG
CCCGCTCGTTACCGACATCGCCCCCGGCTACGACCACATCACTTCGGGCATAGGCGCGGCCAATATCGGCTGGTACGGCA
CGGCGATGCTTTGTTACGTTACCCCCAAAGAACATTTGGGGCTGCCCGACAAAGAAGACGTGCGCACCGGCATCATCACC
TACAAACTCGCCGCCCACGCCGCCGACCTCGCCAAAGGCTGGCCGGGCGCGCAATTACGCGACAACGCCCTGAGCAAGGC
GCGTTTCGAATTCCGCTGGCGCGACCAATTCCGCTTAAGCCTCGACCCCGAACGCGCCGAGAGCTTCCACGACGAAACCC
TGCCCGCCGAAGGCGCGAAAATCGCCCATTTTTGCTCAATGTGCGGCCCCAAATTTTGCTCGATGAAAATCACGCAGGAA
GTGCGCGACTACGCCGACAAGCAAAAAGCCCAACGGCAGGGTATGGAGGAAAAAGCGGTCGAGTTCGTCAAAAAAGGCGC
GAAGATTTACAGTTGA

Protein sequence :
MGSFHGFCLSDGIGFQMPSENAKRSCFFILNEKTGAFFMTTPKKTAKTSGNEARELSDLSEDIGIRFKYQNSERVYLQGS
RDDIRVPLREIRQDDTYTAQGTEANPPIPVYDTSGAYGDPAAHIDLKQGLPHIRTAWLDERGDTEILPKLSSEYGIERAH
DPKTAHLRFNQITRPRRAKAGRNVTQLHYARQGIITPEMEFAAIRERMKLDELFRRPEYAKLLKQHTGQSFGANIPTRPD
QITPEFVRQEIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDLSTGAHI
HETREWIIRNAPVPIGTVPIYQTLEKTGGIAEDLTWDLFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGG
SIMAKWCLAHHRENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPG
HVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYVTPKEHLGLPDKEDVRTGIIT
YKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQE
VRDYADKQKAQRQGMEEKAVEFVKKGAKIYS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 98
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72