Gene Information

Name : guaA (CJA_2103)
Accession : YP_001982568.1
Strain : Cellvibrio japonicus Ueda107
Genome accession: NC_010995
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2430677 - 2432254 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACTCACGATATACACGCCCAGCGAATTCTGATCCTGGATTTCGGCTCGCAATACACTCAACTGATTGCGCGCCGCGT
ACGCGAAATCGGTGTTTTCTCGGAAATTCGCGCCTGGGATATGAGCGACGATGAAATCCGTGCTTATAAGCCCAGTGGGA
TTATCCTCGCCGGCGGTCCTGAATCTACCACGGAAGAGGAGGCACCCCGAGCACCTGAAGCGGTATTTGCACTGGGAGTT
CCTGTCCTGGGTATTTGCTACGGTATGCAAACCATGGCGATGCAAATGGGGGGCTGGGTAGAGTCTTCCGCTATTCGTGA
ATTCGGCTATGCACAGATCAAGGCTCATGGTCAGTCCTCATTGTTGCAGGATATTAAAGATCATGTGGATCAGGATGGCT
CTGCGTTACTGGATGTGTGGATGAGCCATGGTGATAAAGTCACCAAAATGCCGGAAGGTTTTGAACTGATGGCGTCTACG
CCCTCCTGCCCCATTGCCGGCATGTATAACGAGGCGAAAAAATTCTACGGTGTGCAGTTCCATCCGGAAGTAACCCATAC
CTTGCAAGGCAAGCGTTTGTTTGAGCACTTTGTATTGCAACTCTGTGCCTGCGAAAAGCTCTGGACCCCTGCCAATATTG
TAGAAGACGCTATCAAAAAGGTGCGCGAACAAGTCGGTACCGATAAAGTGCTGCTGGGCCTTTCCGGTGGGGTAGACTCT
TCTGTAGTGGCAGCGTTGTTACACCGTGCTATTGGCGACCAGCTCACCTGTGTGTTTGTGGATAACGGATTGCTGCGCAA
AAATGAAGGCGATCAGGTGATGGACATGTTTGCCAAAAACATGGGTGTGCGCGTGATTCGTGCGGATGCGGAACAGCTGT
TCCTGGGCAAGCTTGCTGGTGTGAGTGACCCGGAGAAAAAACGCAAAATCATTGGCGGTACCTTTATCGATGTATTTGAT
ACTGAAGCGACCAAATTACAAGAAGTGAAGTGGTTGGCCCAAGGTACCATTTACCCGGATGTGATCGAGTCCGCCGCCGC
CAAAACCGGCAAAGCCCATGTGATTAAATCCCACCATAATGTCGGTGGTTTGCCGGAAGACATGGCCTTTAAATTGGTGG
AGCCCCTGCGTGAACTTTTTAAAGATGAGGTCCGCGCTATTGGCTTGGAGTTGGGCCTGCCCTATGACATGGTGTACCGC
CATCCATTCCCGGGCCCGGGTTTGGGGGTACGTATTCTTGGCGAAGTGAAAAAAGAATATGCCGATATTCTGCGCGAAGC
TGATGCTATTTTTCTGGAGGAGTTGCGCGCAGCCGATTGGTACCACAAAACTTCCCAGGCATTTGCTGTCTTCCTGCCGG
TCAAGTCGGTTGGTGTTGTCGGTGATGGTCGCCGTTATGAATGGGTCATATCACTGCGCGCGGTAGAGACGGTCGACTTT
ATGACAGCGCGCTGGGCTCACCTGCCTTACGAACTGTTGGAAAAAGTGTCCAATCGGATTATCAATGAAATTTCCGGTGT
GTCGCGTGTGTGCTATGACGTATCGAGCAAACCGCCCGCTACCATTGAATGGGAATAA

Protein sequence :
MTHDIHAQRILILDFGSQYTQLIARRVREIGVFSEIRAWDMSDDEIRAYKPSGIILAGGPESTTEEEAPRAPEAVFALGV
PVLGICYGMQTMAMQMGGWVESSAIREFGYAQIKAHGQSSLLQDIKDHVDQDGSALLDVWMSHGDKVTKMPEGFELMAST
PSCPIAGMYNEAKKFYGVQFHPEVTHTLQGKRLFEHFVLQLCACEKLWTPANIVEDAIKKVREQVGTDKVLLGLSGGVDS
SVVAALLHRAIGDQLTCVFVDNGLLRKNEGDQVMDMFAKNMGVRVIRADAEQLFLGKLAGVSDPEKKRKIIGGTFIDVFD
TEATKLQEVKWLAQGTIYPDVIESAAAKTGKAHVIKSHHNVGGLPEDMAFKLVEPLRELFKDEVRAIGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADILREADAIFLEELRAADWYHKTSQAFAVFLPVKSVGVVGDGRRYEWVISLRAVETVDF
MTARWAHLPYELLEKVSNRIINEISGVSRVCYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-125 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-125 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-125 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-112 49