Gene Information

Name : APP7_2098 (APP7_2098)
Accession : YP_001969892.1
Strain : Actinobacillus pleuropneumoniae AP76
Genome accession: NC_010939
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase aldA
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2296700 - 2298181 bp
Length : 1482 bp
Strand : -
Note : -

DNA sequence :
ATGAAAGATCTTAACGTTTTCGATAAAAATTACGGCTTATTAATCAATGGCAAATGGACTCAAGGCAGCGGTAACGATTT
ACTTCCTTCTTACAATCCGGCAAACGGCGAAGTCTTAGCGCATTTTGTCGATGCGACCGATGCGGATGTGGATGCGGCGG
TGAAAGCGGCACAAGAAGCATTTAAATCTTGGCGTAAAACGACAGTAGCGGAACGTGCGGCGATTTTAAATAAAATTGCC
GATGTGATTGATGAAAACAGTGAATTATTTGCATTGCAGGAAACCTTGGACAACGGTAAACCGATTCGTGAAACCAGAGC
GGCGGATATTCCGTTGGCTTCCGATCACTTCCGTTATTTCGCCAGTGCGATTCGTGCCGGCGAAGGCAGCTTAAATCAAA
TCAATCAAGAAGAACTCTCGCTCGTATTACGTGAGCCGATCGGTGTAGTCGGACAAATTATTCCGTGGAACTTCCCGTTC
TTAATGGCGGCGTGGAAAATCGCACCGGCATTGGCGGCAGGTTGTACCGTGGTCATTCACCCTTCCAGCACCACTTCGTT
AAGTCTGTTATCTTTTGCGCAAAAAATTAACCATTTACTCCCGAAAGGCGTATTAAACGTAATTACCGGTAAAGGTTCTA
AATCCGGCGAATATATGTTACATCACAAAGGCTTCAATAAATTAGCCTTCACCGGTTCAACTGAAATCGGTCGCCATATT
GCGATTTCCGCCGCGGAATTACTCATTCCGGCAACCTTAGAATTAGGCGGTAAATCGGCCAATATTTTCTTTGACGATAT
GCCGTTCGACAAAGCGTTGGAAGGTGCGCAAAAAGGTATTCTATTCAACCAAGGGCAAGTATGTTGCGCCGGTTCTCGTA
TCTTCGTACAAGAAGGGATTTACGACAAATTTGTGGCGGCACTAGCCGAAGAATTTAAGAAAGTCAAAGTCGGTTTACCG
TGGGAAGACGATACGCAAATGGGTGCGCAGGTCAATGCGGGGCAGCTCAACACCATTTTAAAATATGTGAAAATCGGTGA
AGAAGAAGGCTGTCGTATTATTACCGGCGGTAGAAAAGTGTTATCCGACAACCTTGCTTGCGGCGAATTCGTCGAACCGA
CCTTAATCGAATCGAAAGATAATAACAGCCGTATCGCTCAAGAAGAAATCTTCGGACCGGTGGCAACCGTGATTAAATTC
AAAACCGAAGAAGACGTTATCCGTATGGCAAACGATTCGGAATACGGCTTAGGCGGCGGTGTTTGGACCAAAGACATCAA
CCGTGCGTTACGTGTTTCACAAGCAATCGAAACCGGTCGTGTTTGGGTAAACTGCTATAATATTTTACCGGCGGGCGCAC
CGTTCGGCGGTTATAAATCTTCCGGTATCGGACGTGAAACCCACCAAATGATGTTGGATGCTTACACCCAAGTGAAAAAT
ATCTACATCAGTACCCGTGAAGAACGTGAAGGAATGTATTAA

Protein sequence :
MKDLNVFDKNYGLLINGKWTQGSGNDLLPSYNPANGEVLAHFVDATDADVDAAVKAAQEAFKSWRKTTVAERAAILNKIA
DVIDENSELFALQETLDNGKPIRETRAADIPLASDHFRYFASAIRAGEGSLNQINQEELSLVLREPIGVVGQIIPWNFPF
LMAAWKIAPALAAGCTVVIHPSSTTSLSLLSFAQKINHLLPKGVLNVITGKGSKSGEYMLHHKGFNKLAFTGSTEIGRHI
AISAAELLIPATLELGGKSANIFFDDMPFDKALEGAQKGILFNQGQVCCAGSRIFVQEGIYDKFVAALAEEFKKVKVGLP
WEDDTQMGAQVNAGQLNTILKYVKIGEEEGCRIITGGRKVLSDNLACGEFVEPTLIESKDNNSRIAQEEIFGPVATVIKF
KTEEDVIRMANDSEYGLGGGVWTKDINRALRVSQAIETGRVWVNCYNILPAGAPFGGYKSSGIGRETHQMMLDAYTQVKN
IYISTREEREGMY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-97 52
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-100 50
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-100 50
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-100 50
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-100 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APP7_2098 YP_001969892.1 aldehyde dehydrogenase aldA VFG0082 Protein 4e-98 52