Gene Information

Name : clpB (WPa_0355)
Accession : YP_001975152.1
Strain : Wolbachia endosymbiont wPip
Genome accession: NC_010981
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 375604 - 378165 bp
Length : 2562 bp
Strand : +
Note : -

DNA sequence :
ATGGACTTGAATAAATTTACCGAAAAAGCAAAAAGCCTAATCCAGAGAGCTCAAATGAAAGCATTGGGAGCTGGGCATCA
GATTTTTATGCCTGAACATTTACTTAAAGTAATGCTTGAAGATGAGTCAGGTTTAGTTCAGGATTTGATAGGCACCTGTG
GTGGAAATGTTCAGAATATTTCTGATGCTGTGAGTAGTACAATTAAAAAGTTTCCAGTGGTTGGAGGACCAGGTAGTGTT
GGACTTCAGCTTTCAAGAGAGGTAGCAAAAGTTTTTGATGATTCAATTGGTATTGCGAGGAAAAATAAAGACACATTTGT
TACTGTTGAGCGGTTGTTGCAGGGCCTTGCTGCACAAAAAGATGAAATTGTAGGTAAAATTTTAGCAGAAGGTGGTGTAA
CACCGCAAAAATTAAATTCAGTTATTGCAGAAATGAGAAAAGGTGGCAGTGCAGACTCTCCAAATAGCGAGGAAAAATTA
AATGCGGCAAAGAGGTATACAAAAGATATTACAGAGCTTGCTATGCAAGGTAAGCTTGATCCTGTAATTGGTCGTGATGA
GGAAATCAGAAGAACTATGCAGGTATCGTTGAGGCGAACAAAAAATAATCCAGTACTGATAGGTGAACCTGGTGTTGGAA
AAACTGCAATAGTTGAAGGTTTAGCAAACAGAATTGTTGCAAATGATGTACCACTTGGTTTGCGTGATGCAAAAGTTTTA
GCTTTGGATCTTGGTGCATTAATTGCTGGAACAAAATTTAGAGGGGAGTTTGAAGAGAGACTAAAAGCAGTGATTAATGA
GATTTTAAAAGCAGAGGGCAAAGTTATTTTGTTTATAGATGAGCTTCATACTTTAGTGGGAGCAGGAGCGACAAGTGGTG
CGATGGATGCTTCAAATTTGCTCAAGCCTGCTCTTGCGCGTGGAGAAATTCGCTGTATAGGGGCTACAACTTTGGATGAG
TATCGTCAACATATAGAGAAAGACCCTGCGCTTGCAAGGCGTTTTCAGCCTGTGTTTATTTCTCAACCGACTGAGACTGA
TACTATTTCAATACTGAGGGGTTTGAAGGAGAGGTATGAGGTGCACCATGGTATTAGAATCACAGATGGTGCAATAATCG
CTGCTGCAACGCTTTCTAATAGATATATAACAGATAGGTTTTTACCTGATAAAGCGATCGATTTAATTGATGAAGCAGCA
AGTAGGGTTAGAATTGAAATGGACAGCAAGCCTGAGGTTGTTGATGAGCTTGAAAGAAAGATTATACAGCTGAAAATTGA
GTCAGAGGCTTTGAAAAAAGAAAGTGATGAAAACTCTAAGCAACGTTTAAAAAAGATAAATGAGGAAATTGAGAGTCTAA
ACAGTAAATTTGCTGACTTAAGCAGTAAATGGCAGATGGAAAAGAATAAAATAGCTAAAATACAAGAAACTGCTGAAAAA
TTGGATAATGCGAGGAAAGAGCTAGAATTGGCTCAGCGGAATGGAAATTTAGGAAGGGCAGGGGAATTGATGTATGGTGT
GATTCCTCAACTTGAAAATGAGTTAAAAAATCAGGAAAAAGTTACTGATAGTTTCCTAAAGAAAGAAGTTACTGAGAGTG
ATATTGCAAATATTGTTTCAAAATGGACAGGCATTCCAGTTGATAACATGATGCATAGTGAAAAGGAAAAGCTCCTTAAC
ATGGAAAATGAAATAGGAAAAAGAGTAATAGGGCAGAGAGATGCAATTGAAGCGATAAGTAATGCAGTAAGGCGCTCCCG
TTCTGGTGTTCAGGATACTAATCGACCTTTTGGTTCATTTTTATTCTTAGGTCCAACCGGAGTTGGAAAAACAGAGTTAG
CAAAATCTCTTGCCGAATTTTTGTTTGATGATCAATCAGCACTTCTACGCTTTGATATGTCAGAGTATATGGAAAAACAC
TCCGTTTCAAAGTTAATTGGTGCGCCTCCAGGATATGTTGGTTATGAACAAGGTGGCAGATTAACCGAAGCAGTAAGGAG
AAGACCATATCAGGTAATTTTGTTTGATGAGATAGAAAAGGCAAATCCAGATATATTTAATATACTACTGCAGATTTTGG
ATGAAGGTAGACTAACCGATAGCCATGGCAAATTAATTGATTTTCGTAATACCATACTAATTTTAACTTCTAACCTTGGA
GCTGAGATGATGCTAAGAGGAGCTACCGAATCTGTGAAAGATGAGGTGATGAAAATAGTTAAGTCAGCGTTTCGTCCAGA
ATTTTTAAATAGACTGGATGAAATTATTATATTCCACAGCTTAACCAAAGATGACATTGATAAAATTATAGATGTTCAAT
TCTCTTATTTACAAAAGATGCTTGCTAAGCGTAAACTGAGTATTAGTTTATCGCAAGAAGCTAAAGGACTAATAGCACAA
ACTGGATATGACCCTGAATATGGAGCGCGGCCTCTGAAAAGGGTAATACAAGAATGCATTCAAAATAATCTAGCTAAGTT
AGTTTTATCTGGGGAAATAGTAGAAGGAGATGAGCTAATAGTGTATACTTCTGGTAACGAAATCTTAGTTAAAAAGATCT
AG

