Gene Information

Name : leuS (Aasi_1363)
Accession : YP_001958396.1
Strain : Candidatus Amoebophilus asiaticus 5a2
Genome accession: NC_010830
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 1737365 - 1740136 bp
Length : 2772 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGTCATTATGATTTTAAAGCCATTGAGCAGAAATGGCAACAATACTGGAAAAATAACCAAATCTTTCGTACAACCAT
AGAACCTAGCAAGCCCAAATACTATATTTTAGATATGTTCCCTTACCCTTCTGGTGAGGGACTCCATGTAGGCCACCCAC
TGGGCTATATTGCCTCGGATATTGTGGCTAGGTATAAAAGAAGCAAAGGATACCAGGTACTTCATCCAATGGGGTTTGAT
GCATTCGGTTTACCTGCAGAACAGTTTGCCATTCAAACAGGACAACATCCTGCTATAACTACTGCTAAAAATATAGGGCG
CTATAAGCAACAGCTTTGCCAGTTAGGACTTTCTTATGACTGGGACAGATGCATTAGCACATGCGAGCCAGCTTATTATA
AATGGACACAATGGATTTTTATACAATTGTTTAATAGTTGGTATGATATATCTCTACAAAAGGCTCGGCCTATTGATGAA
CTTATAACCTTATTTGACCAACAAGGCAATCAACAAGTACAAGCTAGCTGTGATAAAGAAGTGTCTTTATTTACTGCCAA
AGAATGGCAAGCAATGGATGAAGAGTCTAAACAACAGCATTTACTTGCCTATCGTTTAGCATTTTTAGAAGATACCACTG
TTAACTGGTGCCCTGAATTGGGAACCGTATTAGCCAATGAAGAAGTAAAAGATGGGCTTTCAGAACGAGGCGGATATCCT
GTTATACGTAAACAAATGAAGCAATGGAGTTTGCGTATTACTGCGTATACAGATAGACTACTAGCTGGTTTAGAACATCT
AAAATGGCCCTTGTCCACTAAAGAAATGCAACGTAACTGGATAGGTAGGTCGATAGGTGCTGAACTCAATTTTACAGTAA
TAGCTAATGGACAAGAGCATACGATCCCTGTATTTACTACGCGACCCGACACCTTATTTGGTGTTACCTATTTAGCACTG
TCTCCCGAACATCCATTAGCTAAGCTCATTAGTACAGGTACGCAACAAGCTGCTATAGATACTTATATTACTCAAGCTAC
TAACCGGTCTGAAAGAGATCGACTAGCGGATGTTAATCATGTTACTGGTATGTTTACAGGTGCTTATGCTATTCATCCTT
TTACTAAGCAGCCCTTACCTATTTGGATAGCAGACTACGTGTTAGCAGGCTATGGAACAGGAGCTGTAATGGGTGTACCT
GCACATGACAGCCGAGATTATGCTTTTGCACAACATTTTCAATTACCTATTATACAAGTAGTAGCAGGAGGAGACACTGC
TCAATCAGCTTATGAAGCAAGAGAAGGCAGCTTATTTAATTCTCAATTCTTGAATGGTCTTTCTATACAGGAAGCCACCA
AGCAAGCAATACAAAAGTTAGAGTCCTTAGGTATTGGAAAGCAAAAAACCACCTATCGACTACGTAATGCTATATTTAGC
AGGCAACGCTATTGGGGAGAACCTATTCCTATTTACTATAAAAATAATATACCATATCCTATTCCAGCAGAAGAGCTTCC
TTTAGAACTACCATCTTTAGCAAGCTTCAAGCCCACTCCTACTGGTGAGCCTCCACTAGGGCATGCTCCTAATTGGAAAA
CCAAAGAAGGTTATCCTATAGAGCTAAGCACCATGCCAGGATGGGCAGGATCTAGTTGGTATTTTTTTCGGTATATGGAT
CCTAATAATGAAGCAAGCTTTGTAGGCTCAACAGCACAGAATTACTGGCAAGCAGTAGACTTATATTTGGGTGGAGCAGA
