Gene Information

Name : APP7_0367 (APP7_0367)
Accession : YP_001968161.1
Strain : Actinobacillus pleuropneumoniae AP76
Genome accession: NC_010939
Putative virulence/resistance : Resistance
Product : tetracycline resistance protein, class G
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 415807 - 416946 bp
Length : 1140 bp
Strand : -
Note : -

DNA sequence : 
ATGCCAGTCTTGCCAACGTTATTACGTGAATTTATTGCTTCGGAAGATATCGCTAACCACTTTGGCGTATTGCTTGCACT
TTATGCGTTAATGCAGGTTATCTTTGCTCCTTGGCTTGGAAAAATGTCTGACCGATTTGGTCGGCGCCCAGTGCTGTTGT
TGTCATTAATAGGCGCATCGCTGGATTACTTATTGCTGGCTTTTTCAAGTGCGCTTTGGATGCTGTATTTAGGCCGTTTG
CTTTCAGGGATCACAGGAGCTACTGGGGCTGTCGCGGCATCGGTCATTGCCGATACCACCTCAGCTTCTCAACGCGTGAA
GTGGTTCGGTTGGTTAGGGGCAAGTTTTGGGCTTGGTTTAATAGCGGGGCCTATTATTGGTGGTTTTGCAGGAGAGATTT
CACCGCATAGTCCCTTTTTTATCGCTGCGTTGCTAAATATTGTCGCTTTCCTTGTGGTTATGTTTTGGTTCCGTGAAACC
AAAAATACACGTGATAATACAGATACCGAAGTAGGGGTTGAGACGCAATCGAATTCGGTATACATCACTTTATTTAAAAC
GATGCCCATTTTGTTGATTATTTATTTTTCAGCGCAATTGATAGGCCAAATTCCCGCAACGGTGTGGGTGCTATTTACCG
AAAATCGTTTTGGATGGAATAGCATGATGGTTGGCTTTTCATTAGCGGGTCTTGGTCTTTTACACTCAGTATTCCAAGCC
TTTGTGGCAGGAAGAATAGCCACTAAATGGGGCGAAAAAACGGCAGTACTGCTCGGATTTATTGCAGATAGTAGTGCATT
TGCCTTTTTAGCGTTTATATCTGAAGGTTGGTTAGTTTTCCCTGTTTTAATTTTATTGGCTGGTGGTGGGATCGCTTTAC
CTGCATTACAGGGAGTGATGTCTATCCAAACAAAGAGTCATCAGCAAGGTGCTTTACAGGGATTATTGGTGAGCCTTACC
AATGCAACCGGTGTTATTGGCCCATTACTGTTTGCTGTTATTTATAATCATTCACTACCAATTTGGGATGGCTGGATTTG
GATTATTGGTTTAGCGTTTTACTGTATTATTATCCTGCTATCGATGACCTTCATGTTAACCCCTCAAGCTCAGGGGAGTA
AACAGGAGACAAGTGCTTAG

Protein sequence : 
MPVLPTLLREFIASEDIANHFGVLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSPFFIAALLNIVAFLVVMFWFRET
KNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYFSAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQA
FVAGRIATKWGEKTAVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGALQGLLVSLT
NATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQAQGSKQETSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA(B) AAL08445.1 tetracycline resistance protein TetA(B) Not tested SRL Protein 3e-154 100
tetA YP_005797160.1 tetracycline resistance protein, class G (TETA(G)) Not tested AbaR4e Protein 5e-153 99
tetA(B) AEZ06045.1 tetracycline efflux protein Not tested Tn6167 Protein 4e-154 99
tetB AEA34667.1 tetracycline resistance determinant Not tested Not named Protein 3e-154 99
BJAB07104_00277 YP_008207742.1 Permeases of the major facilitator superfamily Not tested AbaR25 Protein 1e-153 99
BJAB0868_00281 YP_008211607.1 Permeases of the major facilitator superfamily Not tested AbaR26 Protein 1e-153 99
tetA(B) AEQ20905.1 tetracycline resistance protein Not tested Tn6166 Protein 1e-153 99
ABZJ_00260 YP_005524216.1 Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) Not tested AbaR22 Protein 7e-154 99
tetA(B) AFH57202.1 tetracycline resistance protein Not tested AbaR4a Protein 7e-154 99
tet(H) YP_005176248.1 tetracycline efflux protein, class H Not tested ICEPmu1 Protein 4e-73 53
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 5e-79 51
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 5e-79 51
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 5e-79 51
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 5e-79 51
tetA CAJ77034.1 Tetracycline resistance protein Not tested AbaR1 Protein 3e-79 51
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 4e-66 48
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 3e-66 48
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 3e-66 48
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 3e-66 48
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 2e-66 48
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 1e-66 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G NC_010558.1.6275971. Protein 2e-154 100
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G V00611.gene.p01 Protein 4e-153 99
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AB084246.gene.p01 Protein 2e-154 99
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G L06798.gene.p01 Protein 1e-83 60
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AJ250203.gene.p01 Protein 6e-77 58
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G Y19116.gene.p01 Protein 8e-74 54
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G L06940.gene.p01 Protein 1e-73 54
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G Y15510.gene.p01 Protein 7e-74 53
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AF038993.gene.p01 Protein 5e-73 53
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G CP004022.1.gene2534. Protein 6e-73 53
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G NC_010410.6002612.p0 Protein 2e-79 51
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AF133140.gene.p01 Protein 2e-79 51
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AF133139.gene.p01 Protein 2e-78 51
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G NC_011586.7045189.p0 Protein 3e-66 48
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G Y19114.gene.p01 Protein 2e-65 48
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AF534183.gene.p01 Protein 8e-67 48
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G NC_010410.6002597.p0 Protein 9e-67 48
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G CP001485.1.gene2821. Protein 9e-67 48
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G X75761.gene.p01 Protein 5e-66 47
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AF121000.gene.p01 Protein 6e-59 45
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AF070999.gene.p01 Protein 5e-63 45
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AY264780.2.gene3.p01 Protein 1e-57 43
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AJ420072.gene.p01 Protein 1e-55 43
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G AY743590.gene.p01 Protein 1e-54 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APP7_0367 YP_001968161.1 tetracycline resistance protein, class G VFG1036 Protein 1e-154 100