Gene Information

Name : Ctha_1959 (Ctha_1959)
Accession : YP_001996860.1
Strain : Chloroherpeton thalassium ATCC 35110
Genome accession: NC_011026
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2335244 - 2336677 bp
Length : 1434 bp
Strand : +
Note : KEGG: csc:Csac_1831 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence :
ATGAAACGTACAAAAATCATTTGTACACTTGGCCCTTCAACCGATTCAATTGAAAAAATCGTCGATCTGATCAATGAAGG
GATGGATGTTGCCCGCTTGAATTTTTCTCACGGAACAAGAGAAGAGCAAGAACAGCGAATTCAGCTTGTTCGAAAAGCCT
CTGAACTAACCGGAAAAGCTGTTGCGATTCTTCAAGATTTGCAAGGGCCGAAAATTAGAATTGGCGATTTAGCCAAAACG
GTGCTGTTAAATCAAGGCGAGCAGCTGAGAATCTCGACGGAGGAGCAGCTTGGCAATTACGAAGTCGTTTCTACGAGCTA
CAAGGAAATTGTCAACGATGTTAATCCCGGCGATACAATTTTGATGGACGACGGGCGAATTGAATTGAAAGTGATTTCGA
AAACCGCAACCGAAGTGGTTACTGAGATTGTCATTGGTGGATTGCTCAAGCCGAAAAAAGGCTTGAATTTGCCCGGCGTT
AATATTTCCATTCCGTCGCTTACGGAAAAAGACCTGGAAGATTTGGATTTCGGTTTGGCGCATGATGTCGACATGGTGGC
GCTTTCCTTTGTTCGATCGGCCAACGATGTGAAGCGCATCAAGCAACTCATTCACGAAAAGAACAAGGACGTTTGGGCAA
TTGCCAAAATCGAAAAGCCGGAAGCCGTCGCTAATATCGATGCGATTATTTTGGAATCGGATGGCGTCATGGTGGCGCGT
GGCGATTTGGGCATCGAGATGCGTACCGAAGAAGTGCCGGTGTTGCAAAAGATGATTGTGGAAAAATGCAGTTTAGCGCA
TAAGCCGGTGATTATTGCCACGCAAATGTTGGAGTCGATGATTGAAAATCCGCGTCCGACTCGCGCGGAGGCGAACGATG
TGGCCAATGCCGTTTTTGATGGCACAGATGCGGTGATGCTTAGCGGCGAAACCGCTGCCGGAAATTTTCCGGTTGAAGCC
GTGCGAACCATGCGAGAAATTATCGAGCGAGTTGAAAAACAAGGTCTCACGCATATTCCCGTAAGGCAAAAACAATGGAT
GCAAGCGTGTTCGCCTCGCATTCGCTGCATCGATTTGGATGAAGCCATTGCGGCCTCTGCGGTTCAAATTGCGGAATCCT
TGTTAGCCAAAGCGATTATTGTTTTGACTCACAGTGGCGCAACTGCCGTGAAAATTTCCAAGCAAAAGCCAAAGTGCGCA
GTGATTGCGGTTTCGGACAAAGAGGAAGTTCAGCGATGGATGTGCATGGTGTGGGGGATAAATACCATTGTCACAGAAAC
GATGGTTTCCACAGACGAAAGCTTCAGAAAAATTGAGAAAATATTGCGAGAAAACGGCGTCGTTAAAACAGGTGACCTTG
TGGTCTACACTTTAGGTATTCCCATTCTTGATCACGGCGGAACGGACACCATAAAAGTTAGTCACGTCAACTAA

Protein sequence :
MKRTKIICTLGPSTDSIEKIVDLINEGMDVARLNFSHGTREEQEQRIQLVRKASELTGKAVAILQDLQGPKIRIGDLAKT
VLLNQGEQLRISTEEQLGNYEVVSTSYKEIVNDVNPGDTILMDDGRIELKVISKTATEVVTEIVIGGLLKPKKGLNLPGV
NISIPSLTEKDLEDLDFGLAHDVDMVALSFVRSANDVKRIKQLIHEKNKDVWAIAKIEKPEAVANIDAIILESDGVMVAR
GDLGIEMRTEEVPVLQKMIVEKCSLAHKPVIIATQMLESMIENPRPTRAEANDVANAVFDGTDAVMLSGETAAGNFPVEA
VRTMREIIERVEKQGLTHIPVRQKQWMQACSPRIRCIDLDEAIAASAVQIAESLLAKAIIVLTHSGATAVKISKQKPKCA
VIAVSDKEEVQRWMCMVWGINTIVTETMVSTDESFRKIEKILRENGVVKTGDLVVYTLGIPILDHGGTDTIKVSHVN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-71 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-71 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-71 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-70 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ctha_1959 YP_001996860.1 pyruvate kinase VFG0479 Protein 4e-71 42