Gene Information

Name : APP7_1145 (APP7_1145)
Accession : YP_001968939.1
Strain : Actinobacillus pleuropneumoniae AP76
Genome accession: NC_010939
Putative virulence/resistance : Virulence
Product : chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1291023 - 1293368 bp
Length : 2346 bp
Strand : +
Note : -

DNA sequence :
ATGAATTTCGAAAAATTTACTACCAAATTGCAAGAAGCCCTTGCAGAAGCCCAATCGTTAGCTATCGGAAAAGATAATAA
CTACATTGAACCGGCACATTTACTTTATGCGTTAGTCAAACAACCGGACGGCTCTATCGCCCCGCTATTTACCGCACTCA
ATGTGCAACCGCAACGCATATTGAGTGAATTGGAAGCGATTTTAAACCGCTTACCGACCGTATCCGGCGGTACGACACAG
CCGTCACAGCAACTGATTCGCCTGTTAAATCAATGTGATAAATTGGCGCAACAATTCGGCGACAGCTTTATTTCATCGGA
GTTATTCGTGCTTGCCGCACTGGACGATAACGGCGATTTAGGTAAATTATTAAAACAATTTGGCTTGACTAAAGAAAAAG
TAAACGCAGCCATCAGCCAAATTCGAGGAGGAGAAAACGTGAATAATCAAAACGCAGAAGAAACTAGACAAGCCCTTCAA
AAATATACTATCGATCTTACCGAAAGAGCCAAAGCCGGTAAATTAGATCCGGTCATCGGGCGTGATGAAGAAATCCGCCG
TGCAGTACAAGTTTTACAACGCCGTACTAAAAATAACCCGGTATTAATCGGTGAACCTGGGGTCGGTAAAACTGCGATCG
TAGAAGGCTTGGCACAACGTATCGTCAACGGCGAAGTGCCGGAAGGTTTAAAAAATAAACGTGTACTTTCTCTCGATATG
GGCGCATTAATTGCTGGTGCAAAATATCGCGGCGAATTTGAAGAACGTCTAAAAGCGGTACTTAACGAATTAGCCAAAGA
AGAAGGTCAGGTTATCTTATTTATTGATGAAATTCACACCATGGTCGGTGCGGGTAAAACAGACGGCGCAATGGATGCCG
GTAACTTACTCAAGCCGTCACTTGCTCGCGGCGAATTACATTGCGTTGGGGCAACTACGTTAGACGAATACCGCCAATAT
ATCGAAAAAGATGCGGCACTTGAACGTCGTTTCCAAAAAGTATTAGTGGACGAACCGACCGTTGAGGATACGATTGCAAT
TTTACGCGGCTTGAAAGAACGTTATGAAATTCATCACCACGTACAAATTACCGACCCGGCAATTGTCGCGGCGGCAACGC
TTTCGCACCGTTATATTTCCGACCGCCAATTACCGGATAAAGCGATCGATTTAATTGATGAAGCCGCATCCAGTTTACGT
ATGGAAATCGATTCTAAACCTGAGCCGTTGGATAAACTTGAACGCCGTATTATTCAACTTAAATTGGAACGCCAAGCGTT
ACAAAAAGAGGAAGATGAAGCAAGCCGCCAACGTCTTGCAAAATTAGATGAAGAATTGACCGCTCGCGAGCGTGAATATT
CCGAATTGGAAGAAGTTTGGAAAGCGGAGAAATCAGCATTACTCGGTACGCAACATATCAAAACTGAGTTAGAAAATGCC
CGTATCGAAATGGATCAGGCTCGCCGTGAAAATAATTTCGAGAAAATGTCCGAATTGCAATACGGTAAAATTCCGGCATT
GGAAAAACAACTTGCAGAAGCGGTAAAACGTGAGGAAGAAGGTGGTGAAAATCAGCTACTTCGTACCAAAGTGACCGATG
AAGAAATTGCGGAAGTGCTTTCGAAAGCGACAGGTATTCCGGTGTCTAAAATGATGGAAGGCGAAAAAGAAAAACTGTTG
CGTATGGAAGAGGTATTACACAGCCGTGTTATCGGGCAGAATGAAGCGGTTGAAGCGGTAGCAAATGCGATTCGCCGTAG
CCGTGCCGGATTGTCGGATCCGAATCGCCCGATTGGTTCGTTCTTATTCCTCGGCCCGACTGGGGTCGGTAAAACCGAAC
TTTGCAAAACCTTGGCGAATTTCCTATTCGATGATCCGGATGCGATGGTACGTATCGATATGTCGGAATTTATGGAAAAA
CACAGCGTTTCTCGTTTAGTCGGCGCACCTCCGGGCTATGTCGGTTACGAAGAAGGCGGTTACTTAACCGAAGCGGTTCG
CCGCCGTCCGTATTCTGTAGTGTTACTCGATGAAGTGGAAAAAGCACACCCTGATGTGTTTAATATCTTGCTTCAAGTGT
TGGATGACGGTCGTTTAACTGACGGACAAGGTCGTACGGTGGATTTCCGCAATACAGTAGTGATTATGACCTCAAACTTA
GGCTCGCATTTAATCCAAGAAAATCCGGAATTGGATTACGCCGGAATGAAAGAAGTAGTAATGTCAGTGGTAGGACAACA
TTTCCGTCCTGAATTTATCAACCGTATTGATGAAACCGTAGTGTTCCACCCCACTTTGGTCAAGAGCATATTCGTGCAAT
TGCTCGTATTCAGTTACAACGTTTAA

Protein sequence :
MNFEKFTTKLQEALAEAQSLAIGKDNNYIEPAHLLYALVKQPDGSIAPLFTALNVQPQRILSELEAILNRLPTVSGGTTQ
PSQQLIRLLNQCDKLAQQFGDSFISSELFVLAALDDNGDLGKLLKQFGLTKEKVNAAISQIRGGENVNNQNAEETRQALQ
KYTIDLTERAKAGKLDPVIGRDEEIRRAVQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLDM
GALIAGAKYRGEFEERLKAVLNELAKEEGQVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYRQY
IEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASSLR
MEIDSKPEPLDKLERRIIQLKLERQALQKEEDEASRQRLAKLDEELTAREREYSELEEVWKAEKSALLGTQHIKTELENA
RIEMDQARRENNFEKMSELQYGKIPALEKQLAEAVKREEEGGENQLLRTKVTDEEIAEVLSKATGIPVSKMMEGEKEKLL
RMEEVLHSRVIGQNEAVEAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDDPDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSHLIQENPELDYAGMKEVVMSVVGQHFRPEFINRIDETVVFHPTLVKSIFVQLLVFSYNV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 9e-101 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 7e-101 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APP7_1145 YP_001968939.1 chaperone ClpB VFG0079 Protein 1e-119 42
APP7_1145 YP_001968939.1 chaperone ClpB VFG2084 Protein 3e-107 42