Gene Information

Name : APP7_0723 (APP7_0723)
Accession : YP_001968517.1
Strain : Actinobacillus pleuropneumoniae AP76
Genome accession: NC_010939
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 807068 - 808204 bp
Length : 1137 bp
Strand : -
Note : -

DNA sequence : 
ATGACCAAATACAGTAACATTGAAACCACATTAGTACAGTTAGGCAACCGCACCGACCCTAGAACGGGAGCGGTAGCCAC
ACCGATTGTTTTATCGACCGCTTATGGTCGTGACGGTTTGGGCGAATCGACCGGTTGGGATTATATTCGTACCAAAAACC
CGACCCGTGCCGTGTTAGAGCAAGGTATTGCAGATTTAGAGGGCGGTGATGCAGGTTTCGCAATGGCATCAGGTATGGCG
GCAATTCAGTTAGTGATGTCATTGTTTAAAGCGCCTGATGAGTGGATTATTTCAAGTGATGTATATGGCGGCTCTTACCG
TTTATTCGATTTCAGTCATAAACACCACAATACAGTAAAACCGGTTTATGTAAATACCGCAGATTTGGCGGCGGTTGAAG
CGGCAATTACCCCAAACACTAAAGCGATTTTTGTTGAAACACCGTCAAACCCATTAATGGAAGAGTGTGATGTTGATGCA
ATTTCTAAAATTGCGAAAAAACATAACTTAATGTTAATTGTGGATAATACCTTCTTAACGCCGATTTTATTCCGTCCGAT
TGAACACGGTGCGGATATCGTGATTCACAGTGCAACGAAATACCTTTCCGGTCATAATGATGTGTTAGCCGGTTTAATCG
TTGCGAAAGATTCGGAAGCAACCAAAAACGAAGCGGGTCAAAAGCTTTCGGAACGTTTATTCTACTTCCAAAACTGTGCC
GGTGCGGTGCTTTCGCCGTTTGATTCTTACCTTGCGGTGCGTGGCTTAAAAACCCTTGCGTTACGTATGGAACGCCACCA
ATCGAATGCTACGGAATTAGCGAGATTCTTAAGCGAGCAACCGGAGATTGAGAGCGTACTTTATTCAGGTAAGAGCGGTA
TGCTTTCATTCCGTTTACAAAAAGAAGAGTGGGTACCGAAATTCTTAAAAGCGATTAAGTTGATTACCTTTGCGGAAAGT
TTAGGCGGTACGGAAAGTTTTATCACTTATCCGTCCACTCAAACACATATGGATATTCCGGAAGCGGAGCGTATTGCACG
TGGTATCACCAATAACTTACTGCGTTTCTCAGTTGGCTTGGAACATGTTGAAGATTTAAAAGCGGATTTACGCCAAGCGT
TCGGACAACTAAAATAA

Protein sequence : 
MTKYSNIETTLVQLGNRTDPRTGAVATPIVLSTAYGRDGLGESTGWDYIRTKNPTRAVLEQGIADLEGGDAGFAMASGMA
AIQLVMSLFKAPDEWIISSDVYGGSYRLFDFSHKHHNTVKPVYVNTADLAAVEAAITPNTKAIFVETPSNPLMEECDVDA
ISKIAKKHNLMLIVDNTFLTPILFRPIEHGADIVIHSATKYLSGHNDVLAGLIVAKDSEATKNEAGQKLSERLFYFQNCA
GAVLSPFDSYLAVRGLKTLALRMERHQSNATELARFLSEQPEIESVLYSGKSGMLSFRLQKEEWVPKFLKAIKLITFAES
LGGTESFITYPSTQTHMDIPEAERIARGITNNLLRFSVGLEHVEDLKADLRQAFGQLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-63 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-64 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APP7_0723 YP_001968517.1 cystathionine gamma-synthase BAC0207 Protein 2e-51 43