Gene Information

Name : APP7_1009 (APP7_1009)
Accession : YP_001968803.1
Strain : Actinobacillus pleuropneumoniae AP76
Genome accession: NC_010939
Putative virulence/resistance : Virulence
Product : RTX-I toxin-activating lysine-acyltransferase ApxIC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2994
EC number : 2.3.1.-
Position : 1126087 - 1126569 bp
Length : 483 bp
Strand : -
Note : -

DNA sequence : 
ATGATGCTAAAAAATGATTTTAACGTATTGGGACAAATTGCTTGGTTATGGGCAAATTCTCCAATGCACCGAAATTGGTC
AGTTTCACTGTTAATGAAGAATGTTATTCCTGCAATTGAAAATGACCAATATTTGTTACTAGTTGATGATGGTTTTCCTA
TTGCATATTGCAGTTGGGCCAAATTAACTCTAGAGAGTGAGGCTCGCTATGTAAAGGACACCAATTCATTAAAAATAGAT
GATTGGAATGCAGGAGATCGTATATGGATCATTGATTGGATTGCCCCATTCGGGGATTCATCTCTATTGTATAAACATAT
GAGACAACGTTTTCCATACGATATTGGAAGGGCAATTAGAATCTATCCTAGCAAAAAAGATACTGGAAAAATCATATATT
TAAAAGGAGGAAAAATAACAAAAAAAGTAGCTGAAAAGACATTTCTTCAGTATGAGCAAGAGTTAATAACAGCTCTACAA
TAA

Protein sequence : 
MMLKNDFNVLGQIAWLWANSPMHRNWSVSLLMKNVIPAIENDQYLLLVDDGFPIAYCSWAKLTLESEARYVKDTNSLKID
DWNAGDRIWIIDWIAPFGDSSLLYKHMRQRFPYDIGRAIRIYPSKKDTGKIIYLKGGKITKKVAEKTFLQYEQELITALQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyC CAD42040.1 HlyC protein Virulence PAI II 536 Protein 1e-42 55
hlyC CAD33758.1 hemolysin C Virulence PAI I 536 Protein 5e-42 55
hlyC NP_755444.1 hemolysin C Virulence PAI I CFT073 Protein 6e-42 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APP7_1009 YP_001968803.1 RTX-I toxin-activating lysine-acyltransferase ApxIC VFG1559 Protein 4e-43 55
APP7_1009 YP_001968803.1 RTX-I toxin-activating lysine-acyltransferase ApxIC VFG1499 Protein 2e-42 55
APP7_1009 YP_001968803.1 RTX-I toxin-activating lysine-acyltransferase ApxIC VFG0905 Protein 2e-42 54
APP7_1009 YP_001968803.1 RTX-I toxin-activating lysine-acyltransferase ApxIC VFG0842 Protein 7e-40 51
APP7_1009 YP_001968803.1 RTX-I toxin-activating lysine-acyltransferase ApxIC VFG0158 Protein 1e-29 43