Gene Information

Name : leuS (LBF_0255)
Accession : YP_001961378.1
Strain :
Genome accession: NC_010842
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 259530 - 262133 bp
Length : 2604 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAATTATCCATTCCAAGATATTGAACAAAAATGGCAAAAATACTGGGACCACCACCAGACCTTTCGCACAAACACACA
CTCATCCAAACCTAAATACTATTGTTTAGACATGTTTCCTTACCCAAGTGGTGCCGGCCTTCACGTAGGCCACCCAGAAG
GATACACTGCCACTGACATCATCTCAAGACTCAAACGTATGGAAGGATACGAGGTTTTGCACCCGATGGGTTGGGACGCC
TTTGGTCTCCCTGCAGAACGTTATGCCATGACAACGGGCATCCACCCTCGTACCACCACGAAAAACAACATCGATACCTT
CCGTCGCCAAATCAAAAGCCTTGGGCTTTCGTACGATTGGGAAAGGGAAATTTCGACCACTCACCCAGACTATTACCGCT
GGACCCAGTGGATTTTTTTACAAATCTACAATTCCTACTTTGACAGAAAACAAAACAAGGCAGTTCCTATCACCACTCTG
ATCCAAACCTTGGAAAGAGAAGGATCTTTGTTTTTTGAAGGCGTTGAACTACCGAAAGGAATTCAATTCACCGCTTCCGA
ATGGAAGTCCAAGTCTCGGAAAGAAAAAGAGGACATTTTGTCCCATTTCCGATTGGTGTACGAAGCCAATATCCCGGTGA
ATTGGTGTGAAGCGCTCGGAACCGTTCTTGCCAACGAAGAAGTGGAAGAATGGACCTCCAAAGGGTATTCTGTCGAACGA
AAACCAATGCGCCAGTACATGATGCGCATCACAGCTTATGCCGAACGACTCTTAAATGATCTTTCTCTCTGTGAATGGCC
TCCCTCCACTCTGGAGATGCAACGCAATTGGATTGGGAAATCAGAAGGATTGGAACTCAGTTTCCATGTTCCTTCCTTAA
ACAAAGACATCACCGTTTACACCACTCGGCCTGATACCATTTTTGGTGCCACTTACCTCGTCCTTGCCCCAGAACACGCA
CTTGTCGCAGAACTCACCACGCCTGAACAAACAGAAGCGGTCGGGCAATACCAAAAAGATTGTTCTTTAAAAAGTGATTT
GGAACGAACTGAACTGAATAAAGACAAAACGGGAGTGTTTACTGGAGCTTATGCCCAGTTGCCAACAGACCCATCTGTCA
AAGTACCGATTTATATTTCTGATTATGTATTAATCTCGTATGGAACGGGTGCCATTATGGCGGTTCCAGCGCACGACCAA
AGAGACTATGATTTTGCAGTCAAATTTAATCTCCCCATCAAACAAGTGATTGATGGAAAGATGGAAACAAATTTAGCCTT
TGATTCCAAAGACTCGGTTTGTATCAACTCATCCTCCGCAGAAGTACAGTTAGATGGCAAATCTTACAAAGACGCCTTCC
AAACCATGGTGGTTTGGGCAGAAAAAAAAGGGATTGGTCGCAAAAAAATCCAATTCAAACTCAGAGATTGGTTATTTGCC
AGACAAAGGTATTGGGGAGAACCCATCCCACTCGTTCACTTTGAAGATGGATCCCCAAAAGCCTTATCTGATTCTGAACT
GCCATTAGTTCTTCCTGACCTAGAAGAATTCAAACCATCCGGAACAGGGGAATCTCCACTTGCTCTCGCCAAAGACTGGT
TAGTTTACAAAGACCCAGAAACAGGAGAAATTGGCAAAAGAGAAACCAATACCATGCCACAGTGGGCTGGGTCTTGTTAT
