Gene Information

Name : hemC (Glov_0502)
Accession : YP_001950750.1
Strain : Geobacter lovleyi SZ
Genome accession: NC_010814
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 477622 - 478560 bp
Length : 939 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGGCACCTAAACGCCTCCGCATAGGCACCCGCGCCAGCCAGCTGGCCCTCTGGCAGGCCAACTGGACCAAATCGGAACT
GGAAGCAAGGTATCCCGGCATCCAGGTTGAACTGGTCAAGATCAAGACCATGGGAGACAAGATCCTGGATGTCCCACTGG
CACAGGTTGGTGGCAAAGGACTGTTTGTCAAAGAGATCGAAGAGGCAATGCTGCGGGGTGAGATCGACCTGGCCGTACAC
AGCATGAAGGATGTCCCGACTGAGTTCCCTGAAGGACTGGGACTGGTGGTAACCACCAAGCGTGAAGACCCCCGTGACGC
CTTTATCTCGGACAAGGTAACATTCAGCGAACTGCGCCAGGGAGCCAGAATAGGCACCAGTGCCCTGCGCAGACAGGCCC
AGCTGCTCAAGGCGCGGCCCGACCTGGAGATGGTGATTATCCGCGGCAACGTTGAGACCCGTATTCGCAAGCTGAAGGAA
GACAATCTGGATGCCGTGATCCTGGCAGCGGCCGGCCTGAACCGGCTCGGCTTCACCGACGTGGTGACCGAGCTGCTGGA
TACGGACTTCTCGATCCCGGCCATCGGCCAGGGCGCCCTGGGACTGGAGTGCCGCCTGGATGACAACGCCACCATCGAGG
CGCTGGCCTTCCTGAATCATGCCGATACCGCTGCTGCAGTGGCCGCAGAACGGGCGCTGCTCAAACGCTGTGAAGGTGGT
TGCCAGGTACCGATTGCCGCCCACGGCACGGTGAGCGGTGACACCCTGACCCTGGTCGGTTTTATCGCCTCGGTGGATGG
CAAACAGACGGTACGGGACCGCATCAGCGGATCAACAGCGGATGCGGTAAAACTGGGAACAGAACTGGCCGACCGGTTGC
TGGCAGCTGGAGGCAAGGCGATTCTGGAAGATGTCTACCAGCGGGAAATTGCCCACTAG

Protein sequence : 
MAPKRLRIGTRASQLALWQANWTKSELEARYPGIQVELVKIKTMGDKILDVPLAQVGGKGLFVKEIEEAMLRGEIDLAVH
SMKDVPTEFPEGLGLVVTTKREDPRDAFISDKVTFSELRQGARIGTSALRRQAQLLKARPDLEMVIIRGNVETRIRKLKE
DNLDAVILAAAGLNRLGFTDVVTELLDTDFSIPAIGQGALGLECRLDDNATIEALAFLNHADTAAAVAAERALLKRCEGG
CQVPIAAHGTVSGDTLTLVGFIASVDGKQTVRDRISGSTADAVKLGTELADRLLAAGGKAILEDVYQREIAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-64 51
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-64 51