Gene Information

Name : guaA (Cphamn1_0342)
Accession : YP_001958791.1
Strain : Chlorobium phaeobacteroides BS1
Genome accession: NC_010831
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 351647 - 353191 bp
Length : 1545 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCATTCAGTTCTGGTTCTTGATTTCGGCTCGCAATACACCCAGCTTATCGCACGACGTATTCGAGAGATCGGCATCTA
TTCGGAAATCGTCCCGTACAACACCCCGCTGGAAAAAATCCGGGAACACAATCCGGGGGCGATCATTCTCTCAGGAGGCC
CCAGCAGCGTCTATGGAGAGTCCGCGTTTCACCCGGATGAGGGAATTTTCAAACTCGGCGTCCCCATCCTCGGCATCTGT
TATGGCCTTCAGGTCATAGCAACTCATTTCGGCGGTTCTGTAGACTCTTCGGCAAAACAGGAGTTCGGAAGAGCAGAAAT
TCAGGTCGAACGTCATGACGGAAATCCTCAAAGCATGCTCTTCAAGGATATTCCCGATTCACATGTCTGGATGAGCCACG
GGGACAAGGTAGTCAGAATGCCGGAAGGATTCCGAGTTACCGCAAGCAGCGGCAACTCGGAAATGTGCGCGATTGAAGCC
TCAGGCGACAAAGCGGCGCTCAAAGTGTTCGGCCTGCAGTTTCACCCTGAAGTACAGCATACCCTGTATGGAAAACAGCT
GCTTTCAAATTTCCTGCTGGACATTGCCGGCCTGACGCCTGACTGGTCACCGAAAAGCTTTATCGAACACCAGATCGAGG
AGATCCGCACTACGGTCGGCAAGAATACAGTTATTTGCGGCATAAGCGGCGGCGTTGACTCTACGGTCGCCGCCGTGCTT
GTCAGCAAGGCTATCGGCAAACAGCTTCATTGTGTGTTCGTCGATAACGGGCTCTTGAGGAAGCATGAAGGGGACAAGGT
CATGAAAATCCTCAAACCTCTCGGACTGAGCGTCAATCTGGTAGACGCCGAAGAGATATTCCTCAAACGGTTAAAAAGCA
TCGCTTCACCGGAAAAAAAGCGGAAAATTATCGGCAGGACCTTTATTCATATTTTCGAGGAGCAGATTCACGAAGAGAAA
TTCCTCGTTCAGGGAACACTCTATCCCGATGTCATTGAAAGTGTCAGCGTCAAAGGACCATCTGAAACCATCAAGTCGCA
CCATAACGTCGGCGGCCTTCCTAAAAGGATGAAGCTCAAACTCATTGAACCCCTGCGCGAACTGTTCAAGGACGAGGTAC
GTGCTGTCGGACGTGAACTCGGCATCGATGAAGACATCCTCATGCGCCACCCGTTTCCCGGACCCGGCCTCGCCGTGCGC
GTTCTCGGGTCGGTCAGCAAAACCCGCCTCGATATCCTGCGGGATGCCGATGAGATCTTCCTTGAAGAACTCAAATCACA
GAACCTCTACCATCATGTATGGCAGGCGTTCTCCGTTCTGCTTCCCGTGCAGTCTGTCGGCGTCATGGGTGACAAACGCA
CCTATGAAAATGTCCTCGCTCTCCGCGCCGTTGAATCCTCTGACGGCATGACCGCGGACTGGGCCCATCTGCCGCACGAG
TTTCTTTCGAGGGTTTCCAATCGCATCATCAACGAGGTCCGGGGCATCAACAGGGTCGCCTACGACATCTCCTCCAAACC
GCCGGCAACCATAGAATGGGAGTGA

Protein sequence :
MHSVLVLDFGSQYTQLIARRIREIGIYSEIVPYNTPLEKIREHNPGAIILSGGPSSVYGESAFHPDEGIFKLGVPILGIC
YGLQVIATHFGGSVDSSAKQEFGRAEIQVERHDGNPQSMLFKDIPDSHVWMSHGDKVVRMPEGFRVTASSGNSEMCAIEA
SGDKAALKVFGLQFHPEVQHTLYGKQLLSNFLLDIAGLTPDWSPKSFIEHQIEEIRTTVGKNTVICGISGGVDSTVAAVL
VSKAIGKQLHCVFVDNGLLRKHEGDKVMKILKPLGLSVNLVDAEEIFLKRLKSIASPEKKRKIIGRTFIHIFEEQIHEEK
FLVQGTLYPDVIESVSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIDEDILMRHPFPGPGLAVR
VLGSVSKTRLDILRDADEIFLEELKSQNLYHHVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESSDGMTADWAHLPHE
FLSRVSNRIINEVRGINRVAYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-125 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-126 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-126 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-120 49