Gene Information

Name : tpx (Cpar_1318)
Accession : YP_001998921.1
Strain : Chlorobaculum parvum NCIB 8327
Genome accession: NC_011027
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 1430962 - 1431462 bp
Length : 501 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCAACAATTACCCTGAAAGGTAATTCCATCAATACTGCCGGTGAGCTTCCGGCAGTCGGCAGTCAGCTTCCTGCATT
CACTCTTGTGAAAAGCGATCTGTCTGAAGTAACCCAGGCCGATTTTGCAGGCAAAAAGGTTGTGCTGAACATTTTTCCGA
GCCTCGATACGGCTGTTTGCGCTGCATCGGTGAGGCGTTTCAACAAGGAAGCCGGTGAGCGCGGTGATACGGTTGTACTT
TGCATCTCCGCCGATCTGCCGTTCGCGCAGGGCCGTTTCTGCACCACTGAGGGACTTGAAAATGTGGTGTCGCTTTCAGT
ATTCCGTTCGCCCGAGTTCGGTGGCGATTACGGCCTGACCATCACCGACGGCCCGCTGAAAGGCCTGCTTTCACGCGCGG
TGATCGTCGCCGACGCCGCAGGCAAGGTGCTTTACACCGAACAGGTGCCCGAGATCGTGCAGGAGCCTGATTACGATAAA
GCGCTTGCGGCGCTCGCCTGA

Protein sequence : 
MATITLKGNSINTAGELPAVGSQLPAFTLVKSDLSEVTQADFAGKKVVLNIFPSLDTAVCAASVRRFNKEAGERGDTVVL
CISADLPFAQGRFCTTEGLENVVSLSVFRSPEFGGDYGLTITDGPLKGLLSRAVIVADAAGKVLYTEQVPEIVQEPDYDK
ALAALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-38 48
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-38 48
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-38 48
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-38 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_001998921.1 thiol peroxidase VFG0087 Protein 5e-39 48