Gene Information

Name : leuS (LCABL_09490)
Accession : YP_001986894.1
Strain : Lactobacillus casei BL23
Genome accession: NC_010999
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 921652 - 924063 bp
Length : 2412 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGCATACGATCATCATGAGATCGATAAGAAGTGGCAGCGTTATTGGGCCGAGCATAACGAATTTAATACCACAACCGA
TCCTAAGAAGCCGAATTATTATGCGTTGGACATGTTTCCTTATCCGTCAGGCCAAGGCCTGCATGTTGGGCATCCAGAAG
GGTATACGGCAACTGATATTGTTGCACGCATGAAACGGATGCAAGGGTTCAATGTTCTTCATCCTATGGGCTGGGATGCA
TTCGGCTTGCCAGCTGAGCAATATGCCTTGAACACGGGTCACAATCCGAAGACCTTTACCAAACAAAATATTGAGACCTT
TAAGCGTCAAATCAACAGCCTTGGCTTTTCATATGACTGGAATCGTGAAATCAACACAACGGATCCGAATTACTACAAGT
GGACCCAGTGGATTTTTGAACAACTTTATAAACATGGTCTGGCATATGAAGCTGAGGTACCGGTTAACTGGAGTCCGGAT
CTAGGGACGGTTGTTGCAAACGAAGAAGTGATTGATGGCAAAACGGAGCGCGGCGGGTTCCCAGTTGTTCGGAAGCCGAT
GCGTCAGTGGATGCTGAAAATCACAGCCTATGCTGAAAAGCTGTTGACGGATCTGGACGATCTTGACTGGCCGGAATCAA
TTAAGCAGATGCAACGCAACTGGATTGGCAAATCAACTGGGGCACAGATCACCTTCCGGGTAACTGACAGTCATGAGCCG
TTTGATGTCTTTACCACTCGTCCAGATACGCTGTTTGGTGCAACGTATGTCGTGATGGCACCAGAACATGAATTAGTTCA
GAAAATTACCACCCCGGCACAACAGGCAGTCGTTGATGCGTACATTGACGAAGCCGCCCATAAGTCAGATCTTGATCGTA
CCGCTTTAGATAAGGAAAAGACTGGTGTTTGGACCGGGGCCTACGCGACTAATCCGGTTAACGGCGAAAAACTGCCGATT
TGGATTTCAGACTACGTTTTAGCCTCTTATGGGACTGGCGCAATCATGTCCGTGCCTGCGCATGATGATCGTGACTACGC
TTTTGCCAAAAAGTTTGGTATTGAAATCAAGCCTGTTATTGAAGGCGGCAATGTCGATGAAGCAGCTTATACTGGCGATG
GCGTGCACATCAACTCCGGGTTCCTTGATGGTTTGAATGAACACGACGCGATTGATCGAATGATCAAATGGCTTGAAGAT
AAAGGTATCGGCAGTGCCAAGATCAATTACAAACTGCGTGATTGGGTCTTTTCACGCCAGCGTTATTGGGGTGAACCGAT
TCCTGTCATTCACTGGGAAGATGGCGAAACCACGTTGGTACCAGAAGACGAACTGCCCCTCACATTACCTGAAGAGGCTG
ATATCAAGCCAAGCGGTACTGGCGAGAGTCCACTGGCAAATCTGACTGACTGGGTTAATGTGGTCGACAAGAACGGGCGG
AAAGGTAAGCGTGAGACCAATACAATGCCGCAATGGGCAGGGTCTTCATGGTACTTCCTGCGGTTTGTTGATCCTCACAA
CAAGGAAGCTCTTGCGGATTACGACAAACTTAAGGCATGGATGCCAGTTGATCTGTACATTGGAGGGGCTGAACATGCTG
TGCTGCACCTGCTGTATGCCCGTTTCTGGAATCTGTTCCTTTATGACATCGGGGCGATCCCGAACAAAGAACCGTTCCAA
CGGCTATTTAATCAAGGGATGATTCTGGGCGATAATCATGAAAAGATGAGTAAGTCCAAGGGCAATGTGGTTAATCCAGA
TGATGTGGTTGATGAGTATGGTGCCGATACCTTGCGGCTGTACGAAATGTTTATGGGGCCGCTGGATGCTGGTATTGCTT
GGTCAACAAAGGGGTTAGCTGGTGCCCGCAAGTTCTTGGATCGCGTCTGGAGTGCTTTCATTGATGATGAAGGCAAACTG
CGTGATCGGATTACGACGATCAATGACGGTCGACTTGATAAGGTTTACAATGAGACGGTCAAGAAGGTTACCGAGGACTA
CGATGCTTTGCATTTCAACACGGCAATTTCACAGATGATGGTCTTCATCAACTCAGCGCGTAAAGATGATGACCTGCCAC
TAGAATATGTTGAAGGATTCGTGAAAATGCTTGCGCCGATTGCCCCGCATCTAATGGAAGAAATTTGGTCACGGCTAGGT
CACGATCATAGTCTGACTTATGCGCCATGGCCAAGTTATGATGAAAGCAAAATCAAAACCGACACTTACGATATGATGAT
CCAAGTCAATGGCAAGCTGCGCGGTTCGATTACGGCGGATGTCAACGAATCAGATGATGAGATCAAACAAGCGGCTTTGG
CAAATGATAATGTTCAGAAATTTACGGCGGGCAAAGACATTAAGAAAATTATTGTCGTACCGCGAAAAATCGTGAATATT
GTCGCAAAATAA

Protein sequence :
MAYDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVARMKRMQGFNVLHPMGWDA
FGLPAEQYALNTGHNPKTFTKQNIETFKRQINSLGFSYDWNREINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPD
LGTVVANEEVIDGKTERGGFPVVRKPMRQWMLKITAYAEKLLTDLDDLDWPESIKQMQRNWIGKSTGAQITFRVTDSHEP
FDVFTTRPDTLFGATYVVMAPEHELVQKITTPAQQAVVDAYIDEAAHKSDLDRTALDKEKTGVWTGAYATNPVNGEKLPI
WISDYVLASYGTGAIMSVPAHDDRDYAFAKKFGIEIKPVIEGGNVDEAAYTGDGVHINSGFLDGLNEHDAIDRMIKWLED
KGIGSAKINYKLRDWVFSRQRYWGEPIPVIHWEDGETTLVPEDELPLTLPEEADIKPSGTGESPLANLTDWVNVVDKNGR
KGKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKAWMPVDLYIGGAEHAVLHLLYARFWNLFLYDIGAIPNKEPFQ
RLFNQGMILGDNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTKGLAGARKFLDRVWSAFIDDEGKL
RDRITTINDGRLDKVYNETVKKVTEDYDALHFNTAISQMMVFINSARKDDDLPLEYVEGFVKMLAPIAPHLMEEIWSRLG
HDHSLTYAPWPSYDESKIKTDTYDMMIQVNGKLRGSITADVNESDDEIKQAALANDNVQKFTAGKDIKKIIVVPRKIVNI
VAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 65