Gene Information

Name : panE (LCABL_16650)
Accession : YP_001987604.1
Strain : Lactobacillus casei BL23
Genome accession: NC_010999
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 1601674 - 1602618 bp
Length : 945 bp
Strand : -
Note : Ketopantoate reductase; catalyzes the NADPH reduction of Ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAAAATTACAATTGCTGGTGTCGGGGCCATGGGTGGCCGCTATGCATTGATGCTCAGTCGAGCAGGCAACGATGTCGA
CGGTATTGACGGCTGGGCTGACAATGTGAATGCCATCAATGAGCATGGCCTGCAGGCTAACTTCGATGGCGAACAAGTTG
TTGCTAAGATCAAAGCCTATGAACAAACCAAAATTGATCCAAGTGCAGTGGCTGATCTCGTCATCCTCTTCCCGAAATCC
ATGCAACTAGACGGTATGATGCAGTCATTAAAGCCGGTGATCACTGACCATACTAAAATTCTGTGTTTAATGAATGGTAT
CGGTCATGAAGAAATCATCGAAAAATATGTCACACGCGACAATATTTTTATTGGTAATACGATGTGGACCGCCGGAATGG
AAGGACCAGGCAAATTAAAGCTATTCGGCAGCGGTTCAGTCGCCTTGCGCAACGTCGAAGACGGCGAAGCAGCAACCGCA
GCTGCAAAAAAGATCGTGAAATTGTTATCAGACGCTGGACTAAATGCTGAATACTCTGATAATATTCTGTATACGATCTA
CAAGAAAGCAACGGTCAATGGCACAATGAACGGCTTATGCACGATTCTGGACTGCAATATGAGTGAATTTGGCAGCACCT
CAACCGCTGAGGACATGGTTGTCGCAATCGTCAAAGAATTCTCGGCAGTTGCCGCAAAAGAAGGCATTGATTTGAATGTG
CCTGACACGGTGGACTACATCAAAACAACCTGGGATCCAAACACGATCGGCCATCATTACCCGTCCATGCATCAAGACCT
GATTACCAATCACCGCTTGACTGAGATCGATTATATTAACGGTGTGATTGATCGGCGCGGTAAGAAGTACGGTATTCCGA
CCCCATACTGTACCTTCTTAACCCAACTAGTCCACGCCAAGGAACAGTTGCTGCACGCAAAATAA

Protein sequence :
MKITIAGVGAMGGRYALMLSRAGNDVDGIDGWADNVNAINEHGLQANFDGEQVVAKIKAYEQTKIDPSAVADLVILFPKS
MQLDGMMQSLKPVITDHTKILCLMNGIGHEEIIEKYVTRDNIFIGNTMWTAGMEGPGKLKLFGSGSVALRNVEDGEAATA
AAKKIVKLLSDAGLNAEYSDNILYTIYKKATVNGTMNGLCTILDCNMSEFGSTSTAEDMVVAIVKEFSAVAAKEGIDLNV
PDTVDYIKTTWDPNTIGHHYPSMHQDLITNHRLTEIDYINGVIDRRGKKYGIPTPYCTFLTQLVHAKEQLLHAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 7e-101 62
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 5e-101 62