Gene Information

Name : serS (LCABL_20590)
Accession : YP_001987984.1
Strain : Lactobacillus casei BL23
Genome accession: NC_010999
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1991871 - 1993154 bp
Length : 1284 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATCTAAAACTGATCCGGCAAAAACCGGAATGGGCCAAGGAAAAGTTAGCTGCACGTGCGATTAAAGGTGAAGA
GATTGATGAATTATTAGCTTTGGATACGCGCCGGCGTCAGGTGACCGTTCAAACTGAAGAGCTTAAAGCCAAGCGCAATG
ATGTTTCAGGCCAAATTGCGGTTATGAAACGTAACAAGGAAAATGCTGACGATCAAATCAAGGCCATGCGGGAAGTAGGC
CAAAAGATTGCGGCTTTAGACAAAGAACTCGCCCAGCTGAATGAAAAAGTAACCTACATTCTCGTCCGATTGCCAAACTT
TCCGGCTGATGACGTGCCAATGTCGTTAAATGAAGACGATTCCCGTGAAGAATACAAATGGGGAAACATGCCAACGTTTG
ATTTTGAACCAAAGCATCACTGGGATATTGGTGAAAAATTAGGCATTCTGGATTTTGAACGCGCGGCGAAGGTTGCCGGC
AGCAGATTTGTTTACTATAAGGGTGCTGGTGCACGTCTTGAACGCGCCGTCTATAACTTCTTCTTGGATGAGCACCAAAA
AGAAGGGTATGAAGAAATCATCCCCCCATACCTCGTTAACAATGATTCTATGTTCGGTACTGGTCAATTTCCAAAGTTTA
CTGATGCGACCTATACGATCACGAATGATGGTGAACCACTGACTCTGATTCCAACAGCAGAAGTGCCTTTGGTCAACTAT
TATCGGAATGACATTGTTGATGCTGAAAAACTTCCAGTTAATTTCACCGCACTTACACCGGCTTTTCGTTCTGAAGCTGG
CAGTGCCGGTCGCGATACTCGCGGCTTGATCCGGATGCATCAATTCAATAAGGTCGAAATGGTCAAGTTCTGCAAGCCTG
AAGATTCTTGGAAACAACTTCAAAACTTGATTCACGATGCCGAAGATCTTTTGCAAAAGCTCGGATTGCCTTATCATGTC
ATCACGCTGGCAAGTAATGACGCTAGCTTCACCAGTGCGAAGACGAATGATCTGGAAGTCTGGATGCCAGCGCAAGATCG
CTATCGTGAGATCTCAAGCTGCAGCAATTGCACTGATTTTCAGGCGCGTCGTGCACAAATTCGCTATCGTGATGACGACG
GCAAATTGCAGTTTGTCCACACGCTCAATGGCTCAGGGCTTGCTGTAGGGCGAACAGTGGCTTCTATTTTGGAAAATTAT
CAGCAAGCTGATGGTTCTGTGAAAATTCCCGATGTGCTTGTACCATACATGCAAGGACAAACTGCAATCACCAAAGAAGA
TTAA

Protein sequence :
MLDLKLIRQKPEWAKEKLAARAIKGEEIDELLALDTRRRQVTVQTEELKAKRNDVSGQIAVMKRNKENADDQIKAMREVG
QKIAALDKELAQLNEKVTYILVRLPNFPADDVPMSLNEDDSREEYKWGNMPTFDFEPKHHWDIGEKLGILDFERAAKVAG
SRFVYYKGAGARLERAVYNFFLDEHQKEGYEEIIPPYLVNNDSMFGTGQFPKFTDATYTITNDGEPLTLIPTAEVPLVNY
YRNDIVDAEKLPVNFTALTPAFRSEAGSAGRDTRGLIRMHQFNKVEMVKFCKPEDSWKQLQNLIHDAEDLLQKLGLPYHV
ITLASNDASFTSAKTNDLEVWMPAQDRYREISSCSNCTDFQARRAQIRYRDDDGKLQFVHTLNGSGLAVGRTVASILENY
QQADGSVKIPDVLVPYMQGQTAITKED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-129 61