ACACGCTACAGGCCATTTACTTTATGCGCGATTTTGGACTCAATTTTTATATGACTTGGGGTATGTGAACATAGAAGAAC
CGTTTCAAGAGCTTATTCACCAAGGGATGATACAAGGCAAGTCTAGCTTTGTGTATAGAATTAAAGGAACCAATCAGTTT
GTAAGCTATAACTTACGGCATGCATATGAAACCACTGCGATGCATGTTGATATTCATTTAGTAAAAAACAATATACTAGA
TCTCGAAAGATTTAAAAACTGGCGTCCTGATTTGCAGACCGCTACTTTTGTATTGGAAAACGGACAATATATATGTGGTA
GTGAGGTAGAAAAGATGTCTAAATCAAAATATAATACAGTAAATCCAGACACAGTAGTTGAGCAATACGGAGCAGACACT
TTAAGGTTATATACTATGTTCTTAGGACCTATTGAACAAGCCAAGCCTTGGGATATGCATGGTATAGAAGGTGTATTTAG
GTTCTTAGTTAAGGTATGGAGGCTATTTTACTTAGAAAAGGGGGCGATAATTACCAATGAAGTGCCTACTAAAGAAGTGC
AAAAGGCTATACATAAGGCTATTAAAAAAGTAGAAGAAGACATTAAGCGATATGCTTTTAATACAGCCGTAAGCAACTTA
ATGATCTGTGTTAATGAACTTACAGCCCTTAAGTGTAATAATCGGGCGGCACTAACCAACTTGGTACTTATATTAGCTCC
TTTTGCTCCGCATTTGGCTGAAGAACTTTGGGAAATACTAGGCCATCAGCATAGTATCGCACAAGCTCCTTTTCCAACAT
ATGAGGAAATATACTTGCAAGAAGAAACTTACGAATACCCAATTGCTATTAATGGCAAAGTACGTGCTAAAATTAATTTC
CCTGTTGACATGCCTCAAGGACAAATAGAAGAGCAAGTATTAACTCATGAAAGTATTCAAAAATGGATACAAGGACAACA
GATAAAAAGGGTTATTGTCATATCTTCCAAAATGGTTAATATTGTAATCTAA

Protein sequence :
MSHYDFKAIEQKWQQYWKNNQIFRTTIEPSKPKYYILDMFPYPSGEGLHVGHPLGYIASDIVARYKRSKGYQVLHPMGFD
AFGLPAEQFAIQTGQHPAITTAKNIGRYKQQLCQLGLSYDWDRCISTCEPAYYKWTQWIFIQLFNSWYDISLQKARPIDE
LITLFDQQGNQQVQASCDKEVSLFTAKEWQAMDEESKQQHLLAYRLAFLEDTTVNWCPELGTVLANEEVKDGLSERGGYP
VIRKQMKQWSLRITAYTDRLLAGLEHLKWPLSTKEMQRNWIGRSIGAELNFTVIANGQEHTIPVFTTRPDTLFGVTYLAL
SPEHPLAKLISTGTQQAAIDTYITQATNRSERDRLADVNHVTGMFTGAYAIHPFTKQPLPIWIADYVLAGYGTGAVMGVP
AHDSRDYAFAQHFQLPIIQVVAGGDTAQSAYEAREGSLFNSQFLNGLSIQEATKQAIQKLESLGIGKQKTTYRLRNAIFS
RQRYWGEPIPIYYKNNIPYPIPAEELPLELPSLASFKPTPTGEPPLGHAPNWKTKEGYPIELSTMPGWAGSSWYFFRYMD
PNNEASFVGSTAQNYWQAVDLYLGGAEHATGHLLYARFWTQFLYDLGYVNIEEPFQELIHQGMIQGKSSFVYRIKGTNQF
VSYNLRHAYETTAMHVDIHLVKNNILDLERFKNWRPDLQTATFVLENGQYICGSEVEKMSKSKYNTVNPDTVVEQYGADT
LRLYTMFLGPIEQAKPWDMHGIEGVFRFLVKVWRLFYLEKGAIITNEVPTKEVQKAIHKAIKKVEEDIKRYAFNTAVSNL
MICVNELTALKCNNRAALTNLVLILAPFAPHLAEELWEILGHQHSIAQAPFPTYEEIYLQEETYEYPIAINGKVRAKINF
PVDMPQGQIEEQVLTHESIQKWIQGQQIKRVIVISSKMVNIVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-133 44