Gene Information

Name : nrdF (LCABL_16930)
Accession : YP_001987632.1
Strain : Lactobacillus casei BL23
Genome accession: NC_010999
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 1632791 - 1633771 bp
Length : 981 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGGCAAAACAGTACATTGCGATCAATTGGAACGCGATCGAAGACGAAGTTGATAAAGCAACTTGGGAAAAATTGACGGA
ACAATTTTGGTTAGACACCCGGATTCCGCTGTCCAACGACTTGGACGACTGGCGATCTCTCAATCATGACGAGCAATGGG
TTGTCGGCCACGTGTTCGGTGGCTTGACCTTGTTAGATACCCTGCAGAGTCAGGACGGCATGGCAAGTTTGCGGCAGAAT
ATTCGCACCCAGCAAGAAACGGCTGTGTTGAACAACATTCAGTTTATGGAAAGTGTGCATGCAAAGAGTTACTCTTCGAT
TTTTTCAACGCTAAACACACCAGCGGAAATCGATGAGATCTTCGATTGGACCAATCATAATGAGCATCTGCAATACAAAG
CCAACAAAATTAATGATATTTATCATAACGGTTCAGCGTTGCAGAAAAAGATTGCCAGTGTTTTCTTGGAAACCTTCTTG
TTTTATTCAGGCTTCTTTACCCCGTTGTATTACTTGGGCAACAATAAGCTAACTAACGTGGCAGAAATCATTAAGCTGAT
TATTCGTGATGAAAGTGTTCATGGCACTTATATCGGCTATAAATTCCAGCTCGGATTCAACGAGTTACCGGAAGCTGAAC
AACAAACATTGAAGGATTGGATGTACGACTTGTTGTTCGATTTGTATGAAAACGAGGAAAAGTACACTAACGATCTTTAC
GCGAAGACCAACTGGACGGATGAAGTTTTGACTTTCTTGCGTTATAACGCCAACAAAGCCTTGATGAATTTAGGCCAGGA
AACGGCTTTTCCTGACACGGCCGATGACGTCAACCCAATCGTAATGAATGGGATTTCAACGTCTACCGCCAACCATGACT
TCTTCTCACAAGTTGGTAATGGTTACCGGCTGGGTCAAGTTGAAGCGATGCAAGATGATGATTATCAGTTCTCAACTGAA
GATGAAGACCACGACAAATAA

Protein sequence :
MAKQYIAINWNAIEDEVDKATWEKLTEQFWLDTRIPLSNDLDDWRSLNHDEQWVVGHVFGGLTLLDTLQSQDGMASLRQN
IRTQQETAVLNNIQFMESVHAKSYSSIFSTLNTPAEIDEIFDWTNHNEHLQYKANKINDIYHNGSALQKKIASVFLETFL
FYSGFFTPLYYLGNNKLTNVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQQTLKDWMYDLLFDLYENEEKYTNDLY
AKTNWTDEVLTFLRYNANKALMNLGQETAFPDTADDVNPIVMNGISTSTANHDFFSQVGNGYRLGQVEAMQDDDYQFSTE
DEDHDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 5e-70 48