Gene Information

Name : guaA (RHECIAT_CH0000334)
Accession : YP_001976506.1
Strain : Rhizobium etli CIAT 652
Genome accession: NC_010994
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 340619 - 342181 bp
Length : 1563 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCACACAGCACATCCCGACTCCGTTCTCATCGTCGATTTCGGCAGCCAGGTGACCCAGCTCATCGCACGACGCGT
GCGCGAGGCCGGCGTCTATTGCGAAATCGTTCCCTTCCAATCGGCCGAAGAGGGCTTCAAGCGCCTGCAGCCGAAAGCCG
TGATCCTGTCCGGCAGCCCGGCTTCGACGGTCGACGAGGGATCGCCGCGAGCGCCGCAGATCATCTTCGACAGCGGTCTG
CCGGTCTTCGGCATCTGTTATGGCCAGCAGACGATGTGCATGCAGCTCGGCGGCAAGGTCGAAAGCGGCCATCACCGCGA
ATTCGGCCGCGCCTTCCTCGACGTCGATAAGGATTGCCAGCTGTTCGAAGGTCTCTGGTCCTCCGGCTCGCGCCATCAGG
TGTGGATGAGCCATGGCGACCGCGTCACGGCGCTGCCCGATGGTTTCGAGGTGGTCGCCACCTCCTCCAACGCGCCCTTC
GCCTTCATCGCCGACGAGAAGCGTAAATATTACGGCGTGCAGTTCCATCCCGAGGTCGTGCATACGCCCGACGGGGCAAA
GCTGATCGGCAATTTCATTCACAATATTGCCGGCATCAAGGGCGACTGGTCGATGTCGGCCTACCGCCAGAAGGCGGTCG
ACGAGATCCGCAAGCAGGTGGGCGACAAGCGCGTCATCTGTGCGCTTTCCGGCGGCGTTGACAGTTCGGTCGCCGCGCTC
TTGATCCACGAGGCGGTCGGCGATCAGCTGACCTGCATCCTCGTTGACCACGGCCTGATGCGCAAGGACGAGGCAGCAAA
CGTCGTCGCCATGTTCCGTGAGCACTACAATCTGCATCTGCTGCACGTCGACGCCTCGGACCGTTTCATCGGCGAGCTCG
AAGGCGTCAGCGACCCGGAAACCAAACGCAAGATCATCGGCCGGCTGTTCATCGAGACTTTCGAGGAAGAGGCAAAGAAA
CTCGGCGGCGCCGATTTCCTCGGCCAGGGCACGCTCTATCCCGACGTGATCGAGAGCGTTTCCTTCACCGGCGGTCCGTC
GGTGACAATCAAGTCGCATCACAATGTCGGCGGCCTGCCGGAGCGCATGAAGATGCAGCTCGTCGAGCCGCTGCGCGAGC
TCTTCAAGGACGAGGTGCGCGCGCTCGGCCGCGAGCTCGGCCTGCCCGACAGCTTCATCGGCCGCCACCCCTTCCCCGGC
CCCGGCCTTGCCATCCGCTGCCCCGGCGGCATCAGCCGCGAAAAGCTGGAGATCCTGCGCGAGGCCGACGCGATCTATCT
CGACGAGATCCGCAAGGCCGGCCTCTACGATGCCATCTGGCAGGCCTTCGCCGTGCTGCTGCCCGTCCAGACCGTCGGCG
TCATGGGCGACGGGCGCACATACGAGTTCGTCTGCGCGCTGCGCGCCGTCACCTCCGTCGACGGCATGACCGCGGATTTC
TACCACTACGACATGGAATTCCTCGGTCGCGCCGCAACGCGCATCATCAACGAAGTGCGCGGCATCAACCGCGTGGTCTA
TGACGTCACATCGAAGCCGCCCGGCACGATCGAGTGGGAGTGA

Protein sequence :
MTHTAHPDSVLIVDFGSQVTQLIARRVREAGVYCEIVPFQSAEEGFKRLQPKAVILSGSPASTVDEGSPRAPQIIFDSGL
PVFGICYGQQTMCMQLGGKVESGHHREFGRAFLDVDKDCQLFEGLWSSGSRHQVWMSHGDRVTALPDGFEVVATSSNAPF
AFIADEKRKYYGVQFHPEVVHTPDGAKLIGNFIHNIAGIKGDWSMSAYRQKAVDEIRKQVGDKRVICALSGGVDSSVAAL
LIHEAVGDQLTCILVDHGLMRKDEAANVVAMFREHYNLHLLHVDASDRFIGELEGVSDPETKRKIIGRLFIETFEEEAKK
LGGADFLGQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRALGRELGLPDSFIGRHPFPG
PGLAIRCPGGISREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADF
YHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-137 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-137 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-137 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-116 50