Gene Information

Name : guaA (Cpar_1868)
Accession : YP_001999460.1
Strain : Chlorobaculum parvum NCIB 8327
Genome accession: NC_011027
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2053302 - 2054852 bp
Length : 1551 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCAACAACCCTTCAATCGGTCATCGTCCTCGACTTCGGGTCTCAGTACACCCAGCTCATCGCGCGTCGCATCCGTGA
AATCGGCATCTACTCCGAGATTTTTCCCTACCACACCAGCGCCGAGGAGCTGAAAAAACACCAGCCGAAAGCGATCATCC
TTTCCGGCGGCCCGAACAGCGTGTACGACGAAACCGCCTTCATGCCCGATCCGGAGGTGTTCAGCCTCGGCGTGCCGGTG
CTCGGCATCTGCTATGGCCTGCAAGCAATCGCCAAGCACTTCGGCGGCAACGTCGAAAGCTCGTCGAAGCAGGAGTTCGG
CCGCGCCAAGATGCTGGTGAGCCACGACGAGCGCGAGAGCATGCTGTTCAAGGACATTCCGGACTCGGACGTCTGGATGA
GCCACGGCGACAAGGTGACCAAACTGCCCGACGGCTTCCGCGTTACAGCCAGCACGGCCAATGCCGAGATGTGCGCCATC
GAGAGCTTCGGCAGCAAGGCTGCGCTGAAGGTGTTCGGCTTGCAGTTCCACCCTGAGGTGCAGCACTCGCTCTACGGCAA
GCAGCTCCTTTCGAACTTCCTGATCGACATCGCGGGCATCACGCCCGACTGGTCGCCGAAGAGCTTTATCCAGCACCAGA
TCGAGGAGATCAAGCGGGTTGCGGGCGACTCGACCGTGGTGTGCGGCATCAGCGGCGGCGTCGATTCCACGGTGGCTGCC
GTGCTGGTCAGCAAAGCGATTGGCGACAAGCTGCACTGCGTCTTTGTGGATAACGGCCTGCTCCGAAAGGACGAAGCGAC
AAAGGTGATGGAGTTCCTCAAGCCGCTCGGCCTGAAGGTGACGCTCGCCGACGCCAGCGACCTCTTTCTGGGACGACTCA
AAGGCGTGGCTTCGCCGGAGAAGAAGCGCAAGATCATCGGCCGCACCTTCATCCGCGTGTTTGAAGAGAACATCCACGAC
GAGAAGTTCCTCGTGCAGGGCACGCTCTACCCGGACGTCATCGAGAGCGTCAGCGTCAAGGGGCCGTCTGAAACCATCAA
GTCGCACCACAACGTCGGCGGCCTGCCGAAGCGCATGAAGCTCAAGCTCATCGAGCCGCTGCGCGAGCTGTTCAAGGACG
AAGTCCGCGCCGTCGGACGCGAGCTTGGCATCGCCGAGGACATCCTGATGCGCCACCCCTTCCCCGGCCCTGGCCTCGCC
GTGCGCGTGCTCGGCTCGTTGACGAAGGAGCGCCTCGACGTGCTGCGCGAAGCCGACCAGATTTTCATCGACGAACTCAA
AGAGAGCGGCTTGTACCAGAAAGTGTGGCAGGCCTTCTCGGTGCTCCTGCCGGTGCAGTCGGTTGGCGTCATGGGCGACA
AACGCACCTACGAAAACGTCCTCGCATTGCGCGCCGTCGAATCCACCGACGGCATGACCGCCGACTGGGCGCATTTGCCG
CACGACTTCCTCTCAAAAGTCTCGAACCGAATCATCAACGAAGTCCGAGGCATCAACCGCGTGGCGTACGATATTTCGTC
CAAGCCACCGGCGACGATCGAGTGGGAGTAA

Protein sequence :
MATTLQSVIVLDFGSQYTQLIARRIREIGIYSEIFPYHTSAEELKKHQPKAIILSGGPNSVYDETAFMPDPEVFSLGVPV
LGICYGLQAIAKHFGGNVESSSKQEFGRAKMLVSHDERESMLFKDIPDSDVWMSHGDKVTKLPDGFRVTASTANAEMCAI
ESFGSKAALKVFGLQFHPEVQHSLYGKQLLSNFLIDIAGITPDWSPKSFIQHQIEEIKRVAGDSTVVCGISGGVDSTVAA
VLVSKAIGDKLHCVFVDNGLLRKDEATKVMEFLKPLGLKVTLADASDLFLGRLKGVASPEKKRKIIGRTFIRVFEENIHD
EKFLVQGTLYPDVIESVSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIAEDILMRHPFPGPGLA
VRVLGSLTKERLDVLREADQIFIDELKESGLYQKVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESTDGMTADWAHLP
HDFLSKVSNRIINEVRGINRVAYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-134 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-134 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-134 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-127 51