Gene Information

Name : thyA (Smlt0813)
Accession : YP_001970703.1
Strain : Stenotrophomonas maltophilia K279a
Genome accession: NC_010943
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 854942 - 855736 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAGGCTTACCTGGACCTGCTCTCGCATGTGCTCGAGCACGGCGCCGAGAAGAGCGACCGCACCGGCACCGGTACCCG
CAGCGTGTTCGGCTGGCAGATGCGTTTCAACCTGGCCGACGGCTTCCCGCTGGTCACCACCAAGAAGCTGCACCTGCGCT
CGATCATCCACGAGCTGCTGTGGTTCCTGAAGGGCGACACCAACATCGGCTACCTGAAGGACAACCAGGTGCGGATCTGG
GACGAGTGGGCCGACGAGAACGGCGATCTCGGCCCGGTGTACGGCAAGCAGTGGCGCAGCTGGGCCACCGCCGATGGCCG
TGAGATCGATCAGATGCAGTGGCTGGTCGACGAGATCAAGCGCAACCCCGATTCGCGGCGGCTGGTGGTCAGCGCCTGGA
ACGTGGGCGAGCTTTCGCAGATGGCGCTGATGCCGTGCCACAACCTGTTCCAGTTCTACGTGGTGGACGGCAAGCTCAGC
TGCCAGCTGTACCAGCGCAGCGGCGACATCTTCCTCGGCGTGCCGTTCAACATCGCCAGCTACGCGCTGCTGACCCACAT
GGTGGCGCAGGCCACCGGCCTGGGCGTGGGCGATTTCGTGCATACGCTGGGCGACGCGCACCTGTATTCGAACCACTTCG
AGCAGGCGCGCGAGCAGCTGTCGCGTGAACCGCGCGCGCTGCCCAAGCTGTGGTTGAACCCGGAGGTGACCGATCTGTTC
GGCTTCCAGTTCGACGACATCCGCATCGACGGTTACGATCCGCACCCGGCCATCAAGGCGCCGGTGGCGGTATGA

Protein sequence :
MKAYLDLLSHVLEHGAEKSDRTGTGTRSVFGWQMRFNLADGFPLVTTKKLHLRSIIHELLWFLKGDTNIGYLKDNQVRIW
DEWADENGDLGPVYGKQWRSWATADGREIDQMQWLVDEIKRNPDSRRLVVSAWNVGELSQMALMPCHNLFQFYVVDGKLS
CQLYQRSGDIFLGVPFNIASYALLTHMVAQATGLGVGDFVHTLGDAHLYSNHFEQAREQLSREPRALPKLWLNPEVTDLF
GFQFDDIRIDGYDPHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 3e-80 66