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Name : APP7_0788 (APP7_0788) Accession : YP_001968582.1 Strain : Actinobacillus pleuropneumoniae AP76 Genome accession: NC_010939 Putative virulence/resistance : Unknown Product : DNA topoisomerase 3 Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : 5.99.1.2 Position : 876690 - 878627 bp Length : 1938 bp Strand : - Note : - DNA sequence : ATGATATCAGAGAAAAGAATTTTGAGAGTATTTTTAGCGGAAAAACCGAGTTTGGCAAGAGCAATCGCAGACGTATTGCC GAAGCCGCATACCCGTGGTGACGGCTATATTCAATGTGGTGAAAATGATACGGTAACTTGGTGTATCGGTCATTTATTGG AACAAGCGGAACCTGATATTTACGACGAACGTTTTAAAATGTGGCGAATGGAGCATTTGCCGATTGTCCCGCAGCAATGG AAATTAGTGCCGAAAAAAGAAACGTTGAAGCAGTTAAAAGCGGTCGAAAAATTGGTAAAAAAAGCGGACGTATTGGTAAA CGCCGGCGACCCGGACCGAGAAGGGCAGCTATTAGTTGATGAGGTCTTTAGCTATCTGAACGTACCGCCGGAAAAACGTA ATCGGATTCAACGTTGTTTGGTGAGCGATCTCAACCCGAGTGCGGTAAAAAAAGCGATTGATAAATTGCAAAATAATCGT GATTTTATACCGCTTGCCACCTCTGCCTTAGCACGTGCAAGAGCCGATTGGCTATACGGCATTAATATGACGCGAGCTTA TACCTTACAAGGACGTTGGGCGGGCTATCAGGGGGTATTGTCGGTGGGGCGTGTTCAAACCCCCGTGTTAGGTTTAATTG TGCGCCGCGATCTGGAAATAGAAAACTTTGTGCCGAAAGACTATTTTGAAGTATTGGCGCATATCGTTGTGCCGGAAACT CAAGAACGTTTTACTGCCCAATGGCAACCGAGTAAGGCGTGCGAAGATTATCAAGATGAAGACGGTCGAGTATTATCTAA AAGTTTGGCGGAAAATGTCGTTAAACGCATTACCGACCAAGCAGCATTAGTAACGGATTATCAAGATAAAATTGAAACGG AAACCGCACCGCTGCCTTATTCATTATCGGTATTACAAATTGATGCGGCACGCCGTTACGGCCTATCGGCACAAGCTGTG TTGGATATTTGTCAGAAACTGTATGAAACGCATAAGCTGATTACCTATCCCCGTTCGGATAACCGTTATCTACCGAATGA GCATTACGCTGATCGTTTTAAAGTGATGGCGGCGATTGCACATCATCTGGATGAGTATAAAGAAAAACCGGAGGCGGTTA ATCCGGAAATTCGTAATCGTTGTTGGAATGATAAAAAGGTAGAAGCGCACCATGCTATTATTCCGACCGTACGCCAAGGC TCGGTAAAACTAACTGAAAACGAAAAGCGTATTTATCAACTGATTGCCCGTCAATACTTAATGCAATTTTGTCCGGATGC GGAATATCGCAAAGGTAAAATTGTATTGGAGATTGCCGGAGGAACCTTTAACGCACAGGCTCGGAACTTAATTGTTGCCG GTTGGAAAGCATTATTAGGCAAAGAAGACAGTGACGAAGTGTTAGAGCCGTTATTACCGGTTATGAAAAAAGGGCAGCAA TTACATTGTGAAAAAGGTGAGATTGTCAGTAAGAAAACCCAGCCGCCTCGTCATTTTACCGACGCAAGTTTATTATCGGC AATGACCGGCATCGCTCGTTTCGTACAAGATAAACAACTTAAAAAAGTCTTACGTGAAACGGACGGCTTAGGTACTGAAG CAACACGTGCCGGTATTATCGAATTGCTGTTTAAACGCGGATTTTTAATCAAAAAAGGACGAAATATCCACAGTACGGAA GCCGGGCGAATTCTAATTAGTGCCTTACCGGACGAAGCGACTCAGCCGGATATGACTGCGCATTGGGAAATGCAACTTAC CGACATTAGTAAGAAGCAAGCGAGTTATCAGCAGTTTATGCAAGTACTTACGAGTAAATTACCTGAGTTATTACATACGG AACGACAAAAATTGCAAAATTTAAGTCGAATTCAACCGCCCGCCTCTTATCGTAAGCGGTCAAATTTTAAGAAAAATTTA CAAACTGCTGAAAAATAA Protein sequence : MISEKRILRVFLAEKPSLARAIADVLPKPHTRGDGYIQCGENDTVTWCIGHLLEQAEPDIYDERFKMWRMEHLPIVPQQW KLVPKKETLKQLKAVEKLVKKADVLVNAGDPDREGQLLVDEVFSYLNVPPEKRNRIQRCLVSDLNPSAVKKAIDKLQNNR DFIPLATSALARARADWLYGINMTRAYTLQGRWAGYQGVLSVGRVQTPVLGLIVRRDLEIENFVPKDYFEVLAHIVVPET QERFTAQWQPSKACEDYQDEDGRVLSKSLAENVVKRITDQAALVTDYQDKIETETAPLPYSLSVLQIDAARRYGLSAQAV LDICQKLYETHKLITYPRSDNRYLPNEHYADRFKVMAAIAHHLDEYKEKPEAVNPEIRNRCWNDKKVEAHHAIIPTVRQG SVKLTENEKRIYQLIARQYLMQFCPDAEYRKGKIVLEIAGGTFNAQARNLIVAGWKALLGKEDSDEVLEPLLPVMKKGQQ LHCEKGEIVSKKTQPPRHFTDASLLSAMTGIARFVQDKQLKKVLRETDGLGTEATRAGIIELLFKRGFLIKKGRNIHSTE AGRILISALPDEATQPDMTAHWEMQLTDISKKQASYQQFMQVLTSKLPELLHTERQKLQNLSRIQPPASYRKRSNFKKNL QTAEK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 3e-109 | 41 |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 5e-109 | 41 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 5e-109 | 41 |
