Gene Information

Name : folP (LBF_3127)
Accession : YP_001964174.1
Strain :
Genome accession: NC_010842
Putative virulence/resistance : Resistance
Product : dihydropteroate synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0294
EC number : -
Position : 3361688 - 3362503 bp
Length : 816 bp
Strand : +
Note : cytoplasmic protein

DNA sequence :
ATGGCTGAAATCTTCGGAATCTTAAACATCACCACTGACTCCTTTAGTGATGGAGGTAAGTACATAAACCCCGATGACGC
TATCAAAAAAGGAGTCCAACTCTTACAAGAAGGGGCTGATTGGTTGGATGTCTCAGGCCAATCTTCCAATATTGCGGCAA
ACCTCGTCACAGAGGAGGAAGAATGGAAACGTGTGGAACCTGTCATCCGTTACTTTGTTCCGAAAGGGGTTCGAATCAGT
TTGGATAGTTTCCGACCCAATGTACAAAAGAAAGCAATTGAGGCTGGGGTTCGTTGTTTGAATGACATCACTGGATTTAC
CTACGAAGGGGATCGTGAGTTTTTAAAAACTTACGGTGCAAAGCACTCTGATCTAAAATTCATCATCATGCATTCGCATA
ACAGAAATATTGCGAAAATGAAATCAACTTTGTCTCCAGAAAAAGTAATCAAAAAAATCCAGATCTTTTTTAGAGACAGA
AGAAATGATCTAACTGCGATGGGAATTTCAGAATCATCTATCTTTTTTGATCCAGGGATGGGTTTTTTCTTGAGTGATGA
CCCTATGGTTTCCTTTCGAGTGCTTCAAGATCTAGAAATCCTAAAATTGGAATTTCCACAACTGATGGTGAGTGTCTCTC
GAAAATCATTTCTCGGAAATGTTTTGGGAAATTTACCAATTGAAGATCGGGAATTTGCAACTCTCGCATGTGAATTACAT
TTATTAAAAAATAAAATCCCTTTCATTCGGACGCATAACGTCCTTAAGCTGAGACATGCCGAAAAAATTTGGAATTTATG
CCAAGAGAGTGAATGA

Protein sequence :
MAEIFGILNITTDSFSDGGKYINPDDAIKKGVQLLQEGADWLDVSGQSSNIAANLVTEEEEWKRVEPVIRYFVPKGVRIS
LDSFRPNVQKKAIEAGVRCLNDITGFTYEGDREFLKTYGAKHSDLKFIIMHSHNRNIAKMKSTLSPEKVIKKIQIFFRDR
RNDLTAMGISESSIFFDPGMGFFLSDDPMVSFRVLQDLEILKLEFPQLMVSVSRKSFLGNVLGNLPIEDREFATLACELH
LLKNKIPFIRTHNVLKLRHAEKIWNLCQESE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sul2 AEZ06044.1 Sul2, sulphonamide-insensitive dihydropteroate synthase Not tested Tn6167 Protein 6e-32 41
sul2 AEA34678.1 dihydropteroate synthase Not tested Not named Protein 5e-32 41
sulI2 AFV47959.1 sulphonamide-insensitive dihydropteroate synthase SulI2 Not tested AbaR25 Protein 5e-32 41
ABK1_0255 YP_005512827.1 Dihydropteroate synthase type-2 Not tested AbaR4d Protein 8e-32 41
BJAB07104_00246 YP_008207711.1 Dihydropteroate synthase-related enzyme Not tested AbaR25 Protein 8e-32 41
BJAB0868_00253 YP_008211579.1 Dihydropteroate synthase-related enzyme Not tested AbaR26 Protein 8e-32 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
folP YP_001964174.1 dihydropteroate synthase AJ459418.gene.p01 Protein 4e-39 42
folP YP_001964174.1 dihydropteroate synthase DQ464881.1.gene2.p01 Protein 1e-31 42