Gene Information

Name : hemC (WPa_0474)
Accession : YP_001975253.1
Strain : Wolbachia endosymbiont wPip
Genome accession: NC_010981
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 510804 - 511682 bp
Length : 879 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCTAGTTAAAATAGGTACGAGAGGAAGCGACCTTGCGCTCATCCAAGCTTTGGAAGCAAAACAAAGATTATTAGAGTC
TTTTCCTAATCTATCCGTTGAGATCATTAAAATCAAAACTTCTGGTGATAAATATGCTAATGTAACCCTTGCTGAAATAG
GAGGTAAAGGACTGTTCCTCAGGGAGATTGAGGCTGAATTACTCAAAAATAATATAGATATGGCGGTTCATTCGCTAAAA
GATGTACCTGCGTTTTTCTCGAAGGACTTAACAATTCCTTGTGTTTTAGAGAGGCTAAGTCCATGTGATGTATTTATTTC
TCATAAATATAAGAGCCTAAAAACTTTGCCACAGCAGGCTACAATTGCAACTTCTTCAATAAGAAGAAAAGTTCAGCTGT
TAAATCTCAGGCCAGACTTAAATGTAGTGCCACTGCGTGGAAATGTGACAACTAGACTGCAAAATCAGAATTTTGATGGA
ATGATTTTAGCTGAAGCAGGGCTGATAAGATTAAAAAAATATCACTTAATTACAGAGGTATTGCCACCAAAAGTCATGTT
AAGCGCAGTAGGGCAGGGGACAATTTGCATTCAATGCCGAAAGAATGATATAAAAGTTATCGATCTTTTAGAGAAAATTA
ATAATAATATGTCTTTTATAAGGGCAAAATCAGAGCGCAGTTTCATGAAGACAGTAAATGGTTCATGCTTTACACCGCTT
GCAGCTTTAGCAGAATATGTGAGTGAAAACATGCTACATCTTTATTGTATGTTAGCGGGCGAGAGAGTTATATACTTTAC
TGAACGCACTTCGTTTGTAGAAGATGCAGAAAAAATGGGTATGGATGCAGGATTAGAGTTAAAATCAAAATGCTTATAA

Protein sequence :
MLVKIGTRGSDLALIQALEAKQRLLESFPNLSVEIIKIKTSGDKYANVTLAEIGGKGLFLREIEAELLKNNIDMAVHSLK
DVPAFFSKDLTIPCVLERLSPCDVFISHKYKSLKTLPQQATIATSSIRRKVQLLNLRPDLNVVPLRGNVTTRLQNQNFDG
MILAEAGLIRLKKYHLITEVLPPKVMLSAVGQGTICIQCRKNDIKVIDLLEKINNNMSFIRAKSERSFMKTVNGSCFTPL
AALAEYVSENMLHLYCMLAGERVIYFTERTSFVEDAEKMGMDAGLELKSKCL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-42 45
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-42 45