TATTACCTTCGTTACATTGATCCAAGAAACAATGATAAACTCATTGATCCAGAACTCGAAAAGATGTGGATGCCAGTAGA
AGTTTATGTGGGTGGAGCAGAACATGCCGTATTACATCTGTTATACTCTCGATTTTGGCATAAAATCCTTTTTGATTTGG
GCCATGTCTCCACTCCAGAACCATTCAAAAAATTAGTCCACCAGGGCCTCATTCTGGGAGAAGACAAAGGCAAAATGTCC
AAGTCTCGTGGCAATGTTGTCAATCCAGATGACGTTGTTTCTGAATTTGGTGCCGACACACTACGTCTCTTTGAAATGTT
TATGGGTCCGTTTGAAATGTCCAAACCTTGGAGTAAAAACGGAGTCGATGGAGTCTTCCGATTTTTAAATCGTGTTTGGC
GACTCTTTCATTCAGGCGAAAACGAATCCTTTTTTGTGGAAGACATCGAACCGAATGAAGCGGAACAGAAAACCCTCCAT
AGGACAATCAAAAAAGTAAAAGACGATATTGATAGTTTCTCTTTCAATACAGCGGTTTCTCAAATGATGATCTTCATCAA
TGAGTTCACAAGTAATCCTAGAAAACCAAAACAAGTATTGGAACCCTTTGTTTTAGCTCTTAGCCCGTTTGCACCTCACC
TAGCAGAAGAACTGTGGGCAAAACTAGGACACACAGATTCTCTCGCTTACCATCCCTACCCAAAATGGGATGAGAAATAT
TTAATTGATGCCAATATCACCATCGTTGTCCAAGTGAATGGCAAGATGCGTGGGGAATTTTTAGCACCGAGAGAGATCGA
AGAAAAAGAAGCTTTGTCACTTGCCAAAGAAGTAGAAAAGGCAAAACCTTTCTGGGTCGGAAAAGAAATCAAAAAAGAAA
TTTATGTCAAAGGCAAACTCGTCAATATCGTTGTGGCGGGTTAA

Protein sequence :
MNYPFQDIEQKWQKYWDHHQTFRTNTHSSKPKYYCLDMFPYPSGAGLHVGHPEGYTATDIISRLKRMEGYEVLHPMGWDA
FGLPAERYAMTTGIHPRTTTKNNIDTFRRQIKSLGLSYDWEREISTTHPDYYRWTQWIFLQIYNSYFDRKQNKAVPITTL
IQTLEREGSLFFEGVELPKGIQFTASEWKSKSRKEKEDILSHFRLVYEANIPVNWCEALGTVLANEEVEEWTSKGYSVER
KPMRQYMMRITAYAERLLNDLSLCEWPPSTLEMQRNWIGKSEGLELSFHVPSLNKDITVYTTRPDTIFGATYLVLAPEHA
LVAELTTPEQTEAVGQYQKDCSLKSDLERTELNKDKTGVFTGAYAQLPTDPSVKVPIYISDYVLISYGTGAIMAVPAHDQ
RDYDFAVKFNLPIKQVIDGKMETNLAFDSKDSVCINSSSAEVQLDGKSYKDAFQTMVVWAEKKGIGRKKIQFKLRDWLFA
RQRYWGEPIPLVHFEDGSPKALSDSELPLVLPDLEEFKPSGTGESPLALAKDWLVYKDPETGEIGKRETNTMPQWAGSCY
YYLRYIDPRNNDKLIDPELEKMWMPVEVYVGGAEHAVLHLLYSRFWHKILFDLGHVSTPEPFKKLVHQGLILGEDKGKMS
KSRGNVVNPDDVVSEFGADTLRLFEMFMGPFEMSKPWSKNGVDGVFRFLNRVWRLFHSGENESFFVEDIEPNEAEQKTLH
RTIKKVKDDIDSFSFNTAVSQMMIFINEFTSNPRKPKQVLEPFVLALSPFAPHLAEELWAKLGHTDSLAYHPYPKWDEKY
LIDANITIVVQVNGKMRGEFLAPREIEEKEALSLAKEVEKAKPFWVGKEIKKEIYVKGKLVNIVVAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-159 51