Gene Information

Name : hrcN (RHECIAT_PB0000089)
Accession : YP_001984352.1
Strain :
Genome accession: NC_010996
Putative virulence/resistance : Virulence
Product : type III secretion system ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 100293 - 101612 bp
Length : 1320 bp
Strand : +
Note : -

DNA sequence :
ATGGTTGACGCGTTGCTTCGGATGGAGCGGACGCTCGAACAAACGGACGTGCGGCGGCAGAGCGGCCGCGTGACGAGTGT
TTCGGGCCTGCTGGTGCGGGCGCTCATCCCCTCGGTCAGGATCGGCGAGCTCTGCGAACTGCATGAGCCGGGCAGGGGCC
GCATCGGCCTCGCCGATGTCGTCGGTATCGACGGCGAGACGGCACTTCTCTCGCTTCACGGCGAAACCCGCGGCATCTCC
CAGCGCACGGAAATCGTCCCGACCGGCCGGGAGCCGGCGATCTCTGTCGGCAACTTCCTGCTCGGCGCGATCGTCGATGC
GCACGGCAACGTCCTGCGTCCCTCCGCCAATCCGGCCGGCGAGGACGCGCGTTTCCTGCAGCCGCTCTACGGCCAGCCGG
TCAACCCCTTGTCGCGCCGTCCCATCCGCCAGCCGTTCACCTCGGGAATTGCCGCCCTGGACGGATTGCTGACCTGCGGC
CAGGGCCAGCGCATCGGTATTTTCGGCGCGCCTGGCGCCGGCAAGTCGACGCTGGTGTCCCAGATCGTCGCCAACAACAA
GGCCGATGTGATCGTCTGCGCCCTGGTGGGCGAACGCGGACGCGAGGTCGGCGAATTCGTTGCCGGCAACATGCCGGAAG
GCGTCCCCTCGAATGTGACGCTGGTTGTCGCCACATCCGACCGCCCGGCGCTGGAGCGGTTCAAGGCGGTGATGACGGCA
ACGGCGATCGCCGAATATTTTCGCGAGCAGGGAAAACACGTGCTGCTCGTCATCGACAGCGTCACCCGCATGGCCCGCGC
CTTGCGCGAAGTGGGGCTTGCCGCCGGCGAACCGCCGGTGCGGCGCGGCTTTCCGCCTTCCGTATTCGCCGTCCTGCCGC
AAATCTTCGAGCGTGCCGGCAACAGCGCAAACGGCATGATGACGGCTTTCTATACGGTGCTCGTCGAAGGCGAAGAGCAA
GACGATCCGATTGCCGAAGAAACCAGATCGCTGCTGGACGGCCATATCGTGCTCTCCGACAAGATTGCCAAGGCAGGCAA
TTTTCCGGCGATCGATGTGCTGGCCAGCCGAAGCCGGACGATGAGCGCAGTGGTGAGCGAGAGCCATCGCCAGGCAGCCG
ACAGGCTGCGCGCCCTGCTTGCCCTCTATGACGAGGTGGAACTGCTGATCCGCGTCGGCGAATATCGCCAGGGGCGCGAT
GCCGCCGTCGACGAGGCCGTCGCCAAACACGGGCTCATCCAGCGCTTCCTGTTTGACGGCCAGGGCAAGCCGCAGCCGTT
CGGCGCGATCGTCGAAGCGCTCGAGGAGCTTGTCCGATGA

Protein sequence :
MVDALLRMERTLEQTDVRRQSGRVTSVSGLLVRALIPSVRIGELCELHEPGRGRIGLADVVGIDGETALLSLHGETRGIS
QRTEIVPTGREPAISVGNFLLGAIVDAHGNVLRPSANPAGEDARFLQPLYGQPVNPLSRRPIRQPFTSGIAALDGLLTCG
QGQRIGIFGAPGAGKSTLVSQIVANNKADVIVCALVGERGREVGEFVAGNMPEGVPSNVTLVVATSDRPALERFKAVMTA
TAIAEYFREQGKHVLLVIDSVTRMARALREVGLAAGEPPVRRGFPPSVFAVLPQIFERAGNSANGMMTAFYTVLVEGEEQ
DDPIAEETRSLLDGHIVLSDKIAKAGNFPAIDVLASRSRTMSAVVSESHRQAADRLRALLALYDEVELLIRVGEYRQGRD
AAVDEAVAKHGLIQRFLFDGQGKPQPFGAIVEALEELVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-98 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-80 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-80 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-79 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-79 48
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-78 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-78 48
escN AAC31513.1 L0034 Virulence LEE Protein 1e-83 48
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-83 48
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-82 48
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-83 48
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-83 48
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-84 48
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-78 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-78 48
unnamed AAL06369.1 EscN Virulence LEE Protein 7e-81 48
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 8e-79 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-78 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 8e-79 47
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-78 47
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 6e-79 47
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-77 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-77 47
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-77 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-77 47
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-77 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-82 47
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-82 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-82 47
escN AAK26715.1 EscN Virulence LEE Protein 1e-82 47
escN AAL57542.1 EscN Virulence LEE Protein 1e-82 47
escN AAC38383.1 EscN Virulence LEE Protein 2e-83 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-66 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-65 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 7e-68 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-69 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 6e-69 45
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-75 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-62 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-62 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 7e-71 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-71 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-71 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-75 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-72 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-72 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-72 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-72 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-71 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-72 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hrcN YP_001984352.1 type III secretion system ATP synthase VFG0192 Protein 2e-98 52
hrcN YP_001984352.1 type III secretion system ATP synthase VFG0390 Protein 2e-95 51
hrcN YP_001984352.1 type III secretion system ATP synthase VFG0048 Protein 2e-94 49
hrcN YP_001984352.1 type III secretion system ATP synthase VFG0812 Protein 6e-84 48
hrcN YP_001984352.1 type III secretion system ATP synthase VFG0515 Protein 1e-77 47
hrcN YP_001984352.1 type III secretion system ATP synthase VFG0730 Protein 1e-83 47
hrcN YP_001984352.1 type III secretion system ATP synthase VFG2459 Protein 1e-73 45
hrcN YP_001984352.1 type III secretion system ATP synthase VFG2144 Protein 1e-81 44
hrcN YP_001984352.1 type III secretion system ATP synthase VFG1008 Protein 7e-67 44
hrcN YP_001984352.1 type III secretion system ATP synthase VFG1778 Protein 2e-73 44
hrcN YP_001984352.1 type III secretion system ATP synthase VFG0555 Protein 8e-73 42
hrcN YP_001984352.1 type III secretion system ATP synthase VFG1254 Protein 4e-65 41
hrcN YP_001984352.1 type III secretion system ATP synthase VFG2499 Protein 2e-67 41