Gene Information

Name : guaA (Smlt2072)
Accession : YP_001971878.1
Strain : Stenotrophomonas maltophilia K279a
Genome accession: NC_010943
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2097062 - 2098627 bp
Length : 1566 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCAACATCCATAACGACAAGATCCTCATCCTCGATTTCGGCGCGCAGTACACGCAGCTGATCGCCCGCCGCATCCG
CGAGCTGGGCGTCTACTGCGAAATCTGGGCGTGGGACCACAACCCGGCCGAGATCGCCGGCTTCGGCGCCAAGGGCATCA
TCCTGTCCGGTGGCCCGGAATCGACCACGCTGCCGGGTGCGCCGGCCGCGCCGCAGGAAGTGTTCGACAGCGGCCTGCCG
ATCTTCGGCATCTGCTACGGCATGCAGACCCTGGCCGCGCAGCTGGGCGGTGCCACCGAAGCGGCGGATCAGCGCGAGTT
CGGCCACGCCGAAGTGAACGTGATCAACCCGGATGCACTGTTCAAGGGCCTGAGCGACCACGGCGGCGAGCCGAAGCTGA
ATGTCTGGATGAGCCACGGCGACCACGTCTCCGTTGCACCGCCGGGCTTCACCATCACCGCCACCACCGACCGCATTCCG
GTGGCCGCCATGGCCAACGAAGAAAAGCGCTGGTACGGCGTGCAGTTCCACCCGGAAGTGACCCACACCCTGCAGGGCCA
GGCGCTGCTGCGCCGCTTCGTGGTGGACGTGTGCGGTTGCCAGACCCTGTGGACCGCCGCCAACATCATCGACGACCAGA
TCGCCCGCGTGCGCGAACAGGTGGGCGATGACGAAGTGATCCTGGGCCTGTCCGGCGGCGTCGATTCGTCCGTGGTGGCT
GCGCTGCTGCACAAGGCCATCGGCGAGAAGCTGACCTGCGTGTTCGTGGATACCGGCCTGCTGCGCTGGCAGGAAGGCGA
CCAGGTGATGGCGATGTTTGCCGAGCACATGGGCGTAAAGGTGGTGCGCGTGAATGCCGCCGACCGTTACTTCGCCGCGC
TGGAAGGCGTGAGCGACCCGGAAGCCAAGCGCAAGATCATCGGCAACCTGTTCGTTGAGATCTTCGACGAAGAATCGAAC
AAGCTGAAGAACGCCAAGTGGCTGGCGCAGGGCACCATCTACCCGGACGTGATCGAGTCGGCCGGCAGCAAGACCGGCAA
GGCGCATGTGATCAAGAGCCACCACAACGTGGGCGGCCTGCCGGAGCACATGAAGCTGGGCCTGGTGGAGCCGCTGCGGG
AGCTGTTCAAGGACGAAGTGCGTCGCCTGGGCGTCGAGCTCGGCTTGCCGCGCACCATGGTCTACCGCCATCCGTTCCCG
GGCCCGGGCTTGGGCGTGCGTATTCTGGGCGAAGTGAAGCGCGAATACGCCGAACTGCTGGCCAAGGCCGATGCCATCTT
CATTGATGAGCTGCGCAAGGCCGACCTGTACGACAAGACCAGCCAGGCGTTTGCCGTGTTCCTGCCGGTGAAGTCGGTGG
GCGTGGTGGGCGATGCGCGCGCTTATGAGTGGGTGATTGCGCTGCGTGCGGTGGAGACGATCGACTTCATGACGGCGCAT
TGGGCGCATCTGCCGTATGAGTTCCTGGGGACGGTGAGCAACCGGATCATCAATGAGTTGCGGGGGGTGTCACGGGTTGT
CTATGACATCTCGGGGAAGCCGCCGGCTACTATTGAGTGGGAATGA

Protein sequence :
MTNIHNDKILILDFGAQYTQLIARRIRELGVYCEIWAWDHNPAEIAGFGAKGIILSGGPESTTLPGAPAAPQEVFDSGLP
IFGICYGMQTLAAQLGGATEAADQREFGHAEVNVINPDALFKGLSDHGGEPKLNVWMSHGDHVSVAPPGFTITATTDRIP
VAAMANEEKRWYGVQFHPEVTHTLQGQALLRRFVVDVCGCQTLWTAANIIDDQIARVREQVGDDEVILGLSGGVDSSVVA
ALLHKAIGEKLTCVFVDTGLLRWQEGDQVMAMFAEHMGVKVVRVNAADRYFAALEGVSDPEAKRKIIGNLFVEIFDEESN
KLKNAKWLAQGTIYPDVIESAGSKTGKAHVIKSHHNVGGLPEHMKLGLVEPLRELFKDEVRRLGVELGLPRTMVYRHPFP
GPGLGVRILGEVKREYAELLAKADAIFIDELRKADLYDKTSQAFAVFLPVKSVGVVGDARAYEWVIALRAVETIDFMTAH
WAHLPYEFLGTVSNRIINELRGVSRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-125 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-125 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-125 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-113 49