Gene Information

Name : pyk (LCABL_15850)
Accession : YP_001987524.1
Strain : Lactobacillus casei BL23
Genome accession: NC_010999
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1520889 - 1522655 bp
Length : 1767 bp
Strand : +
Note : -

DNA sequence :
ATGAAAAAAACCAAGATCGTCAGCACGCTTGGACCTGCAAGTAACACCACTGATATCATCGTTAAGTTGATTGAAGCGGG
TGCCAACGTTTTCCGTTTCAATTTCTCACATGGTGATCATGAAGAGCATTTGGCACGGATGAACATGGTTCACGAAGCTG
AAAAGATCACGGGTAAGACCGTTGGTATCATGCTGGATACGAAGGGTGCCGAAATTCGGACAACTCTTGAAGATACCCCG
AATGGTAAGATCGATTTTCACACCGGTGACAAAGTTCGCATCTCCATGGATGCAAGTCTGAAAGGCACCAAGGAAAAAGT
TGCTGTTACCTATCCTGGCCTTTATGATGACACTCACGTTGGCGGCCATGTTTTGTTTGATGATGGCTTGATTGACATGA
AGATCACCGAAAAGGACGAAAAGAACCGTGAACTCGTTACCGTTGTTCAAAACGACGGTGTCCTTGGTGGTAAGAAAGGT
GTCAACGCTCCTGGTGTTGCCATCAACTTGCCTGGGATTACGGAAAAAGACTCCGATGACATTCGTTTCGGCTTGGACAA
CGGGATCAACTTCATTGCTGCTTCCTTTGTTCGTAAGCCTCAAGACGTTTTAGACATTCGTGAACTCCTTGAAGAAAAGA
ACGCACTTAATGTTCAGATCTTCCCTAAGATCGAATCACAAGAAGGCATCGACAACATTGATGACATCTTGAAGGTTTCC
GATGGCTTAATGGTTGCTCGTGGCGACATGGGTGTTGAAATTCCATTTGAACATGTTCCGATCGTTCAGAAGCGCTTGAT
CAAGAAGTGCAACTCTTTGGGTAAGCCGGTTATCACGGCTACACAAATGTTGGATTCCATGCAAGAAAACCCACGTCCTA
CCCGTGCCGAAGTAAACGACGTTGCCAATGCCGTGTTTGATGGCACCGATGCAACGATGCTTTCTGGCGAATCTGCTAAT
GGTGACTATCCGGTTGAATCCGTTGCTGCAATGGCTCGGATTGACGAATACACCGAAGCAGCGATGATGGATCAGGATGC
CTTCGCATTGAAGGAATACAGTAACAAGAACGTCACCGAAGCTGTTGGCCAAAGTGTTGCACACACGGCTCGCAACTTAG
GGGTTAAGACCATTGTTGCTGCGACCGAATCCGGCTACACTGCCCGCATGATTTCCAAGTATCGTCCGAAGGCTGACATT
CTTGCCATTACCTTCAGCGAAAAGACCCAACGCGGCCTGATGGTCAACTGGGGTGTTTACCCAATCATTGCTGAAAAGCC
TGCTAACACCGATGCTATGTTCGACTTGGCAACCAAGAAGGCCCAAGACCTTGGCTTTGCTAAGGAAGGCGATCTGATCT
TGATCACTGCCGGTGTTCCTGTTGGTGAATCTGGCACAACCAACGTAATGAAGGTTCAACTCATTGGCTCCAAGCTGGTT
CAAGGCTCAGGTGTCGGCGACGAATCCACGATTGGTAAGGCAGTCATCGCAAGCAACGCTCAAGAAGCTGCTGCTAAGAT
GCAAAAGGGTGACATTCTGGTTGTTAAGACGACTGACAAAGATTACTTGCCAGCAATCGAAAAAGCAGCTGCCTTGGTTG
TTGAAACCGGTGGCTTGACCAGTCACGCAGCTGTTGTTGGTATTGCTATGGGTATCCCAGTTGTTGTTGGTGCTGAAAAT
GCTACCAGCGTCATCTCCGATGGCCAGATCATTACTGTTGACTCCCGTCGTGGGATCATCTACAAAGGTGCTACCAACGC
CCTTTAA

Protein sequence :
MKKTKIVSTLGPASNTTDIIVKLIEAGANVFRFNFSHGDHEEHLARMNMVHEAEKITGKTVGIMLDTKGAEIRTTLEDTP
NGKIDFHTGDKVRISMDASLKGTKEKVAVTYPGLYDDTHVGGHVLFDDGLIDMKITEKDEKNRELVTVVQNDGVLGGKKG
VNAPGVAINLPGITEKDSDDIRFGLDNGINFIAASFVRKPQDVLDIRELLEEKNALNVQIFPKIESQEGIDNIDDILKVS
DGLMVARGDMGVEIPFEHVPIVQKRLIKKCNSLGKPVITATQMLDSMQENPRPTRAEVNDVANAVFDGTDATMLSGESAN
GDYPVESVAAMARIDEYTEAAMMDQDAFALKEYSNKNVTEAVGQSVAHTARNLGVKTIVAATESGYTARMISKYRPKADI
LAITFSEKTQRGLMVNWGVYPIIAEKPANTDAMFDLATKKAQDLGFAKEGDLILITAGVPVGESGTTNVMKVQLIGSKLV
QGSGVGDESTIGKAVIASNAQEAAAKMQKGDILVVKTTDKDYLPAIEKAAALVVETGGLTSHAAVVGIAMGIPVVVGAEN
ATSVISDGQIITVDSRRGIIYKGATNAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-90 48
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-91 48
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-91 48
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-90 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_001987524.1 pyruvate kinase VFG0479 Protein 3e-91 48