Gene Information

Name : thyA (Rpal_4007)
Accession : YP_001992978.1
Strain : Rhodopseudomonas palustris TIE-1
Genome accession: NC_011004
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 4293858 - 4294652 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGATCCAATATCAGGACCTGCTCGAACGCATCTTGAGCGACGGGGCCGAAAAGCACGACCGCACTGGCACCGGCACGCT
GTCGGTATTCGGGCATCAGATGCGGTTCGACCTCGCCGCCGGCTTTCCGATGCTGACCACCAAGCGGCTGCCGCTGAAGG
CGATTGTGCACGAGCTGCTATGGTTCCTGCAGGGCGATACCAACATCAAATACCTGCACGATCACGGCGTCACGATCTGG
GACGAGTGGGCGGACGCCAACGGCGATCTCGGCCCGGTGTACGGCGCACAGTGGCGCTCGTGGCCGACCGCGGATGGTGG
CTCGATCGATCAGATCGCCAATGTGGTCGAGATGATCAAACGTAATCCGGACTCGCGGCGGCTGATGGTGACGGCGTGGA
ATCCGGCTGACGTCGAGAAGATGGCGCTGCCGCCGTGCCACTGCCTGTTCCAGTTCTATGTCGCGAACGGCAAGCTGTCG
TGTCAGCTGTATCAGCGCTCGGCCGACGTTTTTCTCGGCGTGCCGTTCAACATCGCATCGTACGCGCTGCTGACGCTGAT
GGTGGCGCAAGTCACTGGTCTAAAGCCCGGCGAGTTCGTCCACACCCTTGGCGACGCGCACCTGTATTCCAATCACCTGG
AGCAGGCGCGGCTGCAACTGACCCGTGCCCCGCGCGCGCTGCCGGTGATGACGATCAATCCGGCGGTGAACGACATCTTC
GGCTTCCGCTACGAGGATTTCACCCTGACCGGCTACGATCCGCATCCGCACATCAAGGCCGAGGTGGCGGTGTGA

Protein sequence :
MIQYQDLLERILSDGAEKHDRTGTGTLSVFGHQMRFDLAAGFPMLTTKRLPLKAIVHELLWFLQGDTNIKYLHDHGVTIW
DEWADANGDLGPVYGAQWRSWPTADGGSIDQIANVVEMIKRNPDSRRLMVTAWNPADVEKMALPPCHCLFQFYVANGKLS
CQLYQRSADVFLGVPFNIASYALLTLMVAQVTGLKPGEFVHTLGDAHLYSNHLEQARLQLTRAPRALPVMTINPAVNDIF
GFRYEDFTLTGYDPHPHIKAEVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 3e-83 64