Gene Information

Name : lysS (Ctha_0242)
Accession : YP_001995160.1
Strain : Chloroherpeton thalassium ATCC 35110
Genome accession: NC_011026
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 288734 - 290287 bp
Length : 1554 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCGAATCAGCCAACCAAGCCGGTGCAGTCCGAAGAAAACGCAGAACACTTGAGCCAGCAAGCTCAGGAAGAATTAAA
TGACCAAATGCTGCGCCGCCGCGAAGAGCTTGAAAAACTTCGCGAAATGGATGTAAATCCGTATCCATATAGTTTTGAAG
TCACTCACACAGGCAAACAAATCATAGAGAATTTTAAAGACGACGAAAAAGCAGCGGTCGCCATTGCCGGCAGAATTATG
TCCATTCGCAAAATGGGCAAAGCCTCGTTTTTCCATGTGCAAGATGCCTCCGGCAGAATTCAAGTTTACATCAAAAAGGA
CGAAGTCGGCGAAACGGCTTATCAGGTTTTCAAACTTTTAGACATCGGCGATATTGTTGGCGTCAAAGGCTTTAGCTTCC
GCACAAAAACCGGTGAGGTTTCCGTTCATGCCGAAGCATGTGAATTGCTCTCCAAATCGCTGCGCCCGATGCCTATTGCC
AAACAAAAAGAAGTCGACGGCAAAACCGTTACCTACGACGCGTTCAGCGACAAAGAACTGCGCTATCGCCAACGCTATGT
AGATTTGATTGTCAATCCTGAGGTGAAAACCGTGTTTTTGAAGCGGACAAAAATGATAAATTCCATCCGCAATTTTCTCA
ACGAACGCGGCTACTTGGAAGTCGAAACGCCAATTCTTCAGCCGATTTACGGCGGCGCGTCGGCCAGGCCGTTCGTGACG
CATCACAACACGCTCGACATGCCGCTTTATTTGCGCATCGCCAACGAGCTTTATTTGAAGCGCCTCATCGTCGGCGGCTT
CGACGGCGTTTATGAGTTCGCGAAGGATTTCAGAAACGAAGGCATGGACAGATTCCACAACCCGGAATTCACGCAAATCG
AGCTGTATGTCGCTTATAAAGATTATGCGTGGATGATGAACTTGGTTGAGGAAATGCTTTCAAAAACGGCGGAAGCCGTG
AACGGCTCAACTGTCGTAGAATTTGCCGGCCATAAAATCGACTTGAAACCACCGTTCAAGCGCATGACCATCACGGATTC
GATTAAGGAATACACCGGCAAAGACATCGATGGCAAGTCGGAAGCCGAACTTCGCCAAATCGCAAAAGAGTTGGGCATTG
AGATTGAGGCAAATTTAGGCAGCTCGAAAATCATCGATGAAATTTTCGGCGAATATGTCGAGCCGAAGCTCATCGACCCG
ACATTTATCATGGACTATCCGGTGGAAATGTCGCCGCTGGCGAAAAAGCATCGCGAGAAACCCGGATTTGTGGAGCGATT
TGAACTCATTGCCGCTGGAAAAGAAATCTGCAATTCCTTCTCGGAACTCAACGATCCGCTCGACCAGCGCGCCAGATTGG
AAGAGCAAGCCAGCCTGCGTGCCAGAGGCGACGACGAAGCGATGGCGGTCGACGAGGATTTCCTTCGCGCGTTGGAATAC
GGCATGCCGCCTTGCGCCGGTCTCGGCATCGGCATCGACCGTTTGGCCATGATTTTAACTGGACAAGAGTCTATTCGCGA
CGTGCTCTTTTTTCCGCAAATGAAGCCAGAATAA

Protein sequence :
MSNQPTKPVQSEENAEHLSQQAQEELNDQMLRRREELEKLREMDVNPYPYSFEVTHTGKQIIENFKDDEKAAVAIAGRIM
SIRKMGKASFFHVQDASGRIQVYIKKDEVGETAYQVFKLLDIGDIVGVKGFSFRTKTGEVSVHAEACELLSKSLRPMPIA
KQKEVDGKTVTYDAFSDKELRYRQRYVDLIVNPEVKTVFLKRTKMINSIRNFLNERGYLEVETPILQPIYGGASARPFVT
HHNTLDMPLYLRIANELYLKRLIVGGFDGVYEFAKDFRNEGMDRFHNPEFTQIELYVAYKDYAWMMNLVEEMLSKTAEAV
NGSTVVEFAGHKIDLKPPFKRMTITDSIKEYTGKDIDGKSEAELRQIAKELGIEIEANLGSSKIIDEIFGEYVEPKLIDP
TFIMDYPVEMSPLAKKHREKPGFVERFELIAAGKEICNSFSELNDPLDQRARLEEQASLRARGDDEAMAVDEDFLRALEY
GMPPCAGLGIGIDRLAMILTGQESIRDVLFFPQMKPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-102 46
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 9e-81 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001995160.1 lysyl-tRNA synthetase VFG1668 Protein 1e-102 46