Gene Information

Name : pyk (MARTH_orf034)
Accession : YP_001999704.1
Strain : Mycoplasma arthritidis 158L3-1
Genome accession: NC_011025
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 36040 - 37458 bp
Length : 1419 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAAATACAATAAACAAAGAACGAAAATTGTCGCAACAATTGGTCCTTCTTCAAATACTTATGATGTTATGAAACAATT
AGTCGAAGCTGGAGTTACTACTATTAGAGTGAATTTTTCACATGGTGATGAAGAAATTCATACTAATGTTTATAACTTAG
CAAGAGAAGTTTCTCGTGAACTAAATGTTCCAATTTCTTTACTTTTAGATACTAAGGGCCCTGAAATTAGAATTGGCAAA
ATGAAAGATGATGCTTGCTTACTTAAAAAAGGTAGCATCGTAACTATCAAAACAGATGAAAATTCTTATAAAAATTTAGT
TGGCGATGATAAAGTGATCACTGTTTCATATCGCATGGATAAAGATATGCATGTAGGTGCAAAAGTTTTATTAGATGATG
GCAAATTAGTGACAATCGTTAAAGAAATCAAGCCTGAAATTATTTTAGTAGAAGTGCAAAATGACCATGTTCTAAAAACT
AATAAAAGAGTGAATATTCCTGGAATTGATTTTTCAATGCCTTTTATGTCGCCTAAGGATCGTGAAGACATTATTTGAGG
TGCTAAATATGGCGTTGATTTCATTGCCGCTTCTTTTGTGAATAGTGCTAAAAATGTTCATGAAATCCGTGAAATTTTAA
AACAAGCAAATGCTGAACACATTCAAATTTGTTCAAAGATTGAATCACAAACCGGAATTGACAATATTGACGAAATTATT
GAAGCTAGTGATTCAATTATGATTGCTCGTGGTGATTTAGGTCTTGAAATTCCTTACTACGAAGTGCCATATTGAGAGAA
AAAAATTATTGCCAAATGTCGCAAAGCAAACAAAGAAGTAATTGTTGCAACCCAAATGCTTGATTCTATGGAAAAAACGC
CGCTTCCTACAAGAGCAGAGATTAGTGATGTTTATTGGGCTACTGAATTGGGTGCTTCTGCTACTATGACCTCTGGTGAA
ACTGCTAGTGGACAATATCCAGTTGAAGCAATTAAAACGATGGCAACAATAAATCATCGTGCTGAACAAGAATATTTCAA
TGAAATAGCAACTTCATGTAACTGCCAATGCCAACCAAAATGTGAGCTTGGACATGTTGCTAAAGAACTTAAAGAAAAAA
CAAAAACTGGCGATTTTCCATATACTATTGCTATTTCAGAAGATGGCAAATTATTGAAAAAAATTGCCAAATATAAACCA
AATACTACTGTAATTGCATTGGTTAGCGATCCGAAGATTGAAACTGCTTTCGGAATCACTTTCGGAATCTTTTGTGAAAA
AAATGGTGCTAAAGCAATTGAAAAAGTCATAAAGGATCCTAAGTACTTGAATGAAATTTTGGCTTCGCATTTTGATATTA
AAAAAGGTCAAAAATTCTTAGTAATTAAAGATGGTTTAATTTCTGAAAATTCATTGTAA

Protein sequence :
MKYNKQRTKIVATIGPSSNTYDVMKQLVEAGVTTIRVNFSHGDEEIHTNVYNLAREVSRELNVPISLLLDTKGPEIRIGK
MKDDACLLKKGSIVTIKTDENSYKNLVGDDKVITVSYRMDKDMHVGAKVLLDDGKLVTIVKEIKPEIILVEVQNDHVLKT
NKRVNIPGIDFSMPFMSPKDREDIIWGAKYGVDFIAASFVNSAKNVHEIREILKQANAEHIQICSKIESQTGIDNIDEII
EASDSIMIARGDLGLEIPYYEVPYWEKKIIAKCRKANKEVIVATQMLDSMEKTPLPTRAEISDVYWATELGASATMTSGE
TASGQYPVEAIKTMATINHRAEQEYFNEIATSCNCQCQPKCELGHVAKELKEKTKTGDFPYTIAISEDGKLLKKIAKYKP
NTTVIALVSDPKIETAFGITFGIFCEKNGAKAIEKVIKDPKYLNEILASHFDIKKGQKFLVIKDGLISENSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-60 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-60 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-59 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-61 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_001999704.1 pyruvate kinase VFG0479 Protein 9e-61 42