Gene Information

Name : APP7_1678 (APP7_1678)
Accession : YP_001969472.1
Strain : Actinobacillus pleuropneumoniae AP76
Genome accession: NC_010939
Putative virulence/resistance : Virulence
Product : urease subunit alpha UreC
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1867973 - 1869691 bp
Length : 1719 bp
Strand : -
Note : -

DNA sequence :
ATGGCATTAACAATCCCACGCAGTCAGTATGTAGCGACTTACGGCCCGACAGTCGGTGATAAAGTCCGTTTAGGCGACAC
CGATTTATGGGCGACAATTGAACAAGATTTTTTAACCAAAGGCGATGAGTGTAAATTCGGCGGCGGTAAATCGGTGCGTG
ACGGTATGGCACAATCAAGCACCGCTACCCGTGATAATCCGAACGTATTGGATTTTGCCCTCACTAATGTGATGATTATC
GACGCAAAATTAGGCATTATCAAAGCGGATATCGGGATTCGTGACGGACGCATTGTCGGTATCGGTCAGGCGGGTAATCC
GGATACGATGGATAACGTTACGCCAAATATGATTATCGGCGCAAGCACCGAAGTACATAACGGCGCACATTTAATTGCGA
CCGCCGGCGGTATCGATACTCACATTCACTGGATCTGCCCGCAACAGGCACAACACGCTATCGAAAACGGCATTACTACG
ATGATCGGCGGTGGTTCAGGCCCGGCGGACGGCACGCATGCCACCACCTGTACACCGGGTAAATTTAATATCGAAAGAAT
GTTCCAAGCTTGCGAAGCGTTACCGGTCAATATCGGCTTTTTCGGCAAAGGTAACTGTTCTATGCTCGAACCGCTTAAAG
AACAAGTGGTTGCCGGTGCGTTAGGCTTAAAAATCCACGAAGACTGGGGGGCAACACCGGCAGTGATTGACGCAGCGTTA
AAAGTAGCGGACGAAATGGATGTGCAAGTAGCGATTCACACCGATACGCTCAACGAAAGTGGTTTCTTAGAAGACACGAT
GAAAGCGATTAACGGACGTGTGATTCACACTTTCCACACCGAAGGTGCCGGCGGCGGTCATGCACCGGATATTATTAAAG
CGGCGATGTACCCGAACGTATTGCCGGCTTCAACCAATCCGACCCGTCCGTTTACCGTGAACACGATTGACGAGCATTTG
GATATGCTAATGGTTTGTCACCACTTAGATAAACGAGTGCCGGAAGATGTGGCATTTGCGGATAGCCGTATCCGTCCCGA
AACCATTGCGGCGGAAGACATTCTGCACGATATGGGCGTGTTCTCGATTATGAGTTCAGATTCTCAAGCAATGGGACGTG
TCGGCGAAGTAGTGACTCGTACGTGGCAAACGGCAGATAAAATGAAAGCGCAGCGTGGCGCATTGGGCGATGAAGGTAAC
GACAACTTCCGTATTAAACGCTATATTGCGAAATACACGATTAATCCGGCAATTGCTCACGGTATCAGCCAATACGTCGG
CTCGCTTGAAGTGGGTAAACTAGCCGACATCGTATTGTGGAAGCCGCAATTCTTCGGCGTAAAACCGGAATTTGTGATGA
AAAAAGGCTTTATCAGCTTTGCTAAAATGGGTGACCCGAACGCTTCAATCCCAACGCCACAACCGGTATTCTACCGCCCA
ATGTTTGGGGCGAATGCGAAAGCGAATACCGAAAGTGCGGTTTATTTCGTTTCACAAGCGAGCGTGGATGCGAACATCAA
AGCCCAATACGGCATTCAGAAAGAAACCCTCGCGGTAAAAGGTTGTCGTGATGTAGGTAAAAAAGACCTCGTTCACAACA
ATGCAACGCCTGAAATTACCGTAGATCCGGAACGCTACGAAGTACGTGTGGACGGCGAGCATATTACTTGCGAACCTGCT
ACCAAAGTGCCACTTGCACAGCGTTATTTCTTGTTCTAG

Protein sequence :
MALTIPRSQYVATYGPTVGDKVRLGDTDLWATIEQDFLTKGDECKFGGGKSVRDGMAQSSTATRDNPNVLDFALTNVMII
DAKLGIIKADIGIRDGRIVGIGQAGNPDTMDNVTPNMIIGASTEVHNGAHLIATAGGIDTHIHWICPQQAQHAIENGITT
MIGGGSGPADGTHATTCTPGKFNIERMFQACEALPVNIGFFGKGNCSMLEPLKEQVVAGALGLKIHEDWGATPAVIDAAL
KVADEMDVQVAIHTDTLNESGFLEDTMKAINGRVIHTFHTEGAGGGHAPDIIKAAMYPNVLPASTNPTRPFTVNTIDEHL
DMLMVCHHLDKRVPEDVAFADSRIRPETIAAEDILHDMGVFSIMSSDSQAMGRVGEVVTRTWQTADKMKAQRGALGDEGN
DNFRIKRYIAKYTINPAIAHGISQYVGSLEVGKLADIVLWKPQFFGVKPEFVMKKGFISFAKMGDPNASIPTPQPVFYRP
MFGANAKANTESAVYFVSQASVDANIKAQYGIQKETLAVKGCRDVGKKDLVHNNATPEITVDPERYEVRVDGEHITCEPA
TKVPLAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 6e-169 64
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 6e-169 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-148 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-148 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-148 60
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-148 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APP7_1678 YP_001969472.1 urease subunit alpha UreC VFG0270 Protein 7e-163 63