Gene Information

Name : guaA (Ctha_1118)
Accession : YP_001996029.1
Strain : Chloroherpeton thalassium ATCC 35110
Genome accession: NC_011026
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1313300 - 1314844 bp
Length : 1545 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAATTCCGTGATTGTTCTCGATTTCGGATCCCAGTACACGCAGCTCATTGCCCGGCGCATTCGGGAACTGGGAATCTA
TTCCGAAATCCTGCCTTACCATACATCAGCCGAGGCGCTCCGCGAGCGAAATCCGAAAGCACTGATTCTCTCCGGCGGAC
CGACCAGCGTTTATGACGCATTTGCCCCCATGCCCGACGAAAAAATTTACGAGCTGGACATTCCCATTTTGGGAATTTGC
TACGGCCTTCAAGCCATTGCAAAGCATTTTGGTGGCGAAGTTGCCGCTTCACCAAAACGCGAATTTGGCCGCGCTCAAAT
GAACATTGTTCGCCAAAATGAGTTAGCGGAAAGTTTACTTTTCAAAAATATACCAGACTCCACCGTTTGGATGAGCCACA
GCGATAAACTCACTTGCCTGCCCAAAGGATTTCACATCACAGCCCAAACTGCAAACTCCGAACTTTGCGCCATTGAAGTC
ACTGAAGGCGAAGGTGCACACCGGATTTTTGGCCTGCAATTTCATCCAGAAGTGCATCACACGGAGTTTGGCGAAAAGCT
GCTATCTAACTTTCTCATCAACATCGCTGGCATCACGCCGGATTGGTCGCCACAAAGTTTCATCGATTCTGAAATTGCCC
GCATAAAAGAACTTGTCGGCGATCAAACAGCCATTTGCGCCATCAGCGGCGGCGTTGATTCATCCGTTGCAGCCGTTTTG
GTCAGCCGGGCGTTGGGCGATAAACTTCATTGCATTTTTGTGGATAATGGCTTGCTGAGAAAAAATGAGGCCGAAAAAGT
TCAAGAAAAATTAAAACAGCTTGGCTTAAATCTAACAACCGTCGACGCGTCCGAGCTCTTTTTAAGCCGCCTGAAAAATG
TGGTTTCGCCGGAGCGCAAGCGAAAAATCATCGGCAGGACATTCATCAAAGTTTTTGAGGAGCACATTCACAACGAAAAG
TTTTTGGTGCAAGGCACGCTTTATCCAGATGTAATTGAAAGCGTGAGCGTGAAAGGGCCGTCGCAAACGATTAAAACGCA
TCATAATGTTGGCGGATTGCCAAAGCGCATGAAACTTAAGTTGATCGAGCCGCTGCGCGAGCTTTTCAAAGATGAAGTTC
GGAAAGTGGGAAAATTGCTTGATGTGCCAGATGAGATTTTAACCCGCCATCCATTTCCGGGTCCCGGGCTTGCGGTGCGT
GTGCTTGGCTCGGTTTCCAAAGAACGACTGGATGTCTTGCGCGAAGCCGATGCGATTTTCATCGACGAACTGAAAAAACA
TGACCTTTACTTGCAAATTTGGCAGGCATTCACAGTGCTGCTGCCAGTTCAAACCGTCGGCGTGATGGGCGACAATCGCA
CTTATGAAAACGCGGTTGCCTTGCGCGCGGTCAATTCCACCGATGGCATGACAGCAGACTGGGCGCGGTTGCCGAACGAT
TTCTTGGCTCATGTATCGAACCGAATCATCAATGAAGTTCGTGGGATCAATCGCGTCACCTACGACATTTCATCTAAACC
GCCGGCAACAATTGAGTGGGAATAA

Protein sequence :
MNSVIVLDFGSQYTQLIARRIRELGIYSEILPYHTSAEALRERNPKALILSGGPTSVYDAFAPMPDEKIYELDIPILGIC
YGLQAIAKHFGGEVAASPKREFGRAQMNIVRQNELAESLLFKNIPDSTVWMSHSDKLTCLPKGFHITAQTANSELCAIEV
TEGEGAHRIFGLQFHPEVHHTEFGEKLLSNFLINIAGITPDWSPQSFIDSEIARIKELVGDQTAICAISGGVDSSVAAVL
VSRALGDKLHCIFVDNGLLRKNEAEKVQEKLKQLGLNLTTVDASELFLSRLKNVVSPERKRKIIGRTFIKVFEEHIHNEK
FLVQGTLYPDVIESVSVKGPSQTIKTHHNVGGLPKRMKLKLIEPLRELFKDEVRKVGKLLDVPDEILTRHPFPGPGLAVR
VLGSVSKERLDVLREADAIFIDELKKHDLYLQIWQAFTVLLPVQTVGVMGDNRTYENAVALRAVNSTDGMTADWARLPND
FLAHVSNRIINEVRGINRVTYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-130 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-130 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-130 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-124 49