Gene Information

Name : APP7_1756 (APP7_1756)
Accession : YP_001969550.1
Strain : Actinobacillus pleuropneumoniae AP76
Genome accession: NC_010939
Putative virulence/resistance : Virulence
Product : capsule polysaccharide modification protein LipA
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 1951261 - 1953330 bp
Length : 2070 bp
Strand : +
Note : -

DNA sequence : 
GTGGCGCAATGTTCTATCACTAAATCGTTAATTTTCTCACGCGGAATTTTAAAGATCCCTCATTTAAATGCTTTCTTACA
TGATAGTGAGTTAATCTCTTATTCTCGTTTGACCAAAACGATTCGAGCGGATAATGTCATCGGTTGGGGATTACGCCCTT
CTGCGGACAAAGCTCGTGCTTATGCCGAACAACATTATCTTCCTTATATTGCATTAGAAGACGGTTTTTTACGTTCGCTC
GGGCTGGGTGTTATGGGATACCCGCCTTTCTCCGTTGTGTATGATGATGTCGGTATTTATTACGACACGACACGTTCATC
CCGCTTAGAGCAGCTGATTCTCAGTTCGCATTTTAGCGCAACCGATCTTCAACAGGCGGAGCAAGCCGTGCGGCTAATTG
TTCGTCATCAGTTATCAAAATATAACCATAATCTTGATTATGTTTCCAATGAACCGAAAACAAGTGAAATCGTATTAGTC
ATAGATCAAACCTTTGGTGATATGGCGGTAAAATACGGTCGGGCGAATGAATCCGATTTCCAACAAATGCTGGATGCGGC
GATTGGTGAAAATCCCGATGCTCAAATTTGGGTAAAAACGCATCCGGATGTAATTAGCGGAAAGAAAAAAGGTTATTTAA
CCGATTTACATCGTTACGGTAACCGAATTCGTTTATTCGCGGAAGACGTTAATCCTATCTCCCTGTTGAGTCGGGTTGAT
AAAGTGTATTGTGTCACTTCACAGATGGGGTTTGAGGCACTGTTATTAGGAAAAAAAGTCGTTACGTTTGGTATTCCTTG
GTTTGCCGGTTGGGGTATTACGGACGATAGACATCCGGATATAGATATTTTAAAACTTGAGCAGCGTCGGAAAAACCGTT
CTTTTATTCAATTATTTGCGGCAGCCTATCTGCAATATAGCCGTTATATTAATCCGTATTCGGGAAAAGTCGGTACGATT
TTTGATGTTATCGATTATCTGAGCAAAGTGAAAATATTGAATCAACGATTAAGCGGTCATCTTTATTGTGTCGGTATGTC
GTTGTGGAAACGAGCCGTGATTAAGCCGTTTTTTAACTTGCCTTTATGCCGATTACATTTTGTCGGCTCATTAAAATCGT
TAGAAAAACGCGTTTTTGAGAAGAATGCGAGATTACTTCTTTGGAGCCAAGGTAAACCGGAAATTCTCGCGTTTGCCGAA
AAACATAATTTACCGCTTTTACGTATGGAAGACGGGTTTATTCGCTCCGTAGGACTCGGTTCTAATTTAGTTGCACCGTT
ATCATTGGTGATTGATGATTTAGGTATTTATTTTAATGCACAAACGCCTTCTCGTTTAGAAGAGATTTTATTGCATCAAG
AATTTAGTGAGCAGGATTTAGTCCTAGCGAAAAAATTACAAACTCGCTTATTAGAAGCAAATATCGGCAAATATAATGTG
GGAAGTGCCGGCTTCCAACTTAATGTCACGGATAAACGTACCATTTTAGTACCCGGTCAGGTGGAAGATGACGCTTCTAT
TCGTTTCGGTTCTCCGGAAATTAAGAAAAATTTGGATTTGTTGCGTAAGGTTAGAGAATTAAATCCTAATGCTTACATTA
TTTATAAACCGCATCCGGATGTAGTTAGCGGTAATCGACAAGGGCATATACCGACCGAACAAGCGGTCGAATTTGCCGAT
GAAATTGTCGAAAACGCCAATATCTTAGACTGCATCAACCAAGTTGATGAAGTACATACGATGACCTCATTAGCCGGTTT
CGAAGCTCTATTACGTGGGAAAATCGTGCATTGTTACGGACTGCCTTTTTATTCGAATTGGGGATTAACCGAAGATTATC
TTTCGCTTGAACGTCGTCACAGAAAGTTATGTTTGGAAGAACTTATTTCGGCGGTACTGGTATATTATCCTCAATATGTC
GATCCGGAAAATGCGACAATGATTAATGCGGAACAAGCGATTGAAATTCTGCAACAACAAAAACAACAGCTATCACATAG
CGGTATTAAACGTCCGTGGATCGCCAAACAGTTTGGTAAATTGAAACAGCTTTATCGCACATTGCAATAA

Protein sequence : 
MAQCSITKSLIFSRGILKIPHLNAFLHDSELISYSRLTKTIRADNVIGWGLRPSADKARAYAEQHYLPYIALEDGFLRSL
GLGVMGYPPFSVVYDDVGIYYDTTRSSRLEQLILSSHFSATDLQQAEQAVRLIVRHQLSKYNHNLDYVSNEPKTSEIVLV
IDQTFGDMAVKYGRANESDFQQMLDAAIGENPDAQIWVKTHPDVISGKKKGYLTDLHRYGNRIRLFAEDVNPISLLSRVD
KVYCVTSQMGFEALLLGKKVVTFGIPWFAGWGITDDRHPDIDILKLEQRRKNRSFIQLFAAAYLQYSRYINPYSGKVGTI
FDVIDYLSKVKILNQRLSGHLYCVGMSLWKRAVIKPFFNLPLCRLHFVGSLKSLEKRVFEKNARLLLWSQGKPEILAFAE
KHNLPLLRMEDGFIRSVGLGSNLVAPLSLVIDDLGIYFNAQTPSRLEEILLHQEFSEQDLVLAKKLQTRLLEANIGKYNV
GSAGFQLNVTDKRTILVPGQVEDDASIRFGSPEIKKNLDLLRKVRELNPNAYIIYKPHPDVVSGNRQGHIPTEQAVEFAD
EIVENANILDCINQVDEVHTMTSLAGFEALLRGKIVHCYGLPFYSNWGLTEDYLSLERRHRKLCLEELISAVLVYYPQYV
DPENATMINAEQAIEILQQQKQQLSHSGIKRPWIAKQFGKLKQLYRTLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 0.0 61
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 3e-141 51
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 3e-141 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APP7_1756 YP_001969550.1 capsule polysaccharide modification protein LipA VFG0704 Protein 0.0 64
APP7_1756 YP_001969550.1 capsule polysaccharide modification protein LipA VFG0692 Protein 0.0 63
APP7_1756 YP_001969550.1 capsule polysaccharide modification protein LipA VFG0259 Protein 0.0 61