Gene Information

Name : secA (LCABL_10420)
Accession : YP_001986986.1
Strain : Lactobacillus casei BL23
Genome accession: NC_010999
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1003377 - 1005740 bp
Length : 2364 bp
Strand : +
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCCAATATTCTTAGAAAATGGGTCGAAAGCGATAAGCGAGAAATCGCGCGCCTAGGCAAAATTGCTGATAAGGTTCA
GCAATATGAAGATGAGTATGCAGCATTATCTGATGAACAATTAAAAGCAAACACACCAAAATTAAAAGATCGTCTCGCAG
CTGGTGCTACCCTTGATGACATTCTGCCAGAAGCCTTTGCGACTGCGCGGGAAGGTGCCAAGCGTGTTTTAGGTCTATTC
CCGTTCCGAGTCCAAATTATTGGCGGGATTGTGTTGCATGAAGGCAACATTGCGGAGATGAAGACCGGTGAAGGGAAAAC
TTTAACCGCAACCATGCCTGTTTATTTGAACGCACTCACTGGTAAAGGTGTTCATGTTGTCACGGTCAATGAGTACCTGT
CAACCCGTGATGCCACGGAAATGGGCGAGCTATACAACTGGCTTGGCTTGAGCGTAGGGTTAAACCTCAATTCCAAGAAC
AGTGATGAAAAACGAGAAGCTTATAATTGCGACATTACCTATTCCACGAACAGTGAACTCGGGTTTGACTATCTGCGTGA
CAACATGGTTGTTTACAAAGAGCAGATGGTTCAGCGGCCACTGAATTTTGCAATCGTCGATGAAGTTGACTCTATTTTGA
TTGATGAGGCGCGAACCCCATTGATCATTTCTGGCGGCGCCGAAAAAACAACCGGTCTCTACATTCGTGCCGATCGGTTT
GTCAAGACGCTAAAAGCGGAGACCGATTACAAGATCGACTGGCCAACGAAGACAATCTCGTTAACTGAAAGCGGCATCCG
GAAGGCTGAAAAGAATTTCGGACTGGATAATCTGTATGACACCGAAAATACGGCCTTAACGCATCATATTGATCAGGCCT
TGCGGGCTAATTACATCATGCTCAAGGATATCGATTACATGGTTTCCGATGGTGAAGTCCTCATTGTTGATCAGTTTACT
GGCCGAGCAATGGAAGGTCGCCGATATTCTGACGGCTTGCATCAGGCGATTGAAGCCAAAGAAGGCGTCCAAATTCAGGA
CGAAAATAAGACGATGGCTAACATCACTTATCAAAACTTCTTCCGGATGTACACAAAGTTGGCCGGGATGACTGGGACCG
CAAAGACCGAGCAAGAAGAATTCCGAGAAATTTATAACATGGAAGTCATCTCTGTTCCGACCAACAAGCCAGTTATCCGG
GTTGACTCCCCTGACGTGCTGTACCCGACGTTAGATGCTAAGTTCAACGCGGTTGTTGAAGACATCAAAGCGCGTCATGA
AAAAGGCCAGCCGATGCTGATTGGGACGGTTGCGATTGAATCGAGTGAACGGCTTAGTAAGCAACTTGATGAAGCTAAGA
TTCCACATACCGTTTTGAACGCGAAGAATCACTTTAAAGAAGCAGAAATCATTATGAATGCTGGCCAACGCGGCGCTGTG
ACGATTGCGACGAACATGGCTGGGCGTGGTACGGATATCAAACTTGGACCTGGTGTCACCGAACTTGGCGGTTTGGCAGT
TATCGGGACGGAACGCCATGAAAGTCGTCGAATTGATAATCAGTTGCGAGGCCGTTCAGGGCGTCAAGGCGATCCAGGTT
CTACACAGTTTTACCTGAGCCTTGAAGATGATCTGATGAAACGCTTTGGTTCTGATCGAATTAAAGCTATGTTGGATCGC
TTTAAGGTGGCGGATGATGATCAGGTGATTCAAAGTCGGATGATTTCACGGCAGGTGGAGTCAGCCCAGAAACGGGTCGA
AGGGAATAACTACGACACGCGGAAGAATACGCTGCAATATGATGATGTGATGCGTGAACAACGCGAGGTCATTTACAAGC
AGCGGCAGCAAGTCATCAATGAACAGGAAACGTTGAAGCCTGTCTTGATGGCTATGATCAATCGAACAATTACACGGATT
GTTCAGACTCATACCCAAGGAGATCAGAAGGACTGGAACCTTGATGCCTTGTACGCTTGGGTCACTGCCAACATGATTGA
TCCTGAGAAATTCAAACGCAGCCAGTTAGATGGCAAGTCGCAAGACGAGTTGATCGGGTTACTGGCCGAGATGGCGGAGA
CCAACTTCCAGCAAAAGAATAAGCAGCTAGGCGATGACGCGCAGATGCTTGAATTCGAAAAAGTTGTTATTTTGCGCGTG
GTTGATTCTGCTTGGACCGATCATATTGATGCGATGGATCAGTTGCGGCAGTCGATCGGATTGCGCGGTTATGGTCAAAT
GAATCCGCTAGTCGAATATCAAGAAGAAGGCTACCGGATGTTTGAAGAAATGATTGCATCAATTGATGATGATGTGACTC
GGCTGTTCATGAAAGCTGAAATCCGACAAAATATTCGCCGTTAA

Protein sequence :
MANILRKWVESDKREIARLGKIADKVQQYEDEYAALSDEQLKANTPKLKDRLAAGATLDDILPEAFATAREGAKRVLGLF
PFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNSKN
SDEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYIRADRF
VKTLKAETDYKIDWPTKTISLTESGIRKAEKNFGLDNLYDTENTALTHHIDQALRANYIMLKDIDYMVSDGEVLIVDQFT
GRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAKTEQEEFREIYNMEVISVPTNKPVIR
VDSPDVLYPTLDAKFNAVVEDIKARHEKGQPMLIGTVAIESSERLSKQLDEAKIPHTVLNAKNHFKEAEIIMNAGQRGAV
TIATNMAGRGTDIKLGPGVTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKRFGSDRIKAMLDR
FKVADDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQVINEQETLKPVLMAMINRTITRI
VQTHTQGDQKDWNLDALYAWVTANMIDPEKFKRSQLDGKSQDELIGLLAEMAETNFQQKNKQLGDDAQMLEFEKVVILRV
VDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEIRQNIRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-148 43