Gene Information

Name : pykA (Smlt3798)
Accession : YP_001973493.1
Strain : Stenotrophomonas maltophilia K279a
Genome accession: NC_010943
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3876559 - 3878025 bp
Length : 1467 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGTTCGAGCGTCAGCGTCGCACCAAGATCCTTGCCACCCTCGGTCCGGCCACTGATCCGCCGGGCGTGCTGGAGGATCT
GTTCCGCGCCGGCGTCAACGTGGTGCGCCTCAACTTCAGCCATGGTGACCCGTCCGGCCAGGCCAAGCGTGCCGCCGAAG
TGCGTGCCGCCGCCGCCCGCGTCGGCGTGGAAGTGGGCATCCTGGCCGACCTGCCGGGCCCGAAGATCCGCATCGAGCGC
TTCGCAGAAGGCAAGGTGCAGCTGAAGGCGGGCAACCGCTTCGACCTGATCGCCAGCACCAGCGCCGGCCCGGGTGATGC
CACCCAGGTGGGTGTGAGCTACCTCGGCCTGCCGCAGGACGTGGGTCCGGGCGATGTCCTGCTGCTCGACGACGGCCTGA
TGCAGCTGCAGGTGGTGGAGGTGCAGGGCGAACGCATCATCAATACCGTACTGAACGACGGTGTGCTGTCCGACCGCAAG
GGCCTGAACAAGCAGGGCGGCGGCCTCTCGCTGGGCGCGCTGACCGAGCGCGACAAGGAACTGATCGGCATCGTCGCCAA
GATCGGTGTCGACTTCATCGCTGTGTCGTTCTGCCGCAACGCGCAGGACATGAACGATGCGCGTGACATCGCCCGCTCGC
ATGGCTGTGATGCTGCACTGGTATCGAAGATCGAGCGCACCGAGGCCATCGAGAACCTGGAAGAAATCGTCGAGGCCAGC
GACGTGGTGATGGTCGCCCGTGGCGACCTTGGCGTGGAGATCGGCGATGCCGAACTGCCGGGCCTGCAGAAGAAGATCAT
CAAGGCCTCGCTGGCACAGAACAAGGTGGTGATCACCGCCACGCAGATGCTGCAGTCGATGGTGGAAAGCCCGATTCCGA
CCCGTGCCGAAGTGCTGGACGTGGCCAACTCGGTCATCGACGGCACCGATGCGGTGATGCTGTCGGCCGAGACTGCTGCA
GGTGCCTGGCCGGTCAAGGCGGTCGAAGCAATGGCGCGCATCTGCCTGGGGGCCGAGCGCCAGTTCCAGACCGAGACCGA
CTTCAACGCTTCGCCGCGCAACCTCGAGCGTGCCGACCAGGCCATTGCCATGGCCACCATGTTCCTGTCCCAGCACGTGG
GCGTGCGCGCGATCGTGGCAATGACCGAGTCCGGTGGCACCGCGCGTTACCTGTCGCGTTTCCGCGCCAAGGCGCCGGTG
TTCGCGGTGACCCGCCATGACGGCGCGCGCCGGCAGATGGCGCTGATGCGCGATGTGTTCCCGATCAACTTCGACAGCCG
CGGCCTGACCCCGCGCGAAGCCGCGCGCGGCAGCATCCGCCTGCTGGTGGAAGCCGAACTGCTGCAGGCCGGCGACCGCG
TCGTGTTCACCAGCGGCGAGCACATGGAAACCCACGGTGCCACCAATACCCTGCGCCTGCTGGAAGTGGGTGAAGACGGC
CGCGCCATTGGGCTGGGCGATCTGTAA

Protein sequence :
MFERQRRTKILATLGPATDPPGVLEDLFRAGVNVVRLNFSHGDPSGQAKRAAEVRAAAARVGVEVGILADLPGPKIRIER
FAEGKVQLKAGNRFDLIASTSAGPGDATQVGVSYLGLPQDVGPGDVLLLDDGLMQLQVVEVQGERIINTVLNDGVLSDRK
GLNKQGGGLSLGALTERDKELIGIVAKIGVDFIAVSFCRNAQDMNDARDIARSHGCDAALVSKIERTEAIENLEEIVEAS
DVVMVARGDLGVEIGDAELPGLQKKIIKASLAQNKVVITATQMLQSMVESPIPTRAEVLDVANSVIDGTDAVMLSAETAA
GAWPVKAVEAMARICLGAERQFQTETDFNASPRNLERADQAIAMATMFLSQHVGVRAIVAMTESGGTARYLSRFRAKAPV
FAVTRHDGARRQMALMRDVFPINFDSRGLTPREAARGSIRLLVEAELLQAGDRVVFTSGEHMETHGATNTLRLLEVGEDG
RAIGLGDL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 5e-69 47
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-58 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-58 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-58 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-58 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_001973493.1 pyruvate kinase VFG0479 Protein 5e-59 41