Gene Information

Name : Cphamn1_2065 (Cphamn1_2065)
Accession : YP_001960456.1
Strain : Chlorobium phaeobacteroides BS1
Genome accession: NC_010831
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2228506 - 2229252 bp
Length : 747 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGGAAATAGTGATCGTGATTCCTGCGAGGCTCGACTCAACCAGGTTACAGAGGAAAATGCTTGCAGACATAGAGGGTGA
ACCCCTCATTGTCAGAACCTGTCAGAATGCGATGAGGGCCGAATGCACTGACCGTGTTGTTGTAGCAACAGACAGTCCTG
AAATCGCGGAAGTACTCCGAAAAGTACATGTCGAGGTTGTCATGACCTCTCGACATGCGCGTTGCGGTTCGGAACGTATT
GCCGAAGCGGCGGAATCGCTTGAAGGCGATCTGTTTATCAATCTTCAGGGGGATGAGCCGTTGATCGATCCCGCTACTAT
TGACCTCGTGGCAGCACCATATCTTCGGGGAGAGAGGCCTGACTGTACAACGCTTGTTTTTCCTGTTCCGGCTGCAGAAA
CAGCCCTGATCGATGATCCGCATATCGTTAAAGCGGTCATTGATTCGAATGGATATGCGTTGTATTTTTCACGCAGTCCG
ATACCCTGTCGGAGGGGTGCGAACCTGTCGACCACCTTTTACCGTCATATCGGTATCTATGCGTTTCAGAGGGAAGTGCT
TCAGAAATTTGCCGGGCTCGAACCTTCAATGCTTGAAAAGGAAGAGTCTCTTGAACAGCTGCGACTTCTTGAAAACGGGT
TTCGTATTCAATGTGTTGAAACCACGGTTGACTCACCGGGAGTCAACACCCCCGAGGAACTGGAGTTTGTCAGAAGGATA
TTCAGGGAAGATCTTCCTTCCCTGTAA

Protein sequence :
MEIVIVIPARLDSTRLQRKMLADIEGEPLIVRTCQNAMRAECTDRVVVATDSPEIAEVLRKVHVEVVMTSRHARCGSERI
AEAAESLEGDLFINLQGDEPLIDPATIDLVAAPYLRGERPDCTTLVFPVPAAETALIDDPHIVKAVIDSNGYALYFSRSP
IPCRRGANLSTTFYRHIGIYAFQREVLQKFAGLEPSMLEKEESLEQLRLLENGFRIQCVETTVDSPGVNTPEELEFVRRI
FREDLPSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-37 41
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-38 41
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-37 41