Gene Information

Name : APP7_0274 (APP7_0274)
Accession : YP_001968068.1
Strain : Actinobacillus pleuropneumoniae AP76
Genome accession: NC_010939
Putative virulence/resistance : Virulence
Product : iron (chelated) ABC transporter periplasmic- binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 307331 - 308227 bp
Length : 897 bp
Strand : -
Note : -

DNA sequence : 
ATGAAACTTTCATTTTTAAAACAAGTATTTGTGGTTGCATTAGGTTTAAGCGCAACACTCGCTATGGCTGCGCCATTCAA
AGTCGTCACAACATTTACCGTGATCCAAGATATTGCGCAAAATGTTGCCGGTGATAAAGCGGTTGTCGAATCCATAACTA
AGCCAGGTGCGGAAATTCATGATTACCAACCGACACCGAAAGATATTGCTAAAGCACAAAAAGCGGATCTTATCTTATGG
AACGGTATGAATTTAGAACGTTGGTTCGAACGTTTCTTTGAAAATGTAAAAGGTAAACCGGCCGTTGTGGTAACCGAAGG
CATCACACCAATTGCAATTACTGAAGGTGAATATAAAAACTTACCGAACCCGCATGCTTGGATGTCATCGGCTAATGCAT
TGCAATATATTGAAAATATTCGTGCCGCATTAGTGAAATACGATCCGAAAAATGCCGAAAGCTATAACCAAAATGCTAAA
GTTTATGCAGAAAAAGTAAAAGAAATTGCCGAACCGTTACGCCAACGTCTATCCGTTATTCCGGAAGCACAACGTTGGTT
AGTAACCAGTGAAGGTGCATTCAGTTATTTAGCACAGGACTATCAATTAAAAGAGCTTTATCTCTGGGCAATTAATGCTG
AAGAGCAAGGCTCGCCGCAACAAGTGAAAAAAGTAATTGACGGTGTAAAAGCCAACAATATCCCTGTTGTTTTCAGCGAA
AGCACCGTATCGGATAAACCGGCTAAACAAGTTGCTAAAGAAACCGGTGCATTATACGGCGGTGTGTTATATGTTGATTC
ACTTTCAACTAAGGATGGTGCTGTTCCAACTTATTTAGATCTATTAAAAGTCACTATAAGTACAATTGTGGACGGTTTTG
AAAAAAGTAAAAAATAA

Protein sequence : 
MKLSFLKQVFVVALGLSATLAMAAPFKVVTTFTVIQDIAQNVAGDKAVVESITKPGAEIHDYQPTPKDIAKAQKADLILW
NGMNLERWFERFFENVKGKPAVVVTEGITPIAITEGEYKNLPNPHAWMSSANALQYIENIRAALVKYDPKNAESYNQNAK
VYAEKVKEIAEPLRQRLSVIPEAQRWLVTSEGAFSYLAQDYQLKELYLWAINAEEQGSPQQVKKVIDGVKANNIPVVFSE
STVSDKPAKQVAKETGALYGGVLYVDSLSTKDGAVPTYLDLLKVTISTIVDGFEKSKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 3e-92 64
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 2e-92 64
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 2e-92 64
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 2e-92 64
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 2e-92 64

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APP7_0274 YP_001968068.1 iron (chelated) ABC transporter periplasmic- binding protein BAC0439 Protein 7e-97 68
APP7_0274 YP_001968068.1 iron (chelated) ABC transporter periplasmic- binding protein BAC0349 Protein 1e-92 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APP7_0274 YP_001968068.1 iron (chelated) ABC transporter periplasmic- binding protein VFG0525 Protein 9e-93 64