Gene Information

Name : pdhD (LCABL_15390)
Accession : YP_001987478.1
Strain : Lactobacillus casei BL23
Genome accession: NC_010999
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 1465519 - 1466922 bp
Length : 1404 bp
Strand : +
Note : E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGGTTGTAGGCGATTTTGCAATCGATTTGGATACCGTCGTCATTGGTTCCGGCCCCGGCGGTTATGTTGCTGCGATTCG
CGCAGCTGAAATGGGTCAAAAGGTGACCGTGATTGAGAGCACGTTCATTGGCGGTGTTTGTTTGAATGTCGGCTGCATCC
CATCAAAAGCTTTGATCAACGCAGGTCATCGCTATCAAGACGCCTTGGAAGCAAGTACGTTTGGCATTCATGCCAAAGGT
GCTGACCTTGATTTCACGAAAACCCAGGAATGGAAGCAAAATAAGGTTGTGCATACGCTGACAAGCGGTGTGTCGATGCT
ATTCAAGAAACACAAGATTGACACGATTATGGGCACGGCGTTCTTAAAAGATGACCATAGCCTGCGCGTGATGCAAAAAG
ATTCAGCTCAGACCTATACGTTCAAGAATCTGATCATCGCGACTGGCAGCCGGCCAATCGAAATTAAAGGCTTTAAGTTT
GGCAAGCGCATTTTAGATTCAACAGGGGGTCTGAATCTTCCTGAAGTACCAAAAGAATTTGTCGTCATTGGCGGCGGCTA
TATCGGCTCCGAGTTGGCGAGTGCGTATGCTAATCTTGGCGCGCATGTCACGATTCTTGAAGGCACAAGTTCGATTCTGC
CAAACTTTGAGAAGGATATGGTTCAGCTAGTTCTGAATTCCTTCAAAAAACGTGGCGTAACAGTTATTACCAATGCGATG
GCTAAAGAAGCTGAAGACACTGGCAAAGGTGTCAAAGTGACGTACACGGCCGATGGTAAGGAACAGACGATTGCCGCTGA
TTATGTTATGGTGACGGTTGGACGGCGGCCAAATACTGACGATCTTGGTCTCGATATTGTCGGGGTCGAAACAACTGATC
GCGGTTTAATCAAGGTCGATGCTCAAGGCCGGACCAACAAACCGAATATCTATGCGATTGGCGACATTGTGCCAGGTGCA
GCATTGGCGCATAAGGCTAGCTATGAAGGTAAAGTCGCTGCCGAGGCCATCAGCGGCAAAGCCAGTGCGGTTGACTACAA
AGCGATGCCTGCCGTTTGCTTCACGGACCCTGAACTTGCAACAACTGGGATGACAGTTGCCGAGGCGAAGGATAAAGGGA
TCAAGGCTAAAGCCAGCAAGTTCCCATTTGCTGCCAATGGTCGTGCCCTCAGTCTTGCCCAGACAGAAGGGTTTGTCCGC
TTGGTCACTAATGAAAACGGTACGGTTATCGGCGGCCAAGTTGCTGGCGCCGGTGCTAGTGATTTGATTTCCGAACTGAC
CGTTGCTGTTGAAGGCGGTTTGAACGTTGAGGATCTTGCCTTGACCATTCATCCGCACCCAACACTGAGTGAAGTTATCA
TGGATGACGCTGAAGTTGCATTGGGACTCCCAATCAATATTTAG

Protein sequence :
MVVGDFAIDLDTVVIGSGPGGYVAAIRAAEMGQKVTVIESTFIGGVCLNVGCIPSKALINAGHRYQDALEASTFGIHAKG
ADLDFTKTQEWKQNKVVHTLTSGVSMLFKKHKIDTIMGTAFLKDDHSLRVMQKDSAQTYTFKNLIIATGSRPIEIKGFKF
GKRILDSTGGLNLPEVPKEFVVIGGGYIGSELASAYANLGAHVTILEGTSSILPNFEKDMVQLVLNSFKKRGVTVITNAM
AKEAEDTGKGVKVTYTADGKEQTIAADYVMVTVGRRPNTDDLGLDIVGVETTDRGLIKVDAQGRTNKPNIYAIGDIVPGA
ALAHKASYEGKVAAEAISGKASAVDYKAMPAVCFTDPELATTGMTVAEAKDKGIKAKASKFPFAANGRALSLAQTEGFVR
LVTNENGTVIGGQVAGAGASDLISELTVAVEGGLNVEDLALTIHPHPTLSEVIMDDAEVALGLPINI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 3e-102 48