Protein sequence :
MDLNKFTEKAKSLIQRAQMKALGAGHQIFMPEHLLKVMLEDESGLVQDLIGTCGGNVQNISDAVSSTIKKFPVVGGPGSV
GLQLSREVAKVFDDSIGIARKNKDTFVTVERLLQGLAAQKDEIVGKILAEGGVTPQKLNSVIAEMRKGGSADSPNSEEKL
NAAKRYTKDITELAMQGKLDPVIGRDEEIRRTMQVSLRRTKNNPVLIGEPGVGKTAIVEGLANRIVANDVPLGLRDAKVL
ALDLGALIAGTKFRGEFEERLKAVINEILKAEGKVILFIDELHTLVGAGATSGAMDASNLLKPALARGEIRCIGATTLDE
YRQHIEKDPALARRFQPVFISQPTETDTISILRGLKERYEVHHGIRITDGAIIAAATLSNRYITDRFLPDKAIDLIDEAA
SRVRIEMDSKPEVVDELERKIIQLKIESEALKKESDENSKQRLKKINEEIESLNSKFADLSSKWQMEKNKIAKIQETAEK
LDNARKELELAQRNGNLGRAGELMYGVIPQLENELKNQEKVTDSFLKKEVTESDIANIVSKWTGIPVDNMMHSEKEKLLN
MENEIGKRVIGQRDAIEAISNAVRRSRSGVQDTNRPFGSFLFLGPTGVGKTELAKSLAEFLFDDQSALLRFDMSEYMEKH
SVSKLIGAPPGYVGYEQGGRLTEAVRRRPYQVILFDEIEKANPDIFNILLQILDEGRLTDSHGKLIDFRNTILILTSNLG
AEMMLRGATESVKDEVMKIVKSAFRPEFLNRLDEIIIFHSLTKDDIDKIIDVQFSYLQKMLAKRKLSISLSQEAKGLIAQ
TGYDPEYGARPLKRVIQECIQNNLAKLVLSGEIVEGDELIVYTSGNEILVKKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-163 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_001975152.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG0079 Protein 2e-149 42
clpB YP_001975152.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG2084 Protein 3e-104 41