Gene Information

Name : guaA (Rpal_2498)
Accession : YP_001991487.1
Strain : Rhodopseudomonas palustris TIE-1
Genome accession: NC_011004
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2696001 - 2697698 bp
Length : 1698 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCGGCGGTTGCGCCGGTCCCCATCGCCGTTTTTCCCCGTTGCGAGCCGGGCTGCGGTCGCGTATCTGCTGCCCATGAC
AGCCCCCAGCACATCCTCCGCTTCGTCCGTCGTCCCCTCCGGCGCCGACACCTCGCCGCACGTCGCTGCGATCCACGAGA
AGATCCTGATCGTCGACTTCGGCTCGCAGGTCACCCAGCTGATCGCCCGCCGCGTCCGCGAGGAGGGCGTGTATTCCGAG
ATCGTGCCGTTCCAGAAGGCGGAGGCCGCCTTCGCCGAGATGAAGCCGAAAGCCGTGATCCTGTCCGGCGGCCCGGCCTC
GGTGCTGGACGACAACGCACCCAGCGCCCCGATGGCGATCCTCGAAGCCGGCGTGCCGGTGCTCGGCATCTGCTACGGCG
AACAGACGCTGGCCAAGCAGCTCGGCGGCACCGTCGAGGGTGGCCACCACCGCGAATTCGGCCGCGCCCAGATCGAGATC
ACCGATGACTGCGCGCTGTTCGACGGTGTCTGGCAGAAGGGCGGCAAATACGACGTCTGGATGAGCCATGGCGACCGCGT
CACCAAGCTGCCCGACGGCTTTCGCGCGGTGGCGCAGGCGCCGGGTTCGCCGATCTCGGTGATCGCCGACGACACCCGCA
AATTCTACGCGATGCAGTTTCACCCCGAAGTGGTGCACACCCCGGACGGCGCCAAGCTGCTGCGCAACTTCGTCCGCAAG
GTCGCTGGGCTGACCGGCGACTGGACAATGCGCGCCTTCCGCGAGGAAGCGATCGAGAAGATCCGCGCCCAGGTCGGCAG
CGGCAAGGTGATCTGCGGCCTATCCGGCGGCGTCGACTCCGCGGTGGCGGCGGTGCTGATCCATGAGGCGATCGGCGATC
AGCTCACTTGCGTGTTTGTCGACCACGGCCTCTTGCGCAAGGACGAGGGCAAGAGCGTCGTCGACCTGTTCCGGCACCAC
TACAACATCCCGCTGGTGCATGTGGATGTGTCCGAGACCTTCCTCGGCGCGCTGAAGGGCGTCACCGATCCGGAGCAGAA
GCGCAAGACCATCGGCAAGCTGTTCATCGACGTGTTCGAGGCCGAAGCCAGACGCGTCGGCGGCGCCGACTTCCTGGCGC
AGGGCACGCTGTACCCGGACGTGATCGAGAGCGTGTCGTTCACCGGCGGCCCGTCGGTGACGATCAAGTCGCATCACAAC
GTCGGCGGCTTGCCCGAACGCATGAACATGAAGCTGGTCGAGCCGCTGCGCGAACTGTTCAAGGACGAAGTCCGCGCATT
GGGGCGCGAGCTCGGGCTGCCCGACGTGTTCGTCGGCCGCCATCCGTTCCCGGGCCCCGGCCTCGCGATCCGCTGCCCTG
GCGAGATCACCGAGGAGAAGCTCGAAATCCTGCGCAATGCGGATGCGGTGTACATCGACCAGATCCGCAAGGCGGGCCTC
TACGATGTCATCTGGCAGGCGTTCGCCGTTCTGCTCCCGGTCCGCACCGTCGGCGTGATGGGCGACGGCCGCACCTACGA
CTACGTCGTCGGCCTGCGCGCCGTGACGTCCACCGACGGCATGACCGCCGACTTCTACCCGTTCGAGATGTCCTTCCTCG
GCGCCACCGCGACGCGGATCATCAACGAGGTCAAGGGCGTCAACCGCGTGGTGTACGACGTCACGTCGAAGCCGCCGGGA
ACGATTGAGTGGGAGTAG

Protein sequence :
MRRLRRSPSPFFPVASRAAVAYLLPMTAPSTSSASSVVPSGADTSPHVAAIHEKILIVDFGSQVTQLIARRVREEGVYSE
IVPFQKAEAAFAEMKPKAVILSGGPASVLDDNAPSAPMAILEAGVPVLGICYGEQTLAKQLGGTVEGGHHREFGRAQIEI
TDDCALFDGVWQKGGKYDVWMSHGDRVTKLPDGFRAVAQAPGSPISVIADDTRKFYAMQFHPEVVHTPDGAKLLRNFVRK
VAGLTGDWTMRAFREEAIEKIRAQVGSGKVICGLSGGVDSAVAAVLIHEAIGDQLTCVFVDHGLLRKDEGKSVVDLFRHH
YNIPLVHVDVSETFLGALKGVTDPEQKRKTIGKLFIDVFEAEARRVGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHN
VGGLPERMNMKLVEPLRELFKDEVRALGRELGLPDVFVGRHPFPGPGLAIRCPGEITEEKLEILRNADAVYIDQIRKAGL
YDVIWQAFAVLLPVRTVGVMGDGRTYDYVVGLRAVTSTDGMTADFYPFEMSFLGATATRIINEVKGVNRVVYDVTSKPPG
TIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-134 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-135 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-135 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-121 51