Gene Information

Name : thyA (NGK_1590)
Accession : YP_002002215.1
Strain : Neisseria gonorrhoeae NCCP11945
Genome accession: NC_011035
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 1322183 - 1322983 bp
Length : 801 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGATGATGAAGGCCTATTTGGACTTGATGCGCCACGTCCTCGACAACGGTACGGACAAATCAGACCGCACCGGTACGGG
TACGCGCTCCGTATTCGGTTATCAGATGCGTTTTGACTTGGGCAAAGGTTTTCCGCTGCTGACGACCAAAAAGCTGCATT
TGCGCTCGATAATCCACGAGCTGCTTTGGTTCCTCAAAGGCGATACCAATATCAAATACCTGAAGGATAACAATGTTTCC
ATTTGGGACGAGTGGGCGGACGAAAACGGCGACTTGGGTCCGGTTTACGGCTACCAATGGCGCAGCTGGCCCGCGCCCGA
CGGCAGGCATATCGACCAAATCGCCAATGTGGTGGAACAAATTAAGAAAAACCCCGACTCGCGCCGCCTGATTGTGTCGG
CGTGGAATCCGGCTTTGGTCGATGAGATGGCCTTGCCGCCCTGCCACGCGCTGTTTCAGTTTTACGTTGCCGACGGCAAA
CTGTCCTGCCAGCTTTACCAGCGTAGTGCAGATATTTTCCTTGGTGTGCCGTTTAATATTGCCAGCTACGCGCTGTTGAC
GATGATGATGGCGCAAGTGTGCGGGCTGGAGGCGGGCGAGTTTGTCCATACGTTTGGCGACGCGCATTTGTACCGTAACC
ATTTCGAACAGGCCGCATTGCAGTTGGAACGCGAACCGCGCGCCTTGCCTGTGATGAAAATCAATCCTGAAGTCAAGGAT
TTGTTTGCCTTCAAGTTTGAAGATTTCGAGTTGGAAGGCTACGATCCGCATCCGCACATCAAGGCGGTAGTGTCGGTTTA
G

Protein sequence :
MMMKAYLDLMRHVLDNGTDKSDRTGTGTRSVFGYQMRFDLGKGFPLLTTKKLHLRSIIHELLWFLKGDTNIKYLKDNNVS
IWDEWADENGDLGPVYGYQWRSWPAPDGRHIDQIANVVEQIKKNPDSRRLIVSAWNPALVDEMALPPCHALFQFYVADGK
LSCQLYQRSADIFLGVPFNIASYALLTMMMAQVCGLEAGEFVHTFGDAHLYRNHFEQAALQLEREPRALPVMKINPEVKD
LFAFKFEDFELEGYDPHPHIKAVVSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-82 64