Gene Information

Name : merA (Smlt2412)
Accession : YP_001972199.1
Strain : Stenotrophomonas maltophilia K279a
Genome accession: NC_010943
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 2444312 - 2446006 bp
Length : 1695 bp
Strand : +
Note : similarity:fasta; SCO3460; scoelicolor; putative oxidoreductase; length 505 aa; id=36.1%; E()=1.4e-34; 462 aa overlap; query 93-544 aa; subject 26-473 aa; similarity:fasta; DIP0645; cdiphtheriae; Dihydrolipoamide dehydrogenase; length 490 aa; id=31.8%; E(

DNA sequence :
ATGACCGAGGCGATCACGCTGCACATCGATGGCATGACCTGCGGGTCGTGCGCCGAGCACGTCAAGCAGACCTTGGAAAA
GGTGCCCGGCGTGCGTTCGGCCTCAGTGTCCTACCCACAGCGCCGGGCCGAGATTGAGGCCAGCGTAGGTACCGCCGCGG
ACGTGACCTCGCTGGTCGCGGCGGTATCCGCACTCGGTTACCGAGCGCAGCTTGCCGATGCGCCGGGGCAACCCAGCGAC
CTGCTGAACAATGCACAAGAGCGGCTGGGCGGCGAACCAAAGCGCGAGGACGATGAGGCTGCACTGCACGTGGCCGTGAT
CGGCAGCGGCGGCGCGGCGATGGCGGCGGCGTTGAAGGCCGTCGAGCAAGGGGCGCGTGTGACGCTGATCGAGCGCAGCA
CTCTCGGCGGCACCTGCGTCAACGTCGGATGTGTGCCGTCCAAGATCATGATCCGCGCTGCCCACATTGCGCATCTGCGT
CGCGAGAGTCCGTTCGATGACGGCATTGCCGCCGCCTCGCCGAAGATTCTGCGCAAGCGCTTGCTGGCTCAGCAGCAGGG
GCGCGTCGATGAACTGCGCCACGCCAAGTACGAAGGCATCCTGACGAGCACCCCGACCATCACCGTGCTGCGCGGCGATG
CCCGATTCAAGGATGCGCACACGCTGACCGTGGCAACCGCTGACGACGGGATGCGCGAGGTGAGTTTCGACCGCTGCCTC
ATCGCCACCGGGGCCAGTCCGGCGATTCCACCGATCCCGGGCTTGAAAGACACGCCCTTCTGGACGTCGACCGAAGCGCT
GGCCAGCGACACGATCCCCGATCGGCTGGCCGTGATCGGCTCGTCGGTGGTGGCCGTCGAACTCGCGCAGGCCTTTGCCC
GGCTGGGCAGCAAGGTGACCATGCTGGCGCGCAGCACACTGTTCTTTCGCGAAGACCCCGCCATTGGCGAGGCCATCACG
GCCGTGTTCCGCGCCGAAGGCATCGAAGTGCTGGACCACACCCAGGCCAGCCAGGTCGCCTATGAGGATGGGGAATTCGT
GCTCACCACCGAACGCGGCGAACTGCATGCCGACCGGCTGTTGTTCGCCACCGGCCGCACCCCAAACACCCGCACGCTCA
ACCTCGACGCGGCCGGTGTGGTGGTCAATGCGCAAGGCGCCATCACCATCGACCACGCGATGCGCACTACCGTGCCGCAC
ATCTATGCCGCCGGCGACTGCACTGACCAGCCGCAGTTCGTCTACGTCGCGGCGGCGGCCGGCACCCGCGCTGCAATCAA
CATGACGGGTGGCAACGCGACGCTGGATCTGACGGCGATGCCGGCGGTGGTGTTCACCGACCCGCAGGTCGCCACCGTGG
GCTACAGCGAAGCCGAAGCGCACCACGACGGTATCGAGACCGACAGCCGCACGCTGACGCTCGACAACGTGCCCCGGGCG
CTGGTCAACTTCGACACGCGCGGTTTCATCAAGCTGGTTTCGGAGGCCGGTTCGGGACGACTGATCGGCGTGCAAGCGGT
AGCCCCGGAAGCAGGCGAGCTGATCCAAACCGCAGTACTGGCGATTCGCAACCGCATGACGGTGCGAGAGTTGGCCGACC
AGTTATTCCCCTACCTGACGATGGTCGAGGGGCTGAAACTCGCGGCACAAACCTTCACCAAGGACGTAAAGCAACTGTCC
TGTTGCGCGGGGTAG

Protein sequence :
MTEAITLHIDGMTCGSCAEHVKQTLEKVPGVRSASVSYPQRRAEIEASVGTAADVTSLVAAVSALGYRAQLADAPGQPSD
LLNNAQERLGGEPKREDDEAALHVAVIGSGGAAMAAALKAVEQGARVTLIERSTLGGTCVNVGCVPSKIMIRAAHIAHLR
RESPFDDGIAAASPKILRKRLLAQQQGRVDELRHAKYEGILTSTPTITVLRGDARFKDAHTLTVATADDGMREVSFDRCL
IATGASPAIPPIPGLKDTPFWTSTEALASDTIPDRLAVIGSSVVAVELAQAFARLGSKVTMLARSTLFFREDPAIGEAIT
AVFRAEGIEVLDHTQASQVAYEDGEFVLTTERGELHADRLLFATGRTPNTRTLNLDAAGVVVNAQGAITIDHAMRTTVPH
IYAAGDCTDQPQFVYVAAAAGTRAAINMTGGNATLDLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRTLTLDNVPRA
LVNFDTRGFIKLVSEAGSGRLIGVQAVAPEAGELIQTAVLAIRNRMTVRELADQLFPYLTMVEGLKLAAQTFTKDVKQLS
CCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 83
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 80
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 80
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 80
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 79
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 79
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 79
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 79
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 79
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 74
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 5e-84 41
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 3e-84 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_001972199.1 mercuric reductase BAC0653 Protein 0.0 80
merA YP_001972199.1 mercuric reductase BAC0652 Protein 0.0 79
merA YP_001972199.1 mercuric reductase BAC0650 Protein 1e-178 69
merA YP_001972199.1 mercuric reductase BAC0651 Protein 2e-84 41